6C0V

Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation

Summary for 6C0V

• Entry DOI: 10.2210/pdb6c0v/pdb
• EMDB information: 7325
• Descriptor: Multidrug resistance protein 1, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION (3 entities in total)
• Functional Keywords: abc transporter; abcb1; p-glycoprotein; cryo-em; multidrug resistance, structural genomics, psi-2, protein structure initiative, transport protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 143723.89

Authors

Kim, Y.J.,Chen, J. (deposition date: 2018-01-02, release date: 2018-01-31, Last modification date: 2024-03-13)

• Primary citation: Kim, Y.,Chen, J.; Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation.; Science, 359:915-919, 2018; PubMed: 29371429; DOI: 10.1126/science.aar7389

Experimental method

ELECTRON MICROSCOPY (3.4 Å)