6B89

E. coli LptB in complex with ADP and novobiocin

Summary for 6B89

• Entry DOI: 10.2210/pdb6b89/pdb
• Descriptor: Lipopolysaccharide export system ATP-binding protein LptB, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: lptb, abc transporter, lps transport, lipid transport, activator, lipid transport-activator complex, lipid transport/activator
• Biological source: Escherichia coli (strain K12)
• Total number of polymer chains: 2
• Total formula weight: 58009.78

Authors

May, J.M.,Lazarus, M.B.,Sherman, D.J.,Owens, T.W.,Mandler, M.D.,Kahne, D.K. (deposition date: 2017-10-05, release date: 2017-12-06, Last modification date: 2023-10-04)

• Primary citation: May, J.M.,Owens, T.W.,Mandler, M.D.,Simpson, B.W.,Lazarus, M.B.,Sherman, D.J.,Davis, R.M.,Okuda, S.,Massefski, W.,Ruiz, N.,Kahne, D.; The Antibiotic Novobiocin Binds and Activates the ATPase That Powers Lipopolysaccharide Transport.; J. Am. Chem. Soc., 139:17221-17224, 2017; PubMed: 29135241; DOI: 10.1021/jacs.7b07736

Experimental method

X-RAY DIFFRACTION (2 Å)