6BHU
Cryo-EM structure of ATP-bound, outward-facing bovine multidrug resistance protein 1 (MRP1)
Summary for 6BHU
Entry DOI | 10.2210/pdb6bhu/pdb |
Related | 5UJ9 5UJA |
EMDB information | 7099 |
Descriptor | Multidrug resistance-associated protein 1, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | abc transporter, multidrug resistance, outward facing, transport protein |
Biological source | Bos taurus (Bovine) |
Total number of polymer chains | 1 |
Total formula weight | 185297.00 |
Authors | Johnson, Z.L.,Chen, J. (deposition date: 2017-10-31, release date: 2017-12-27, Last modification date: 2024-03-13) |
Primary citation | Johnson, Z.L.,Chen, J. ATP Binding Enables Substrate Release from Multidrug Resistance Protein 1. Cell, 172:81-89.e10, 2018 Cited by PubMed: 29290467DOI: 10.1016/j.cell.2017.12.005 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.14 Å) |
Structure validation
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