5UJA
Cryo-EM structure of bovine multidrug resistance protein 1 (MRP1) bound to leukotriene C4
Summary for 5UJA
Entry DOI | 10.2210/pdb5uja/pdb |
Related | 5UJ9 |
EMDB information | 8559 8560 |
Descriptor | bovine multidrug resistance protein 1 (MRP1),Multidrug resistance-associated protein 1, (5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-[[(4~{S})-4-azanyl-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]-3-( 2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid (2 entities in total) |
Functional Keywords | abc transporter, multidrug resistance, leukotriene c4, ltc4, protein transport |
Biological source | Bos taurus More |
Total number of polymer chains | 1 |
Total formula weight | 160327.70 |
Authors | Johnson, Z.L.,Chen, J. (deposition date: 2017-01-17, release date: 2017-02-22, Last modification date: 2024-03-13) |
Primary citation | Johnson, Z.L.,Chen, J. Structural Basis of Substrate Recognition by the Multidrug Resistance Protein MRP1. Cell, 168:1075-1085.e9, 2017 Cited by PubMed: 28238471DOI: 10.1016/j.cell.2017.01.041 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.34 Å) |
Structure validation
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