5UJA

Cryo-EM structure of bovine multidrug resistance protein 1 (MRP1) bound to leukotriene C4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	bovine multidrug resistance protein 1 (MRP1),Multidrug resistance-associated protein 1	polymer	1460	159701.9	1	UniProt (Q8HXQ5) Pfam (PF00664) Pfam (PF00005)	Bos taurus	ATP-binding cassette sub-family C member 1,Leukotriene C(4) transporter,LTC4 transporter
2	B (A)	(5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-[[(4~{S})-4-azanyl-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]-3-( 2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid	non-polymer		625.8	1	Chemie (LTX)

Sequence modifications

A: 31 - 194 (PDB: 5UJA)
A: 205 - 1530 (UniProt: Q8HXQ5)

PDB	External Database	Details
Ser 1531	-	expression tag
Asn 1532	-	expression tag
Ser 1533	-	expression tag
Leu 1534	-	expression tag
Glu 1535	-	expression tag
Val 1536	-	expression tag
Leu 1537	-	expression tag
Phe 1538	-	expression tag
Gln 1539	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	159701.9
Non-Polymers*	Number of molecules	1
	Total formula weight	625.8
All*	Total formula weight	160327.7

*Water molecules are not included.