6UK1
 
 | | Crystal structure of nucleotide-binding domain 2 (NBD2) of the human Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | | 著者 | Wang, C, Vorobiev, S.M, Vernon, R.M, Khazanov, N, Senderowitz, H, Forman-Kay, J.D, Hunt, J.F. | | 登録日 | 2019-10-03 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.693 Å) | | 主引用文献 | A thermodynamically stabilized form of the second nucleotide binding domain from human CFTR shows a catalytically inactive conformation
To Be Published
|
|
6UJN
 | | P-glycoprotein mutant-C952A-with BDE100 | | 分子名称: | 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1 | | 著者 | Aller, S.G, Le, C.A. | | 登録日 | 2019-10-03 | | 公開日 | 2020-05-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.98 Å) | | 主引用文献 | Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
|
|
6UY0
 | |
6TEJ
 | | Structure of apo IrtAB devoid SID in complex with sybody Syb_NL5 | | 分子名称: | DECYL-BETA-D-MALTOPYRANOSIDE, Drug ABC transporter ATP-binding protein, NICKEL (II) ION, ... | | 著者 | Gonda, I, Arnold, F.M, Hutter, C.A.J, Weber, M.S, Seeger, M.A, Hurlimann, L.M. | | 登録日 | 2019-11-12 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The ABC exporter IrtAB imports and reduces mycobacterial siderophores.
Nature, 580, 2020
|
|
6UZ2
 | | Cryo-EM structure of nucleotide-free MsbA reconstituted into peptidiscs, conformation 1 | | 分子名称: | Lipid A export ATP-binding/permease protein MsbA | | 著者 | Angiulli, G, Walz, T, Dhupar, H.S, Suzuki, H, Wason, I.S, Duong Van Hoa, F. | | 登録日 | 2019-11-14 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | New approach for membrane protein reconstitution into peptidiscs and basis for their adaptability to different proteins.
Elife, 9, 2020
|
|
6UZL
 | | Cryo-EM structure of nucleotide-free MsbA reconstituted into peptidiscs, conformation 2 | | 分子名称: | Lipid A export ATP-binding/permease protein MsbA | | 著者 | Angiulli, G, Walz, T, Dhupar, H.S, Suzuki, H, Wason, I.S, Duong Van Hoa, F. | | 登録日 | 2019-11-15 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | New approach for membrane protein reconstitution into peptidiscs and basis for their adaptability to different proteins.
Elife, 9, 2020
|
|
6TMF
 | | Structure of an archaeal ABCE1-bound ribosomal post-splitting complex | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Kratzat, H, Becker, T, Tampe, R, Beckmann, R. | | 登録日 | 2019-12-04 | | 公開日 | 2020-02-12 | | 最終更新日 | 2020-05-13 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex.
Embo J., 39, 2020
|
|
6TQF
 | | The structure of ABC transporter Rv1819c in AMP-PNP bound state | | 分子名称: | ABC transporter ATP-binding protein/permease, DODECYL-BETA-D-MALTOSIDE, MAGNESIUM ION, ... | | 著者 | Rempel, S, Gati, C, Slotboom, D.J, Guskov, A. | | 登録日 | 2019-12-16 | | 公開日 | 2020-04-01 | | 最終更新日 | 2021-02-10 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds.
Nature, 580, 2020
|
|
6TQE
 | | The structure of ABC transporter Rv1819c without addition of substrate | | 分子名称: | ABC transporter ATP-binding protein/permease, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | | 著者 | Rempel, S, Gati, C, Slotboom, D.J, Guskov, A. | | 登録日 | 2019-12-16 | | 公開日 | 2020-04-01 | | 最終更新日 | 2021-02-10 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds.
Nature, 580, 2020
|
|
6V9Z
 | |
6LR0
 | | structure of human bile salt exporter ABCB11 | | 分子名称: | Bile salt export pump | | 著者 | Wang, L, Hou, W.T, Chen, L, Jiang, Y.L, Xu, D, Sun, L.F, Zhou, C.Z, Chen, Y. | | 登録日 | 2020-01-15 | | 公開日 | 2020-04-15 | | 最終更新日 | 2023-01-18 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structure of human bile salts exporter ABCB11.
Cell Res., 30, 2020
|
|
6VQU
 | |
6VQT
 | |
6VXF
 | | Structure of apo-closed ABCG2 | | 分子名称: | Broad substrate specificity ATP-binding cassette transporter ABCG2 | | 著者 | Orlando, B.J, Maofu, L. | | 登録日 | 2020-02-21 | | 公開日 | 2020-05-13 | | 最終更新日 | 2020-05-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | ABCG2 transports anticancer drugs via a closed-to-open switch.
Nat Commun, 11, 2020
|
|
6VXH
 | | Structure of ABCG2 bound to imatinib | | 分子名称: | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL | | 著者 | Orlando, B.J, Liao, M. | | 登録日 | 2020-02-21 | | 公開日 | 2020-05-13 | | 最終更新日 | 2020-05-20 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | ABCG2 transports anticancer drugs via a closed-to-open switch.
Nat Commun, 11, 2020
|
|
6VXI
 | | Structure of ABCG2 bound to mitoxantrone | | 分子名称: | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL | | 著者 | Orlando, B.J, Liao, M. | | 登録日 | 2020-02-21 | | 公開日 | 2020-05-13 | | 最終更新日 | 2020-05-20 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | ABCG2 transports anticancer drugs via a closed-to-open switch.
Nat Commun, 11, 2020
|
|
6VXJ
 | | Structure of ABCG2 bound to SN38 | | 分子名称: | 7-ethyl-10-hydroxycamptothecin, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL | | 著者 | Orlando, B.J, Liao, M. | | 登録日 | 2020-02-22 | | 公開日 | 2020-05-13 | | 最終更新日 | 2020-05-20 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | ABCG2 transports anticancer drugs via a closed-to-open switch.
Nat Commun, 11, 2020
|
|
6YAL
 | | Mammalian 48S late-stage initiation complex with beta-globin mRNA | | 分子名称: | 18S ribosomal RNA, 40S Ribosomal protein uS3, 40S Ribosomal protein uS7, ... | | 著者 | Bochler, A, Simonetti, A, Guca, E, Hashem, Y. | | 登録日 | 2020-03-12 | | 公開日 | 2020-04-08 | | 最終更新日 | 2020-04-22 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
|
|
6WBS
 | | Human CFTR first nucleotide binding domain with dF508/V510D | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | | 著者 | Simon, K.S, Kothe, M, Hilbert, B, Batchelor, J.D, Hurlbut, G.D. | | 登録日 | 2020-03-27 | | 公開日 | 2021-04-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.857 Å) | | 主引用文献 | Determining the Molecular Mechanism of Suppressor Mutation V510D and the Contribution of Helical Unraveling to the dF508-CFTR Defect
To Be Published
|
|
6YIR
 | |
6Z4W
 | | FtsE structure from Streptococcus pneumoniae in complex with ADP (space group P 1) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE | | 著者 | Alcorlo, M, Straume, D, Hermoso, J.A, Havarstein, L.S. | | 登録日 | 2020-05-26 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Structural Characterization of the Essential Cell Division Protein FtsE and Its Interaction with FtsX in Streptococcus pneumoniae.
Mbio, 11, 2020
|
|
6Z5U
 | |
6Z63
 | | FtsE structure from Streptococus pneumoniae in complex with ADP at 1.57 A resolution (spacegroup P 21) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE | | 著者 | Alcorlo, M, Straume, D, Havarstein, L.S, Hermoso, J.A. | | 登録日 | 2020-05-27 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Structural Characterization of the Essential Cell Division Protein FtsE and Its Interaction with FtsX in Streptococcus pneumoniae.
Mbio, 11, 2020
|
|
6Z67
 | | FtsE structure of Streptococcus pneumoniae in complex with AMPPNP at 2.4 A resolution | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Alcorlo, M, Straume, D, Havarstein, L.S, Hermoso, j.A. | | 登録日 | 2020-05-28 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Characterization of the Essential Cell Division Protein FtsE and Its Interaction with FtsX in Streptococcus pneumoniae.
Mbio, 11, 2020
|
|
7CAF
 | | Mycobacterium smegmatis LpqY-SugABC complex in the pre-translocation state | | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | | 著者 | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | | 登録日 | 2020-06-08 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.
Sci Adv, 6, 2020
|
|
