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6VXF

Structure of apo-closed ABCG2

Summary for 6VXF
Entry DOI10.2210/pdb6vxf/pdb
EMDB information21436 21437 21438 21439 21440 21441
DescriptorBroad substrate specificity ATP-binding cassette transporter ABCG2 (1 entity in total)
Functional Keywordsabcg2, bcrp, nanodisc, abc transporter, translocase
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight144771.70
Authors
Orlando, B.J.,Maofu, L. (deposition date: 2020-02-21, release date: 2020-05-13, Last modification date: 2020-05-20)
Primary citationOrlando, B.J.,Liao, M.
ABCG2 transports anticancer drugs via a closed-to-open switch.
Nat Commun, 11:2264-2264, 2020
Cited by
PubMed: 32385283
DOI: 10.1038/s41467-020-16155-2
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.5 Å)
Structure validation

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