PDB: 316 件ウェブページステータス検索Chemie searchBIRD

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4RYF	ClpP1/2 heterocomplex from Listeria monocytogenes 分子名称: ATP-dependent Clp protease proteolytic subunit, MALONATE ION, SODIUM ION 著者 Dahmen, M, Vielberg, M.-T, Groll, M, Sieber, S.A. 登録日 2014-12-15 公開日 2014-12-31 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure and mechanism of the caseinolytic protease ClpP1/2 heterocomplex from Listeria monocytogenes. Angew.Chem.Int.Ed.Engl., 54, 2015
3PMI	PWWP Domain of Human Mutated Melanoma-Associated Antigen 1 分子名称: DI(HYDROXYETHYL)ETHER, PWWP domain-containing protein MUM1, SULFATE ION, ... 著者 Lam, R, Zeng, H, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC) 登録日 2010-11-17 公開日 2010-12-15 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Structural and histone binding ability characterizations of human PWWP domains. Plos One, 6, 2011
3VU3	Crystal structure of the Hfq and catalase HPII complex 分子名称: Catalase HPII, PROTOPORPHYRIN IX CONTAINING FE, Protein hfq 著者 Watanabe, M, Yonekura, K. 登録日 2012-06-15 公開日 2013-11-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Post-Transcriptional Regulator Hfq Binds Catalase HPII: Crystal Structure of the Complex Plos One, 8, 2013
4BIW	Crystal structure of CpxAHDC (hexagonal form) 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SENSOR PROTEIN CPXA, ... 著者 Mechaly, A.E, Sassoon, N, Betton, J.M, Alzari, P.M. 登録日 2013-04-13 公開日 2014-02-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation. Plos Biol., 12, 2014
4BUR	Crystal structure of the reduced human Apoptosis inducing factor complexed with NAD 分子名称: APOPTOSIS INDUCING FACTOR 1, MITOCHONDRIAL, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Martinez-Julvez, M, Herguedas, B, Hermoso, J.A, Ferreira, P, Villanueva, R, Medina, M. 登録日 2013-06-23 公開日 2014-07-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 Structural Insights Into the Coenzyme Mediated Monomer-Dimer Transition of the Pro-Apoptotic Apoptosis Inducing Factor. Biochemistry, 53, 2014
6CK3	Co-crytsal Structure of MNK2 in Complex With an Inhibitor 分子名称: (3R)-3-methyl-5-[(pyrimidin-4-yl)amino]-2,3-dihydro-1H-isoindol-1-one, CHLORIDE ION, MAP kinase-interacting serine/threonine-protein kinase 2, ... 著者 Han, Q. 登録日 2018-02-27 公開日 2018-05-09 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018
7AHN	Cryo-EM structure of F-actin stabilized by cis-optoJASP-8 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Pospich, S, Raunser, S. 登録日 2020-09-24 公開日 2021-01-27 最終更新日 2021-04-14 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Cryo-EM Resolves Molecular Recognition Of An Optojasp Photoswitch Bound To Actin Filaments In Both Switch States. Angew.Chem.Int.Ed.Engl., 60, 2021
5IUK	Crystal structure of the DesK-DesR complex in the phosphotransfer state with high Mg2+ (150 mM) 分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... 著者 Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A. 登録日 2016-03-18 公開日 2016-12-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action. Elife, 5, 2016
4FWJ	Native structure of LSD2/AOF1/KDM1b in spacegroup of I222 at 2.9A 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, PHOSPHATE ION, ... 著者 Zhang, Q, Chen, Z. 登録日 2012-07-01 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b Cell Res., 23, 2013
4GA7	Crystal structure of human serpinB1 mutant 分子名称: Leukocyte elastase inhibitor 著者 Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z. 登録日 2012-07-25 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Identification of SERPINB1 as a physiological inhibitor of human granzyme H J.Immunol., 190, 2013
4G3D	Crystal structure of human NF-kappaB inducing kinase (NIK) 分子名称: MAGNESIUM ION, NF-kappa-beta-inducing kinase 著者 Hymowitz, S.G, de Leon-Boenig, G. 登録日 2012-07-13 公開日 2012-08-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site. Structure, 20, 2012
4MFJ	The crystal structure of acyltransferase 分子名称: Putative uncharacterized protein tcp24 著者 Lyu, S.Y, Liu, Y.C, Chang, C.Y, Huang, C.J, Li, T.L. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc., 136, 2014
4BH6	Insights into degron recognition by APC coactivators from the structure of an Acm1-Cdh1 complex 分子名称: APC/C ACTIVATOR PROTEIN CDH1, APC/C-CDH1 MODULATOR 1 著者 He, J, Chao, W.C.H, Zhang, Z, Yang, J, Cronin, N, Barford, D. 登録日 2013-03-29 公開日 2013-06-05 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Insights Into Degron Recognition by Apc/C Coactivators from the Structure of an Acm1-Cdh1 Complex. Mol.Cell, 50, 2013
4GW9	Structure of a bacteriophytochrome and light-stimulated protomer swapping with a gene repressor 分子名称: BILIVERDINE IX ALPHA, bacteriophytochrome 著者 Bellini, D, Papiz, M.Z. 登録日 2012-09-01 公開日 2012-09-26 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of a bacteriophytochrome and light-stimulated protomer swapping with a gene repressor. Structure, 20, 2012
6CKI	Co-crystal structure of MNK2 in Complex With Inhibitor 分子名称: 3,3-dimethyl-6-[(pyrimidin-4-yl)amino]-2,3-dihydroimidazo[1,5-a]pyridine-1,5-dione, MAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION 著者 Han, Q. 登録日 2018-02-28 公開日 2018-05-09 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018
4UIP	The complex structure of extracellular domain of EGFR with Repebody (rAC1). 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EPIDERMAL GROWTH FACTOR RECEPTOR, ... 著者 Kang, Y.J, Cha, Y.J, Cho, H.S, Lee, J.J, Kim, H.S. 登録日 2015-03-31 公開日 2015-11-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Enzymatic Prenylation and Oxime Ligation for the Synthesis of Stable and Homogeneous Protein-Drug Conjugates for Targeted Therapy. Angew.Chem.Int.Ed.Engl., 54, 2015
5HK7	Bacterial sodium channel pore, 2.95 Angstrom resolution 分子名称: 2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}ethyl heptadecanoate, CHLORIDE ION, Ion transport protein, ... 著者 Shaya, D, Findeisen, F, Rohaim, A, Minor, D.L. 登録日 2016-01-14 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation. Cell, 164, 2016
7EMN	The atomic structure of SHP2 E76A mutant 分子名称: Tyrosine-protein phosphatase non-receptor type 11 著者 Luo, F, Xie, J.J, Zhu, J.D, Liu, C. 登録日 2021-04-14 公開日 2021-05-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A novel partially open state of SHP2 points to a "multiple gear" regulation mechanism. J.Biol.Chem., 296, 2021
4J2Q	Crystal structure of C-terminally truncated arrestin reveals mechanism of arrestin activation 分子名称: S-arrestin 著者 Kim, Y.J, Scheerer, P, Choe, H.-W. 登録日 2013-02-05 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of pre-activated arrestin p44. Nature, 497, 2013
4DGL	Crystal Structure of the CK2 Tetrameric Holoenzyme 分子名称: Casein kinase II subunit alpha, Casein kinase II subunit beta, ZINC ION 著者 Lolli, G, Battistutta, R. 登録日 2012-01-26 公開日 2012-05-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural determinants of protein kinase CK2 regulation by autoinhibitory polymerization. Acs Chem.Biol., 7, 2012
6RMQ	Crystal structure of a selenomethionine-substituted A70M I84M mutant of the essential repressor DdrO from radiation resistant-Deinococcus bacteria (Deinococcus deserti) 分子名称: HTH-type transcriptional regulator DdrOC 著者 Arnoux, P, Siponen, M.I, Pignol, D, De Groot, A, Blanchard, L. 登録日 2019-05-07 公開日 2019-10-09 最終更新日 2019-12-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of the transcriptional repressor DdrO: insight into the metalloprotease/repressor-controlled radiation response in Deinococcus. Nucleic Acids Res., 47, 2019
4K2R	Structural basis for activation of ZAP-70 by phosphorylation of the SH2-kinase linker 分子名称: MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Yan, Q, Barros, T, Visperas, P.R, Deindl, S, Kadlecek, T.A, Weiss, A, Kuriyan, J. 登録日 2013-04-09 公開日 2013-05-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Basis for Activation of ZAP-70 by Phosphorylation of the SH2-Kinase Linker. Mol.Cell.Biol., 33, 2013
5C7J	CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT 分子名称: E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C 著者 Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) 登録日 2015-06-24 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016
4GAW	Crystal structure of active human granzyme H 分子名称: CHLORIDE ION, Granzyme H, SULFATE ION 著者 Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z. 登録日 2012-07-25 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Identification of SERPINB1 as a physiological inhibitor of human granzyme H J.Immunol., 190, 2013
4GRS	Crystal structure of a chimeric DAH7PS 分子名称: Phospho-2-dehydro-3-deoxyheptonate aldolase, 2-dehydro-3-deoxyphosphoheptonate aldolase, TYROSINE 著者 Cross, P.J, Allison, T.M, Dobson, R.C.J, Jameson, G.B, Parker, E.J. 登録日 2012-08-26 公開日 2013-02-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain Proc.Natl.Acad.Sci.USA, 110, 2013

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