4BUR

Crystal structure of the reduced human Apoptosis inducing factor complexed with NAD

Summary for 4BUR

Entry DOI	10.2210/pdb4bur/pdb
Related	4BV6
Descriptor	APOPTOSIS INDUCING FACTOR 1, MITOCHONDRIAL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total)
Functional Keywords	apoptosis, mitochondria, nuclear chromatinolysis, dna-binding, flavoprotein, oxidoreductase
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Mitochondrion intermembrane space. Isoform 3: Mitochondrion intermembrane space. Isoform 5: Cytoplasm: O95831
Total number of polymer chains	4
Total formula weight	231634.83
Authors	Martinez-Julvez, M.,Herguedas, B.,Hermoso, J.A.,Ferreira, P.,Villanueva, R.,Medina, M. (deposition date: 2013-06-23, release date: 2014-07-09, Last modification date: 2023-12-20)
Primary citation	Ferreira, P.,Villanueva, R.,Martinez-Julvez, M.,Herguedas, B.,Marcuello, C.,Fernandez-Silva, P.,Cabon, L.,Hermoso, J.A.,Lostao, A.,Susin, S.A.,Medina, M. Structural Insights Into the Coenzyme Mediated Monomer-Dimer Transition of the Pro-Apoptotic Apoptosis Inducing Factor. Biochemistry, 53:4204-, 2014 Cited by PubMed: 24914854 DOI: 10.1021/BI500343R PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.88 Å)

Structure validation