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5W6Q
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BU of 5w6q by Molmil
Structural basis for recognition of artificial DNA by an evolved KlenTaq variant
Descriptor: DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(1W5))-3'), DNA (5'-D(P*GP*(1WA)P*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA polymerase I, ...
Authors:Singh, I, Georgiadis, M.M.
Deposit date:2017-06-16
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide.
Nucleic Acids Res., 46, 2018
4Z49
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BU of 4z49 by Molmil
Homo Sapiens Fatty Acid Synthetase, Thioesterase Domain at 1.7 Angstroms Resolution
Descriptor: Fatty acid synthase, POTASSIUM ION
Authors:Spraggon, G.
Deposit date:2015-04-01
Release date:2016-03-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Estimation of Hydrogen-Exchange Protection Factors from MD Simulation Based on Amide Hydrogen Bonding Analysis.
J.Chem.Inf.Model., 55, 2015
4ZPV
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BU of 4zpv by Molmil
Structure of MERS-Coronavirus Spike Receptor-binding Domain (England1 Strain) in Complex with Vaccine-Elicited Murine Neutralizing Antibody D12 (Crystal Form 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, D12 Fab Heavy chain, D12 Fab light chain, ...
Authors:Joyce, M.G, Mascola, J.R, Graham, B.S, Kwong, P.D.
Deposit date:2015-05-08
Release date:2015-10-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Evaluation of candidate vaccine approaches for MERS-CoV.
Nat Commun, 6, 2015
5VV2
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BU of 5vv2 by Molmil
Structure of human neuronal nitric oxide synthase heme domain in complex with 7-(((3-(5-Fluoropyridin-3-yl)propyl)amino)methyl)quinolin-2-amine
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-({[3-(5-fluoropyridin-3-yl)propyl]amino}methyl)quinolin-2-amine, Nitric oxide synthase, ...
Authors:Huiying, L, Thomas, L.P.
Deposit date:2017-05-19
Release date:2017-08-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors.
J. Med. Chem., 60, 2017
6CRR
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BU of 6crr by Molmil
CryoEM structure of human enterovirus D68 full native virion (pH 7.2 and 4 degrees Celsius)
Descriptor: viral protein 1, viral protein 2, viral protein 3, ...
Authors:Liu, Y, Rossmann, M.G.
Deposit date:2018-03-19
Release date:2018-12-19
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2NTU
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BU of 2ntu by Molmil
Bacteriorhodopsin, wild type, before illumination
Descriptor: Bacteriorhodopsin, RETINAL
Authors:Lanyi, J.K, Schobert, B.
Deposit date:2006-11-08
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Structural changes in the L photointermediate of bacteriorhodopsin.
J.Mol.Biol., 365, 2007
6CWT
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BU of 6cwt by Molmil
Hepatitis B core-antigen in complex with Fab e21
Descriptor: Capsid protein, Fab e21 heavy chain, Fab e21 light chain
Authors:Eren, E, Steven, A.C, Wingfield, P.T.
Deposit date:2018-03-30
Release date:2018-08-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.151 Å)
Cite:Structures of Hepatitis B Virus Core- and e-Antigen Immune Complexes Suggest Multi-point Inhibition.
Structure, 26, 2018
6CXH
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BU of 6cxh by Molmil
Crystal structure of particulate methane monooxygenase from Methylomicrobium alcaliphilum 20Z
Descriptor: 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, COPPER (II) ION, Particulate methane monooxygenase, ...
Authors:Ro, S.Y, Rosenzweig, A.C.
Deposit date:2018-04-03
Release date:2018-05-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:From micelles to bicelles: Effect of the membrane on particulate methane monooxygenase activity.
J. Biol. Chem., 293, 2018
4Z6R
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BU of 4z6r by Molmil
Structure of H200E variant of Homoprotocatechuate 2,3-Dioxygenase from B.fuscum in complex with 4-sulfonyl catechol at 1.70 Ang resolution
Descriptor: 1,2-ETHANEDIOL, 3,4-dihydroxybenzenesulfonic acid, CALCIUM ION, ...
Authors:Kovaleva, E.G, Lipscomb, J.D.
Deposit date:2015-04-06
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200.
Biochemistry, 54, 2015
6CYR
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BU of 6cyr by Molmil
Crystal structure of the UBE2A variant Q93E
Descriptor: Ubiquitin-conjugating enzyme E2 A
Authors:Ranzani, A.T, de Oliveira, J.F.
Deposit date:2018-04-06
Release date:2018-12-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanistic insights revealed by a UBE2A mutation linked to intellectual disability.
Nat. Chem. Biol., 15, 2019
6CYY
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BU of 6cyy by Molmil
Mycobacterium tuberculosis transcriptional regulator
Descriptor: COENZYME A, HTH-type transcriptional regulator PrpR, IRON/SULFUR CLUSTER
Authors:Tang, S, Sacchettini, J.
Deposit date:2018-04-07
Release date:2019-04-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:Structural and functional insight into the Mycobacterium tuberculosis protein PrpR reveals a novel type of transcription factor.
Nucleic Acids Res., 47, 2019
4Z88
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BU of 4z88 by Molmil
SH3-II of Drosophila Rim-binding protein with Aplip1 peptide
Descriptor: JNK-interacting protein 1, PHOSPHATE ION, RIM-binding protein, ...
Authors:Driller, J.H, Holton, N, Siebert, M, Boehme, M.A, Wahl, M.C, Sigrist, S.J, Loll, B.
Deposit date:2015-04-08
Release date:2015-08-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:A high affinity RIM-binding protein/Aplip1 interaction prevents the formation of ectopic axonal active zones.
Elife, 4, 2015
2OJG
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BU of 2ojg by Molmil
Crystal structure of ERK2 in complex with N,N-dimethyl-4-(4-phenyl-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide
Descriptor: Mitogen-activated protein kinase 1, N,N-DIMETHYL-4-(4-PHENYL-1H-PYRAZOL-3-YL)-1H-PYRROLE-2-CARBOXAMIDE, SULFATE ION
Authors:Xie, X, Jacobs, M.D.
Deposit date:2007-01-12
Release date:2007-02-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Flipped Out: Structure-Guided Design of Selective Pyrazolylpyrrole ERK Inhibitors.
J.Med.Chem., 50, 2007
4Z98
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BU of 4z98 by Molmil
Crystal Structure of Hen Egg White Lysozyme using Serial X-ray Diffraction Data Collection
Descriptor: ACETATE ION, Lysozyme C
Authors:Murray, T.D, Lyubimov, A.Y, Ogata, C.M, Uervirojnangkoorn, M, Brunger, A.T, Berger, J.M.
Deposit date:2015-04-10
Release date:2015-10-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A high-transparency, micro-patternable chip for X-ray diffraction analysis of microcrystals under native growth conditions.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
6CYA
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BU of 6cya by Molmil
Rotavirus SA11 NSP2 S313A mutant
Descriptor: CHLORIDE ION, GLYCEROL, Non-structural protein 2
Authors:Anish, R, Hu, L, Prasad, B.V.V.
Deposit date:2018-04-05
Release date:2018-12-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Phosphorylation cascade regulates the formation and maturation of rotaviral replication factories.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6D1P
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BU of 6d1p by Molmil
Apo structure of Bacteroides uniformis beta-glucuronidase 3
Descriptor: GLYCEROL, Glycosyl hydrolases family 2, sugar binding domain protein, ...
Authors:Walton, W.G, Pellock, S.J, Redinbo, M.R.
Deposit date:2018-04-12
Release date:2018-10-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
2NTW
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BU of 2ntw by Molmil
Bacteriorhodopsin, wild type, after illumination to produce the L intermediate
Descriptor: Bacteriorhodopsin, RETINAL
Authors:Lanyi, J.K, Schobert, B.
Deposit date:2006-11-08
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Structural changes in the L photointermediate of bacteriorhodopsin.
J.Mol.Biol., 365, 2007
2NYE
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BU of 2nye by Molmil
Crystal structure of the Bateman2 domain of yeast Snf4
Descriptor: Nuclear protein SNF4
Authors:Rudolph, M.J, Amodeo, G.A, Iram, S, Hong, S, Pirino, G, Carlson, M, Tong, L.
Deposit date:2006-11-20
Release date:2006-12-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Bateman2 domain of yeast Snf4: dimeric association and relevance for AMP binding.
Structure, 15, 2007
6CHP
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BU of 6chp by Molmil
Phosphopantetheine adenylyltransferase (CoaD) in complex with methyl (R)-4-(3-(2-cyano-1-((5-methyl-1H-imidazo[4,5-b]pyridin-2-yl)amino)ethyl)benzyl)piperidine-1-carboxylate
Descriptor: Phosphopantetheine adenylyltransferase, SULFATE ION, TETRAETHYLENE GLYCOL, ...
Authors:Mamo, M, Appleton, B.A.
Deposit date:2018-02-22
Release date:2018-04-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity.
J. Med. Chem., 61, 2018
2NYM
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BU of 2nym by Molmil
Crystal Structure of Protein Phosphatase 2A (PP2A) with C-terminus truncated catalytic subunit
Descriptor: MANGANESE (II) ION, Protein phosphatase 2, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ...
Authors:Chen, Y, Xing, Y, Xu, Y, Chao, Y, Lin, Z, Jeffrey, P.D, Shi, Y.
Deposit date:2006-11-21
Release date:2006-12-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure of the Protein Phosphatase 2A Holoenzyme.
Cell(Cambridge,Mass.), 127, 2006
6CRU
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BU of 6cru by Molmil
CryoEM structure of human enterovirus D68 emptied particle (pH 7.2 and 4 degrees Celsius)
Descriptor: viral protein 1, viral protein 2, viral protein 3
Authors:Liu, Y, Rossmann, M.G.
Deposit date:2018-03-19
Release date:2018-12-19
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CS4
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BU of 6cs4 by Molmil
CryoEM structure of human enterovirus D68 A-particle (pH 5.5 and 33 degrees Celsius)
Descriptor: viral protein 1, viral protein 2, viral protein 3
Authors:Liu, Y, Rossmann, M.G.
Deposit date:2018-03-19
Release date:2018-12-19
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5UVN
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BU of 5uvn by Molmil
Structure of E. coli MCE protein PqiB, periplasmic domain
Descriptor: Paraquat-inducible protein B
Authors:Bhabha, G, Ekiert, D.C.
Deposit date:2017-02-20
Release date:2017-04-12
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Architectures of Lipid Transport Systems for the Bacterial Outer Membrane.
Cell, 169, 2017
6CS6
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BU of 6cs6 by Molmil
CryoEM structure of human enterovirus D68 A-particle (pH 5.5 and room temperature)
Descriptor: viral protein 1, viral protein 2, viral protein 3
Authors:Liu, Y, Rossmann, M.G.
Deposit date:2018-03-19
Release date:2018-12-19
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4ZDI
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BU of 4zdi by Molmil
Crystal structure of the M. tuberculosis CTP synthase PyrG (apo form)
Descriptor: CALCIUM ION, CTP synthase
Authors:Bellinzoni, M, Barilone, N, Alzari, P.M.
Deposit date:2015-04-17
Release date:2015-07-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG.
Chem.Biol., 22, 2015

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