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3GYQ
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BU of 3gyq by Molmil
Structure of the Thiostrepton-Resistance Methyltransferase S-adenosyl-L-methionine Complex
Descriptor: S-ADENOSYLMETHIONINE, rRNA (adenosine-2'-O-)-methyltransferase
Authors:Dunstan, M.S, Conn, G.L.
Deposit date:2009-04-04
Release date:2009-04-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of the thiostrepton-resistance methyltransferase-S-adenosyl-L-methionine complex and its interaction with ribosomal RNA
J.Biol.Chem., 284, 2009
6W3Z
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BU of 6w3z by Molmil
Crystal Structure of Brugia malayi Deoxyhypusine synthase (DHPS)
Descriptor: BMA-DHPS-1, isoform a, CHLORIDE ION, ...
Authors:Santiago, A.S, dos Reis, C.V, Ramos, P.Z, Klippel, H.A, Silva, S.F, Zanelli, C.F, Massirer, K.B, Arruda, P, Edwards, A.M, Counago, R.M, Structural Genomics Consortium (SGC)
Deposit date:2020-03-09
Release date:2020-11-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural features and development of an assay platform of the parasite target deoxyhypusine synthase of Brugia malayi and Leishmania major.
Plos Negl Trop Dis, 14, 2020
3GXL
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BU of 3gxl by Molmil
ALK-5 kinase complex with GW857175
Descriptor: N-1H-indazol-5-yl-2-(6-methylpyridin-2-yl)quinazolin-4-amine, TGF-beta receptor type-1
Authors:Smith, W, Janson, C.
Deposit date:2009-04-02
Release date:2009-04-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design of novel quinazoline derivatives and related analogues as potent and selective ALK5 inhibitors
Bioorg.Med.Chem.Lett., 19, 2009
4V4I
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BU of 4v4i by Molmil
Crystal Structure of a 70S Ribosome-tRNA Complex Reveals Functional Interactions and Rearrangements.
Descriptor: 16S SMALL SUBUNIT RIBOSOMAL RNA, 23S LARGE SUBUNIT RIBOSOMAL RNA, 30S ribosomal protein S10, ...
Authors:Korostelev, A, Trakhanov, S, Laurberg, M, Noller, H.F.
Deposit date:2007-02-15
Release date:2014-07-09
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.71 Å)
Cite:Crystal Structure of a 70S Ribosome-tRNA Complex Reveals Functional Interactions and Rearrangements
Cell(Cambridge,Mass.), 126, 2006
3GK3
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BU of 3gk3 by Molmil
Crystal structure of acetoacetyl-CoA reductase from Burkholderia pseudomallei 1710b
Descriptor: Acetoacetyl-CoA reductase, PHOSPHATE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-03-09
Release date:2009-03-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
4V5Y
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BU of 4v5y by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with paromomycin and ribosome recycling factor (RRF).
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
Deposit date:2007-06-19
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.45 Å)
Cite:Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
6W7P
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BU of 6w7p by Molmil
Crystal Structure Analysis of Space-grown Lysozyme - Ground experiment
Descriptor: CHLORIDE ION, Lysozyme, SODIUM ION
Authors:Fernandez, D, Russi, S.
Deposit date:2020-03-19
Release date:2020-04-29
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Protein structural changes on a CubeSat under rocket acceleration profile.
NPJ Microgravity, 6, 2020
3GKN
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BU of 3gkn by Molmil
Insights into the Alkyl Peroxide Reduction Activity of Xanthomonas campestris Bacterioferritin Comigratory Protein from the Trapped Intermediate/Ligand Complex Structures
Descriptor: Bacterioferritin comigratory protein, GLYCEROL, NAPHTHALENE-2,6-DISULFONIC ACID, ...
Authors:Liao, S.-J.
Deposit date:2009-03-11
Release date:2009-06-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Insights into the alkyl peroxide reduction pathway of Xanthomonas campestris bacterioferritin comigratory protein from the trapped intermediate-ligand complex structures
J.Mol.Biol., 390, 2009
3GLA
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BU of 3gla by Molmil
Crystal Structure of the hspA from Xanthomonas axonopodis
Descriptor: Low molecular weight heat shock protein, PHOSPHATE ION
Authors:Hilario, E, Medrano, F.J, Bertolini, M.C.
Deposit date:2009-03-11
Release date:2009-03-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystallization and preliminary X-ray diffraction analysis of XAC1151, a small heat-shock protein from Xanthomonas axonopodis pv. citri belonging to the alpha-crystallin family
Acta Crystallogr.,Sect.F, 62, 2006
3H58
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BU of 3h58 by Molmil
Myoglobin Cavity Mutant H64LV68N Met form
Descriptor: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Soman, J, Olson, J.S.
Deposit date:2009-04-21
Release date:2009-05-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Optical detection of disordered water within a protein cavity.
J.Am.Chem.Soc., 131, 2009
3GK1
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BU of 3gk1 by Molmil
X-ray structure of bovine SBi132,Ca(2+)-S100B
Descriptor: 2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide, CACODYLATE ION, CALCIUM ION, ...
Authors:Charpentier, T.H, Weber, D.J, Toth, E.A.
Deposit date:2009-03-09
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography.
Biochemistry, 48, 2009
3GKF
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BU of 3gkf by Molmil
Crystal Structure of E. coli LsrF
Descriptor: Aldolase lsrF
Authors:Miller, S.T, Diaz, Z.C.
Deposit date:2009-03-10
Release date:2009-09-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of the Escherichia coli autoinducer-2 processing protein LsrF.
Plos One, 4, 2009
3GQ4
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BU of 3gq4 by Molmil
Sequence-matched MutM Lesion Recognition Complex 5 (LRC5)
Descriptor: DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*GP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3'), DNA glycosylase, ...
Authors:Spong, M.C, Qi, Y, Verdine, G.L.
Deposit date:2009-03-23
Release date:2009-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme.
Nature, 462, 2009
3GQI
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BU of 3gqi by Molmil
Crystal Structure of activated receptor tyrosine kinase in complex with substrates
Descriptor: Basic fibroblast growth factor receptor 1, DECAVANADATE, MAGNESIUM ION, ...
Authors:Bae, J.H, Lew, E.D, Yuzawa, S, Tome, F, Lax, I, Schlessinger, J.
Deposit date:2009-03-24
Release date:2009-08-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site.
Cell(Cambridge,Mass.), 138, 2009
3GN6
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BU of 3gn6 by Molmil
Crystal structure of CT0912, ORFan protein from Chlorobium tepidum with a ferredoxin-like domain repeat (NP_661805.1) from CHLOROBIUM TEPIDUM TLS at 1.80 A resolution
Descriptor: CT0912, ORFan protein with a ferredoxin-like domain repeat, DI(HYDROXYETHYL)ETHER, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2009-03-16
Release date:2009-03-31
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of CT0912, ORFan protein from Chlorobium tepidum with a ferredoxin-like domain repeat (NP_661805.1) from CHLOROBIUM TEPIDUM TLS at 1.80 A resolution
To be published
3GNQ
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BU of 3gnq by Molmil
Crystal structure of glyceraldehyde-3-phosphate dehydrogenase, type I from Burkholderia pseudomallei
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase, type I, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-03-17
Release date:2009-03-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of glyceraldehyde-3-phosphate dehydrogenase, type I from Burkholderia pseudomallei
TO BE PUBLISHED
3GQX
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BU of 3gqx by Molmil
Pyrococcus Horikoshii NOP5 RNA Binding Domain from a twinned crystal form
Descriptor: IODIDE ION, NOP5P PROTEIN
Authors:Reyes, F.E, Hardin, J.W, Batey, R.T.
Deposit date:2009-03-24
Release date:2009-04-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Analysis of a Critical Interaction within the Archaeal Box C/D Small Ribonucleoprotein Complex
J.Biol.Chem., 284, 2009
6W0T
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BU of 6w0t by Molmil
Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments
Descriptor: 6-(2-methylpropyl)-2-oxidanylidene-5~{H}-pyrimidine-4-carboxylic acid, Non-structural protein 3
Authors:Wu, M, Zhang, S.
Deposit date:2020-03-02
Release date:2021-01-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design.
Plos One, 16, 2021
6W5A
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BU of 6w5a by Molmil
Crystal Structure of the Fab fragment of humanized 5c8 antibody containing the fluorescent non-canonical amino acid L-(7-hydroxycoumarin-4-yl)ethylglycine at pH 9.7
Descriptor: Antibody 5c8* Fab Heavy Chain, Antibody 5c8* Fab Light Chain
Authors:Henderson, J.N, Simmons, C.R, Mills, J.H.
Deposit date:2020-03-12
Release date:2020-12-23
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Insights into How Protein Environments Tune the Spectroscopic Properties of a Noncanonical Amino Acid Fluorophore.
Biochemistry, 59, 2020
3GUA
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BU of 3gua by Molmil
Sulfates bound in the vestibule of AChBP
Descriptor: SULFATE ION, Soluble acetylcholine receptor
Authors:Hansen, S.B, Taylor, P.
Deposit date:2009-03-28
Release date:2009-07-14
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:An Ion Selectivity Filter in the Extracellular Domain of Cys-loop Receptors Reveals Determinants for Ion Conductance
J.Biol.Chem., 283, 2008
3GVV
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BU of 3gvv by Molmil
Single-chain UROD Y164G (GY) mutation
Descriptor: Uroporphyrinogen decarboxylase
Authors:Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P.
Deposit date:2009-03-31
Release date:2009-07-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen.
J.Mol.Biol., 389, 2009
4V4Z
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BU of 4v4z by Molmil
70S Thermus thermophilous ribosome functional complex with mRNA and E- and P-site tRNAs at 4.5A.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Jenner, L, Yusupova, G, Rees, B, Moras, D, Yusupov, M.
Deposit date:2006-06-27
Release date:2014-07-09
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (4.51 Å)
Cite:Structural basis for messenger RNA movement on the ribosome.
Nature, 444, 2006
3GWV
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BU of 3gwv by Molmil
Leucine transporter LeuT in complex with R-fluoxetine
Descriptor: (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, LEUCINE, SODIUM ION, ...
Authors:Zhou, Z, Zhen, J, Karpowich, N.K, Law, C.J, Reith, M.E.A, Wang, D.N.
Deposit date:2009-04-01
Release date:2009-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures.
Nat.Struct.Mol.Biol., 16, 2009
6W8M
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BU of 6w8m by Molmil
Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments
Descriptor: 2-oxo-1,2-dihydroquinazoline-4-carboxylic acid, Nonstructural polyprotein
Authors:Zhang, S, Garzan, A, Pathak, A.K, Augelli-Szafran, C.E, Wu, M.
Deposit date:2020-03-20
Release date:2021-01-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design.
Plos One, 16, 2021
4V53
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BU of 4v53 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin.
Descriptor: (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 16S rRNA, 23S rRNA, ...
Authors:Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
Deposit date:2007-06-16
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.54 Å)
Cite:Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007

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