6W3Z

Crystal Structure of Brugia malayi Deoxyhypusine synthase (DHPS)

Summary for 6W3Z

• Entry DOI: 10.2210/pdb6w3z/pdb
• Descriptor: BMA-DHPS-1, isoform a, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GLYCEROL, ... (5 entities in total)
• Functional Keywords: brugia malayi, deoxyhypusine synthase, structural genomics consortium, sgc, transferase
• Biological source: Brugia malayi (Filarial nematode worm)
• Total number of polymer chains: 4
• Total formula weight: 167011.40

Authors

Santiago, A.S.,dos Reis, C.V.,Ramos, P.Z.,Klippel, H.A.,Silva, S.F.,Zanelli, C.F.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Counago, R.M.,Structural Genomics Consortium (SGC) (deposition date: 2020-03-09, release date: 2020-11-04, Last modification date: 2023-10-18)

• Primary citation: Silva, S.F.,Klippel, A.H.,Ramos, P.Z.,Santiago, A.D.S.,Valentini, S.R.,Bengtson, M.H.,Massirer, K.B.,Bilsland, E.,Counago, R.M.,Zanelli, C.F.; Structural features and development of an assay platform of the parasite target deoxyhypusine synthase of Brugia malayi and Leishmania major.; Plos Negl Trop Dis, 14:e0008762-e0008762, 2020; PubMed: 33044977; DOI: 10.1371/journal.pntd.0008762

Experimental method

X-RAY DIFFRACTION (2.3 Å)