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1TFO
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Ribonuclease from Escherichia coli complexed with its inhibitor protein
Descriptor: Colicin D, Colicin D immunity protein
Authors:Yajima, S, Nakanishi, K, Takahashi, K, Ogawa, T, Kezuka, Y, Hidaka, M, Nonaka, T, Ohsawa, K, Masaki, H.
Deposit date:2004-05-27
Release date:2005-03-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Relation between tRNase activity and the structure of colicin D according to X-ray crystallography
Biochem.Biophys.Res.Commun., 322, 2004
1TFP
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TRANSTHYRETIN (FORMERLY KNOWN AS PREALBUMIN)
Descriptor: SULFATE ION, TRANSTHYRETIN
Authors:Sunde, M, Richardson, S.J, Chang, L, Pettersson, T.M, Schreiber, G, Blake, C.C.F.
Deposit date:1996-01-05
Release date:1996-06-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of transthyretin from chicken.
Eur.J.Biochem., 236, 1996
1TFQ
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NMR Structure of an Antagonists of the XIAP-Caspase-9 Interaction Complexed to the BIR3 domain of XIAP
Descriptor: Baculoviral IAP repeat-containing protein 4, N-METHYLALANYL-3-METHYLVALYL-N-(1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PROLINAMIDE, ZINC ION
Authors:Oost, T.K, Sun, C, Armstrong, R.C, Al-Assaad, A.S, Betz, S.F, Deckwerth, T.L, Elmore, S.W, Meadows, R.P, Olejniczak, E.T, Oleksijew, A, Oltersdorf, T, Rosenberg, S.H, Shoemaker, A.R, Zou, H, Fesik, S.W.
Deposit date:2004-05-27
Release date:2004-09-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Discovery of Potent Antagonists of the Antiapoptotic Protein XIAP for the Treatment of Cancer.
J.Med.Chem., 47, 2004
1TFR
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RNASE H FROM BACTERIOPHAGE T4
Descriptor: MAGNESIUM ION, T4 RNASE H
Authors:Mueser, T.C, Nossal, N.G, Hyde, C.C.
Deposit date:1996-04-27
Release date:1996-11-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structure of bacteriophage T4 RNase H, a 5' to 3' RNA-DNA and DNA-DNA exonuclease with sequence similarity to the RAD2 family of eukaryotic proteins.
Cell(Cambridge,Mass.), 85, 1996
1TFS
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NMR AND RESTRAINED MOLECULAR DYNAMICS STUDY OF THE THREE-DIMENSIONAL SOLUTION STRUCTURE OF TOXIN FS2, A SPECIFIC BLOCKER OF THE L-TYPE CALCIUM CHANNEL, ISOLATED FROM BLACK MAMBA VENOM
Descriptor: TOXIN FS2
Authors:Albrand, J.-P, Blackledge, M.J, Pascaud, F, Hollecker, M, Marion, D.
Deposit date:1995-01-26
Release date:1995-03-31
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:NMR and restrained molecular dynamics study of the three-dimensional solution structure of toxin FS2, a specific blocker of the L-type calcium channel, isolated from black mamba venom.
Biochemistry, 34, 1995
1TFT
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NMR Structure of an Antagonists of the XIAP-Caspase-9 Interaction Complexed to the BIR3 domain of XIAP
Descriptor: 1-[3,3-DIMETHYL-2-(2-METHYLAMINO-PROPIONYLAMINO)-BUTYRYL]-4-PHENOXY-PYRROLIDINE-2-CARBOXYLIC ACID(1,2,3,4-TETRAHYDRO-NAPHTHALEN-1-YL)-AMIDE, Baculoviral IAP repeat-containing protein 4, ZINC ION
Authors:Oost, T.K, Sun, C, Armstrong, R.C, Al-Assaad, A.S, Betz, S.F, Deckwerth, T.L, Elmore, S.W, Meadows, R.P, Olejniczak, E.T, Oleksijew, A.K, Oltersdorf, T, Rosenberg, S.H, Shoemaker, A.R, Zou, H, Fesik, S.W.
Deposit date:2004-05-27
Release date:2005-05-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer.
J.Med.Chem., 47, 2004
1TFU
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phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis
Descriptor: Phosphopantetheine adenylyltransferase
Authors:Morris, V.K, Izard, T, TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-05-27
Release date:2004-09-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Substrate-induced asymmetry and channel closure revealed by the apoenzyme structure of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase.
Protein Sci., 13, 2004
1TFV
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CRYSTAL STRUCTURE OF A BUFFALO SIGNALING GLYCOPROTEIN (SPB-40) SECRETED DURING INVOLUTION
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, mammary gland protein 40
Authors:Bilgrami, S, Saravanan, K, Yadav, S, Kaur, P, Srinivasan, A, Singh, T.P.
Deposit date:2004-05-27
Release date:2004-07-13
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:CRYSTAL STRUCTURE OF A BUFFALO SIGNALING GLYCOPROTEIN (SPB-40) SECRETED DURING INVOLUTION
To be Published
1TFW
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How CCA is added to the 3' end of immature tRNA without the use of an oligonucleotide template
Descriptor: 5'-R(*CP*GP*CP*GP*GP*AP*UP*CP*CP*GP*CP*AP*C)-3', 5'-R(*GP*CP*GP*GP*AP*CP*CP*CP*GP*CP*AP*C)-3', 5'-R(*GP*CP*GP*GP*AP*UP*CP*CP*GP*CP*AP*C)-3', ...
Authors:Xiong, Y, Steitz, T.A.
Deposit date:2004-05-27
Release date:2004-08-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template.
Nature, 430, 2004
1TFX
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COMPLEX OF THE SECOND KUNITZ DOMAIN OF TISSUE FACTOR PATHWAY INHIBITOR WITH PORCINE TRYPSIN
Descriptor: CALCIUM ION, TISSUE FACTOR PATHWAY INHIBITOR, TRYPSIN
Authors:Stubbs, M.T, Huber, R.
Deposit date:1997-01-21
Release date:1998-01-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa.
J.Mol.Biol., 269, 1997
1TFY
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How CCA is added to the 3' end of immature tRNA without the use of an oligonucleotide template
Descriptor: 5'-R(*CP*GP*CP*GP*GP*AP*UP*C)-3', 5'-R(*CP*GP*GP*AP*UP*CP*CP*GP*CP*AP*C)-3', 5'-R(*GP*CP*GP*GP*AP*UP*AP*UP*CP*CP*GP*CP*AP*C)-3', ...
Authors:Xiong, Y, Steitz, T.A.
Deposit date:2004-05-27
Release date:2004-08-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template.
Nature, 430, 2004
1TFZ
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Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and mammalian 4-hydroxyphenylpyruvate dioxygenases
Descriptor: (1-TERT-BUTYL-5-HYDROXY-1H-PYRAZOL-4-YL)[6-(METHYLSULFONYL)-4'-METHOXY-2-METHYL-1,1'-BIPHENYL-3-YL]METHANONE, 4-hydroxyphenylpyruvate dioxygenase, FE (III) ION
Authors:Yang, C, Pflugrath, J.W, Camper, D.L, Foster, M.L, Pernich, D.J, Walsh, T.A.
Deposit date:2004-05-27
Release date:2004-08-17
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and Mammalian 4-hydroxyphenylpyruvate dioxygenases
Biochemistry, 43, 2004
1TG0
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0.97-A structure of the SH3 domain of bbc1
Descriptor: Myosin tail region-interacting protein MTI1
Authors:Kursula, P, Kursula, I, Lehmann, F, Song, Y.H, Wilmanns, M.
Deposit date:2004-05-28
Release date:2005-06-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Saccharomyces cerevisiae SH3 domain structural genomics
To be Published
1TG1
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Crystal Structure of the complex formed between russells viper phospholipase A2 and a designed peptide inhibitor PHQ-Leu-Val-Arg-Tyr at 1.2A resolution
Descriptor: ACETIC ACID, METHANOL, Phospholipase A2, ...
Authors:Singh, N, Kaur, P, Somvanshi, R.K, Sharma, S, Dey, S, Perbandt, M, Betzel, C, Singh, T.P.
Deposit date:2004-05-28
Release date:2004-06-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal Structure of the complex formed between russells viper phospholipase A2 and a designed peptide inhibitor Cbz-dehydro-Leu-Val-Arg-Tyr at 1.2A resolution
To be Published
1TG2
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Crystal structure of phenylalanine hydroxylase A313T mutant with 7,8-dihydrobiopterin bound
Descriptor: 2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-7,8-DIHYDRO-6H-PTERIDIN-4-ONE, FE (III) ION, Phenylalanine-4-hydroxylase
Authors:Erlandsen, H, Pey, A.L, Gamez, A, Perez, B, Desviat, L.R, Aguado, C, Koch, R, Surendran, S, Tyring, S, Matalon, R, Scriver, C.R, Ugarte, M, Martinez, A, Stevens, R.C.
Deposit date:2004-05-28
Release date:2004-11-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1TG3
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Effect of Shuttle Location and pH Environment on H+ Transfer in Human Carbonic Anhydrase II
Descriptor: Carbonic anhydrase II, SULFATE ION, ZINC ION
Authors:Fisher, Z, Hernandez Prada, J.A, Tu, C.K, Duda, D, Yoshioka, C, An, H, Govindasamy, L, Silverman, D.N, McKenna, R.
Deposit date:2004-05-28
Release date:2005-01-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Kinetic Characterization of Active-Site Histidine as a Proton Shuttle in Catalysis by Human Carbonic Anhydrase II
Biochemistry, 44, 2005
1TG4
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Design of specific inhibitors of groupII phospholipase A2(PLA2): Crystal structure of the complex formed between russells viper PLA2 and designed peptide Phe-Leu-Ala-Tyr-Lys at 1.7A resolution
Descriptor: FLAYK peptide, Phospholipase A2, SULFATE ION
Authors:Singh, N, Somvanshi, R.K, Sharma, S, Dey, S, Perbandt, M, Betzel, C, Ethayathulla, A.S, Singh, T.P.
Deposit date:2004-05-28
Release date:2004-06-08
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Design of specific inhibitors of groupII phospholipase A2(PLA2): Crystal structure of the complex formed between russells viper PLA2 and designed peptide Phe-Leu-Ala-Tyr-Lys at 1.7A resolution
TO BE PUBLISHED
1TG5
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BU of 1tg5 by Molmil
Crystal structures of plant 4-hydroxyphenylpyruvate dioxygenases complexed with DAS645
Descriptor: 4-hydroxyphenylpyruvate dioxygenase, FE (II) ION, [1-TERT-BUTYL-3-(2,4-DICHLOROPHENYL)-5-HYDROXY-1H-PYRAZOL-4-YL][2-CHLORO-4-(METHYLSULFONYL)PHENYL]METHANONE
Authors:Yang, C, Pflugrath, J.W, Camper, D.L, Foster, M.L, Pernich, D.J, Walsh, T.A.
Deposit date:2004-05-28
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and Mammalian 4-hydroxyphenylpyruvate dioxygenases
Biochemistry, 43, 2004
1TG6
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Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP
Descriptor: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, GLYCEROL, ...
Authors:Kang, S.G, Maurizi, M.R, Thompson, M, Mueser, T, Ahvazi, B.
Deposit date:2004-05-28
Release date:2005-03-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP
J.Struct.Biol., 148, 2004
1TG7
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Native structure of beta-galactosidase from Penicillium sp.
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rojas, A.L, Nagem, R.A.P, Neustroev, K.N, Arand, M, Adamska, M, Eneyskaya, E.V, Kulminskaya, A.A, Garratt, R.C, Golubev, A.M, Polikarpov, I.
Deposit date:2004-05-28
Release date:2004-11-02
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structures of beta-Galactosidase from Penicillium sp. and its Complex with Galactose
J.Mol.Biol., 343, 2004
1TG8
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The structure of Dengue virus E glycoprotein
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, envelope glycoprotein
Authors:Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Rossmann, M.G.
Deposit date:2004-05-28
Release date:2004-09-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Conformational changes of the flavivirus e glycoprotein
Structure, 12, 2004
1TG9
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Effect of Shuttle Location and pH Environment on H+ Transfer in Human Carbonic Anhydrase II
Descriptor: Carbonic anhydrase II, ZINC ION
Authors:Fisher, Z, Hernandez Prada, J.A, Tu, C.K, Duda, D, Yoshioka, C, An, H, Govindasamy, L, Silverman, D.N, McKenna, R.
Deposit date:2004-05-28
Release date:2005-01-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Kinetic Characterization of Active-Site Histidine as a Proton Shuttle in Catalysis by Human Carbonic Anhydrase II
Biochemistry, 44, 2005
1TGB
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BU of 1tgb by Molmil
CRYSTAL STRUCTURE OF BOVINE TRYPSINOGEN AT 1.8 ANGSTROMS RESOLUTION. II. CRYSTALLOGRAPHIC REFINEMENT, REFINED CRYSTAL STRUCTURE AND COMPARISON WITH BOVINE TRYPSIN
Descriptor: CALCIUM ION, TRYPSINOGEN
Authors:Bode, W, Fehlhammer, H, Huber, R.
Deposit date:1979-03-07
Release date:1979-06-13
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of bovine trypsinogen at 1-8 A resolution. II. Crystallographic refinement, refined crystal structure and comparison with bovine trypsin.
J.Mol.Biol., 111, 1977
1TGC
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BU of 1tgc by Molmil
ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY
Descriptor: CALCIUM ION, TRYPSINOGEN
Authors:Walter, J, Steigemann, W, Singh, T.P, Bartunik, H, Bode, W, Huber, R.
Deposit date:1981-10-26
Release date:1982-03-04
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography
Acta Crystallogr.,Sect.B, 38, 1982
1TGE
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BU of 1tge by Molmil
The structure of immature Dengue virus at 12.5 angstrom
Descriptor: envelope glycoprotein
Authors:Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Kuhn, R.J, Rossmann, M.G.
Deposit date:2004-05-28
Release date:2004-09-28
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (12.5 Å)
Cite:Conformational changes of the flavivirus e glycoprotein.
Structure, 12, 2004

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