1TG6

Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP

Summary for 1TG6

• Entry DOI: 10.2210/pdb1tg6/pdb
• Related: 1TYF
• Descriptor: Putative ATP-dependent Clp protease proteolytic subunit, 1,4-DIETHYLENE DIOXIDE, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: mitochondrial clpp, clp/hsp 100, atp-dependent protease, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion matrix : Q16740
• Total number of polymer chains: 7
• Total formula weight: 214309.43

Authors

Kang, S.G.,Maurizi, M.R.,Thompson, M.,Mueser, T.,Ahvazi, B. (deposition date: 2004-05-28, release date: 2005-03-22, Last modification date: 2023-08-23)

• Primary citation: Kang, S.G.,Maurizi, M.R.,Thompson, M.,Mueser, T.,Ahvazi, B.; Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP; J.Struct.Biol., 148:338-352, 2004; PubMed: 15522782; DOI: 10.1016/j.jsb.2004.07.004

Experimental method

X-RAY DIFFRACTION (2.1 Å)