1TG3
Effect of Shuttle Location and pH Environment on H+ Transfer in Human Carbonic Anhydrase II
Summary for 1TG3
Entry DOI | 10.2210/pdb1tg3/pdb |
Related | 1T9N 1TB0 1TBT 1TE3 1TEQ 1TEU 1TG9 1TH9 1THK |
Descriptor | Carbonic anhydrase II, ZINC ION, SULFATE ION, ... (4 entities in total) |
Functional Keywords | proton shuttle carbonic anhydrase metalloenzyme, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29474.58 |
Authors | Fisher, Z.,Hernandez Prada, J.A.,Tu, C.K.,Duda, D.,Yoshioka, C.,An, H.,Govindasamy, L.,Silverman, D.N.,McKenna, R. (deposition date: 2004-05-28, release date: 2005-01-25, Last modification date: 2023-08-23) |
Primary citation | Fisher, Z.,Hernandez Prada, J.A.,Tu, C.K.,Duda, D.,Yoshioka, C.,An, H.,Govindasamy, L.,Silverman, D.N.,McKenna, R. Structural and Kinetic Characterization of Active-Site Histidine as a Proton Shuttle in Catalysis by Human Carbonic Anhydrase II Biochemistry, 44:1097-1105, 2005 Cited by PubMed: 15667203DOI: 10.1021/bi0480279 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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