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1TB0

Effect of Shuttle Location and pH Environment on H+ Transfer in Human Carbonic Anhydrase II

Summary for 1TB0
Entry DOI10.2210/pdb1tb0/pdb
Related1T9N 1TBT 1TE3 1TEQ 1TEU
DescriptorCarbonic anhydrase II, ZINC ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywordsproton shuttle carbonic anhydrase metalloenzyme, lyase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm : P00918
Total number of polymer chains1
Total formula weight29389.92
Authors
Fisher, Z.,Hernandez Prada, J.A.,Tu, C.,Duda, D.,Yoshioka, C.,An, H.,Govindasamy, L.,Silverman, D.N.,McKenna, R. (deposition date: 2004-05-19, release date: 2005-01-25, Last modification date: 2023-08-23)
Primary citationFisher, Z.,Hernandez Prada, J.A.,Tu, C.,Duda, D.,Yoshioka, C.,An, H.,Govindasamy, L.,Silverman, D.N.,McKenna, R.
Structural and kinetic characterization of active-site histidine as a proton shuttle in catalysis by human carbonic anhydrase II.
Biochemistry, 44:1097-1105, 2005
Cited by
PubMed: 15667203
DOI: 10.1021/bi0480279
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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