7P4N
 
 | |
7OMK
 | | The NMR structure of the Zf-GRF domains from the mouse Endonuclease VIII-LIKE 3 (mNEIL3) | | Descriptor: | Endonuclease 8-like 3 | | Authors: | Dinesh, D.C, Huskova, A, Srb, P, Veverka, V, Silhan, J. | | Deposit date: | 2021-05-24 | | Release date: | 2022-06-01 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Model of abasic site DNA cross-link repair; from the architecture of NEIL3 DNA binding domains to the X-structure model.
Nucleic Acids Res., 50, 2022
|
|
7OLG
 | | EB1 bound to MACF peptide | | Descriptor: | 11MACF, Microtubule-associated protein RP/EB family member 1 | | Authors: | Almeida, T.B, Barsukov, I.L. | | Deposit date: | 2021-05-20 | | Release date: | 2022-06-01 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | EB1 bound to MACF peptide
To Be Published
|
|
7OSW
 | |
6XOR
 | |
8W4S
 | | Crystal structure of PDE5A in complex with CVT-313 | | Descriptor: | 2,2'-{[6-{[(4-methoxyphenyl)methyl]amino}-9-(propan-2-yl)-9H-purin-2-yl]azanediyl}di(ethan-1-ol), MAGNESIUM ION, ZINC ION, ... | | Authors: | Liu, J.Y, Li, M.J, Xu, Y.C. | | Deposit date: | 2023-08-24 | | Release date: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.848 Å) | | Cite: | Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors.
Eur.J.Med.Chem., 262, 2023
|
|
8W4T
 | | Crystal structure of PDE5A in complex with a novel inhibitor | | Descriptor: | 2-[bis(2-hydroxyethyl)amino]-6-[(4-methoxyphenyl)methylamino]-9-propan-2-yl-7~{H}-purin-8-one, MAGNESIUM ION, ZINC ION, ... | | Authors: | Liu, J.Y, Li, M.J, Xu, Y.C. | | Deposit date: | 2023-08-24 | | Release date: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.199 Å) | | Cite: | Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors.
Eur.J.Med.Chem., 262, 2023
|
|
7PJ1
 | |
2RLZ
 | | Solid-State MAS NMR structure of the dimer Crh | | Descriptor: | HPr-like protein crh | | Authors: | Loquet, A, Bardiaux, B, Gardiennet, C, Blanchet, C, Baldus, M, Nilges, M, Malliavin, T, Bockmann, A. | | Deposit date: | 2007-09-04 | | Release date: | 2008-06-17 | | Last modified: | 2024-05-29 | | Method: | SOLID-STATE NMR | | Cite: | 3D structure determination of the Crh protein from highly ambiguous solid-state NMR restraints.
J.Am.Chem.Soc., 130, 2008
|
|
8VSW
 | | 4-MERCAPTOPHENOL-ALPHA3C | | Descriptor: | 4-mercaptophenol-alpha3C protein, 4-sulfanylphenol | | Authors: | Tommos, C. | | Deposit date: | 2024-01-24 | | Release date: | 2024-03-27 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Switching the proton-coupled electron transfer mechanism for non-canonical tyrosine residues in a de novo protein.
Chem Sci, 15, 2024
|
|
8VZ4
 | |
8VU6
 | |
8VU8
 | |
7AET
 | |
7AEU
 | |
7AEV
 | |
8VU7
 | |
6H66
 | | CryoEM structure of the MDA5-dsRNA filament with 93 degree twist and without nucleotide | | Descriptor: | Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ... | | Authors: | Yu, Q, Qu, K, Modis, Y. | | Deposit date: | 2018-07-26 | | Release date: | 2018-11-21 | | Last modified: | 2020-11-18 | | Method: | ELECTRON MICROSCOPY (4.16 Å) | | Cite: | Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
|
|
7PMP
 | |
3MHZ
 | | 1.7A structure of 2-fluorohistidine labeled Protective Antigen | | Descriptor: | CALCIUM ION, Protective antigen, TETRAETHYLENE GLYCOL | | Authors: | Lovell, S, Battaile, K.P, Wimalasena, D.S, Janowiak, B.E, Miyagi, M, Sun, J, Hajduch, J, Pooput, C, Kirk, K.L, Bann, J.G. | | Deposit date: | 2010-04-09 | | Release date: | 2010-08-11 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Evidence that histidine protonation of receptor-bound anthrax protective antigen is a trigger for pore formation.
Biochemistry, 49, 2010
|
|
7PZ1
 | | Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH8535 | | Descriptor: | 1,2-ETHANEDIOL, 4-(4-bromanyl-2-oxidanylidene-3~{H}-benzimidazol-1-yl)-~{N}-(3-methoxy-4-methyl-phenyl)piperidine-1-carboxamide, GLYCEROL, ... | | Authors: | Scaletti, E.R, Helleday, T, Stenmark, P. | | Deposit date: | 2021-10-11 | | Release date: | 2022-11-02 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Optimization of N-Piperidinyl-Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8-Oxo-Guanine DNA Glycosylase 1.
Chemmedchem, 18, 2023
|
|
8VUR
 | | Human GluN1-2A with IgG 003-102 WT conformation | | Descriptor: | 003-102 Heavy, 003-102 Light, Glutamate receptor ionotropic, ... | | Authors: | Michalski, K, Furukawa, H. | | Deposit date: | 2024-01-29 | | Release date: | 2024-09-11 | | Last modified: | 2024-09-18 | | Method: | ELECTRON MICROSCOPY (3.84 Å) | | Cite: | Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
|
|
8YKX
 | | Cryo-EM structure of succinate receptor SUCR1 bound to maleic acid | | Descriptor: | Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Li, C, Liu, H, Li, J, Zhu, H, Fu, W, Xu, H.E. | | Deposit date: | 2024-03-05 | | Release date: | 2024-05-29 | | Last modified: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (2.69 Å) | | Cite: | Molecular basis of ligand recognition and activation of the human succinate receptor SUCR1.
Cell Res., 34, 2024
|
|
8WT5
 | |
6MIZ
 | |
