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8QQI
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E.coli DNA gyrase in complex with 217 bp substrate DNA and LEI-800
Descriptor: DNA gyrase subunit A, DNA gyrase subunit B, MAGNESIUM ION, ...
Authors:Ghilarov, D, Martin, N.I, van der Stelt, M.
Deposit date:2023-10-04
Release date:2024-06-19
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria.
Nat.Chem., 2024
6E8G
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BU of 6e8g by Molmil
CryoEM reconstruction of IST1-CHMP1B copolymer filament bound to ssDNA at 2.9 Angstrom resolution
Descriptor: Charged multivesicular body protein 1b, IST1 homolog
Authors:Talledge, N, Frost, A, McCullough, J.
Deposit date:2018-07-29
Release date:2018-08-15
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The ESCRT-III proteins IST1 and CHMP1B assemble around nucleic acids
Biorxiv, 2018
6OKW
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BU of 6okw by Molmil
Solution structure of VEK50
Descriptor: Plasminogen-binding group A streptococcal M-like protein PAM
Authors:Yuan, Y, Castellino, F.J.
Deposit date:2019-04-15
Release date:2020-02-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes.
J.Struct.Biol., 208, 2019
6I7C
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BU of 6i7c by Molmil
Dye type peroxidase Aa from Streptomyces lividans: imidazole complex
Descriptor: Deferrochelatase/peroxidase, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Moreno-Chicano, T, Ebrahim, A.E, Worrall, J.A.R, Strange, R.W, Axford, D, Sherrell, D.A, Sugimoto, H, Tono, K, Owada, S, Duyvesteyn, H.
Deposit date:2018-11-16
Release date:2019-11-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:High-throughput structures of protein-ligand complexes at room temperature using serial femtosecond crystallography.
Iucrj, 6, 2019
6OQ9
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BU of 6oq9 by Molmil
Solution structure of VEK50 in the bound form with plasminogen kringle 2
Descriptor: Plasminogen-binding group A streptococcal M-like protein PAM
Authors:Yuan, Y, Castellino, F.J.
Deposit date:2019-04-25
Release date:2019-07-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes.
J.Struct.Biol., 208, 2019
6OQP
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U-AITx-Ate1
Descriptor: SER-LYS-TRP-ILE-CYS-ALA-ASN-ARG-SER-VAL-CYS-PRO-ILE
Authors:Elnahriry, K.A, Wai, D.C.C, Norton, R.S.
Deposit date:2019-04-28
Release date:2019-07-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa.
Toxicon, 168, 2019
6OSW
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BU of 6osw by Molmil
An order-to-disorder structural switch activates the FoxM1 transcription factor
Descriptor: Forkhead box M1
Authors:Marceau, A.H, Rubin, S.M, Nerli, S, McShane, A.C, Sgourakis, N.G.
Deposit date:2019-05-02
Release date:2019-05-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:An order-to-disorder structural switch activates the FoxM1 transcription factor.
Elife, 8, 2019
6OKY
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BU of 6oky by Molmil
Solution structure of truncated peptide from PAMap53
Descriptor: Plasminogen-binding group A streptococcal M-like protein PAM
Authors:Yuan, Y, Castellino, F.J.
Deposit date:2019-04-15
Release date:2020-02-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes.
J.Struct.Biol., 208, 2019
6P5W
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BU of 6p5w by Molmil
Structure of DCN1 bound to 3-methyl-N-((4S,5S)-3-methyl-6-oxo-1-phenyl-4-(p-tolyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide
Descriptor: 3-methyl-N-[(4S,5S)-3-methyl-4-(4-methylphenyl)-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]benzamide, Lysozyme,DCN1-like protein 1 chimera
Authors:Guy, R.K, Kim, H.S, Hammill, J.T, Scott, D.C, Schulman, B.A.
Deposit date:2019-05-31
Release date:2019-09-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation.
J.Med.Chem., 62, 2019
6P6B
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BU of 6p6b by Molmil
CS-Rosetta Model of PEA-15 Death Effector Domain
Descriptor: Astrocytic phosphoprotein PEA-15
Authors:Wei, Y, Crespo Flores, S, Cabezas, A, Hassan, S.
Deposit date:2019-06-03
Release date:2019-07-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:PEA-15 C-Terminal Tail Allosterically Modulates Death-Effector Domain Conformation and Facilitates Protein-Protein Interactions.
Int J Mol Sci, 20, 2019
8S9S
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BU of 8s9s by Molmil
Structure of the human ER membrane protein complex (EMC) in GDN
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Tomaleri, G.P, Nguyen, V.N, Voorhees, R.M.
Deposit date:2023-03-30
Release date:2023-05-17
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A selectivity filter in the ER membrane protein complex limits protein misinsertion at the ER.
J.Cell Biol., 222, 2023
5XG7
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BU of 5xg7 by Molmil
Galectin-13/Placental Protein 13 crystal structure
Descriptor: Galactoside-binding soluble lectin 13
Authors:Su, J.Y, Wang, Y.
Deposit date:2017-04-12
Release date:2018-01-31
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Galectin-13, a different prototype galectin, does not bind beta-galacto-sides and forms dimers via intermolecular disulfide bridges between Cys-136 and Cys-138
Sci Rep, 8, 2018
6P6C
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BU of 6p6c by Molmil
CS-Rosetta Model of PEA-15 Death Effector Domain in the Complex with ERK2
Descriptor: Astrocytic phosphoprotein PEA-15
Authors:Wei, Y, Crespo Flores, S, Cabezas, A, Hassan, S.
Deposit date:2019-06-03
Release date:2019-07-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:PEA-15 C-Terminal Tail Allosterically Modulates Death-Effector Domain Conformation and Facilitates Protein-Protein Interactions.
Int J Mol Sci, 20, 2019
6EZN
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BU of 6ezn by Molmil
Cryo-EM structure of the yeast oligosaccharyltransferase (OST) complex
Descriptor: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wild, R, Kowal, J, Eyring, J, Ngwa, E.M, Aebi, M, Locher, K.P.
Deposit date:2017-11-16
Release date:2018-01-17
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular basis for glycan recognition and reaction priming of eukaryotic oligosaccharyltransferase.
Nat Commun, 13, 2022
6P9L
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BU of 6p9l by Molmil
Crystal structure of Mycobacterium tuberculosis KasA in complex with JFX
Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 1, 4-fluoro-N-(3-methyl-1H-indazol-5-yl)butane-1-sulfonamide, GLYCEROL, ...
Authors:Capodagli, G.C, Neiditch, M.B.
Deposit date:2019-06-10
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.305 Å)
Cite:A Preclinical Candidate Targeting Mycobacterium tuberculosis KasA.
Cell Chem Biol, 27, 2020
5X3Y
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BU of 5x3y by Molmil
Refined solution structure of musashi1 RBD2
Descriptor: RNA-binding protein Musashi homolog 1
Authors:Iwaoka, R, Nagata, T, Tsuda, K, Imai, T, Okano, H, Kobayashi, N, Katahira, M.
Deposit date:2017-02-09
Release date:2017-12-13
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Insight into the Recognition of r(UAG) by Musashi-1 RBD2, and Construction of a Model of Musashi-1 RBD1-2 Bound to the Minimum Target RNA
Molecules, 22, 2017
5XF4
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BU of 5xf4 by Molmil
Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (S,S-configuration)
Descriptor: (1S,2S)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ...
Authors:Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
Deposit date:2017-04-07
Release date:2017-10-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
6P9K
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BU of 6p9k by Molmil
Crystal structure of Mycobacterium tuberculosis KasA in complex with O6G
Descriptor: 3-oxoacyl-ACP synthase, GLYCEROL, ISOPROPYL ALCOHOL, ...
Authors:Capodagli, G.C, Neiditch, M.B.
Deposit date:2019-06-10
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.703 Å)
Cite:A Preclinical Candidate Targeting Mycobacterium tuberculosis KasA.
Cell Chem Biol, 27, 2020
5XQM
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BU of 5xqm by Molmil
NMR solution structure of SMO1, Sumo homologue in Caenorhabditis elegans
Descriptor: Small ubiquitin-related modifier
Authors:Gowda, C.M, Surana, P, Das, R.
Deposit date:2017-06-07
Release date:2017-11-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural and functional analysis of SMO-1, the SUMO homolog in Caenorhabditis elegans
PLoS ONE, 12, 2017
5XS1
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BU of 5xs1 by Molmil
Solution structure of Crustacean Hyperglycemic Hormone-like (CHH-L) from the Scylla Olivacea
Descriptor: Hyperglycemic hormone-like peptide
Authors:Chen, Y.R, Lyu, P.C.
Deposit date:2017-06-11
Release date:2018-06-13
Method:SOLUTION NMR
Cite:Solution structure of Crustacean Hyperglycemic Hormone-like (CHH-L) from the Scylla Olivacea
To Be Published
6PGE
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BU of 6pge by Molmil
WDR5delta32 bound to ethyl 3-(4-(hydroxymethyl)-1H-imidazol-2-yl)propanoate
Descriptor: 1,2-ETHANEDIOL, SULFATE ION, WD repeat-containing protein 5, ...
Authors:Dennis, M.L, Peat, T.S.
Deposit date:2019-06-24
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Fragment screening for a protein-protein interaction inhibitor to WDR5.
Struct Dyn., 6, 2019
5X7X
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BU of 5x7x by Molmil
The crystal structure of the nucleosome containing H3.3 at 2.18 angstrom resolution
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
Authors:Arimura, Y, Taguchi, H, Kurumizaka, H.
Deposit date:2017-02-27
Release date:2017-04-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.184 Å)
Cite:Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8
Biochemistry, 56, 2017
8PK7
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BU of 8pk7 by Molmil
Helical reconstruction of CHIKV nsP3 helical scaffolds
Descriptor: Non-structural protein 3, ZINC ION
Authors:Reguera, J, Hons, M, Zimberger, C, Ptchelkine, D, Jones, R, Desfosses, A.
Deposit date:2023-06-25
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (2.52 Å)
Cite:The alphavirus nsP3 protein forms helical tubular scaffolds important for viral replication and particle assembly
To Be Published
8PHZ
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BU of 8phz by Molmil
Helical reconstruction of CHIKV nsP3 helical scaffolds
Descriptor: Non-structural protein 3, ZINC ION
Authors:Reguera, J, Hons, M, Zimberger, C, Ptchelkine, D, Jones, R, Desfosses, A.
Deposit date:2023-06-20
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (2.35 Å)
Cite:The alphavirus nsP3 protein forms helical tubular scaffolds important for viral replication and particle assembly
To be published
8QE8
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BU of 8qe8 by Molmil
Structure of the non-canonical CTLH E3 substrate receptor WDR26 bound to NMNAT1 substrate
Descriptor: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1, WD repeat-containing protein 26, ...
Authors:Chrustowicz, J, Sherpa, D, Schulman, B.A.
Deposit date:2023-08-30
Release date:2024-05-15
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism.
Mol.Cell, 84, 2024

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PDB entries from 2024-09-11

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