6UW6
| Cryo-EM structure of the human TRPV3 K169A mutant determined in lipid nanodisc | Descriptor: | Transient receptor potential cation channel subfamily V member 3, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | Authors: | Deng, Z, Yuan, P. | Deposit date: | 2019-11-04 | Release date: | 2020-07-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | Gating of human TRPV3 in a lipid bilayer. Nat.Struct.Mol.Biol., 27, 2020
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6VAB
| Mouse retromer sub-structure: VPS35/VPS35 flat dimer | Descriptor: | Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35 | Authors: | Kendall, A.K, Jackson, L.P. | Deposit date: | 2019-12-17 | Release date: | 2020-02-19 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Mammalian Retromer Is an Adaptable Scaffold for Cargo Sorting from Endosomes. Structure, 28, 2020
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6UOV
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4WU3
| Structure of the PTP-like myo-inositol phosphatase from Mitsuokella multacida in complex with myo-inositol-(1,3,4,5)-tetrakisphosphate | Descriptor: | GLYCEROL, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, MYO-INOSITOL PHOSPHOHYDROLASE, ... | Authors: | Bruder, L.M, Mosimann, S.C. | Deposit date: | 2014-10-30 | Release date: | 2015-12-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the PTP-like phytase from Selenomonas ruminantium in complex with myo-inositol-(1,3,4,5)-tetrakisphosphate To Be Published
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4WVR
| Crystal structure of Dscam1 Ig7 domain, isoform 5 | Descriptor: | Down syndrome cell adhesion molecule, isoform AK | Authors: | Chen, Q, Yu, Y, Li, S, Cheng, L. | Deposit date: | 2014-11-07 | Release date: | 2015-11-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.948 Å) | Cite: | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition Sci Adv, 2, 2016
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6VH7
| Doublet Tau Fibril from Corticobasal Degeneration Human Brain Tissue | Descriptor: | Microtubule-associated protein tau | Authors: | Arakhamia, T, Lee, C.E, Carlomagno, Y, Duong, D.M, Kundinger, S.R, Wang, K, Williams, D, DeTure, M, Dickson, D.W, Cook, C.N, Seyfried, N.T, Petrucelli, L, Fitzpatrick, A.W.P. | Deposit date: | 2020-01-09 | Release date: | 2020-03-04 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains. Cell, 180, 2020
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4V8W
| Structure and conformational variability of the Mycobacterium tuberculosis fatty acid synthase multienzyme complex | Descriptor: | FLAVIN MONONUCLEOTIDE, TYPE-I FATTY ACID SYNTHASE | Authors: | Ciccarelli, L, Connell, S.R, Enderle, M, Mills, D.J, Vonck, J, Grininger, M. | Deposit date: | 2013-04-18 | Release date: | 2014-07-09 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (17.5 Å) | Cite: | Structure and Conformational Variability of the Mycobacterium Tuberculosis Fatty Acid Synthase Multienzyme Complex. Structure, 21, 2013
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6UW9
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6UXW
| SWI/SNF nucleosome complex with ADP-BeFx | Descriptor: | 601 sequence bottom strand, 601 sequence top strand, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | He, Y, Han, Y. | Deposit date: | 2019-11-08 | Release date: | 2020-03-18 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (8.96 Å) | Cite: | Cryo-EM structure of SWI/SNF complex bound to a nucleosome. Nature, 579, 2020
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6UQE
| ClpA/ClpP Disengaged State bound to RepA-GFP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease proteolytic subunit, ... | Authors: | Lopez, K.L, Rizo, A.R, Southworth, D.R. | Deposit date: | 2019-10-18 | Release date: | 2020-04-22 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nat.Struct.Mol.Biol., 27, 2020
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6V0F
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 4 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6V0V
| Cryo-EM structure of mouse WT RAG1/2 NFC complex (DNA0) | Descriptor: | CALCIUM ION, DNA (30-MER), V(D)J recombination-activating protein 1, ... | Authors: | Chen, X, Yang, W, Gellert, M. | Deposit date: | 2019-11-19 | Release date: | 2020-01-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.61 Å) | Cite: | Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
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6V1X
| Cryo-EM Structure of the Hyperpolarization-Activated Potassium Channel KAT1: Tetramer | Descriptor: | (2S)-1-(nonanoyloxy)-3-(phosphonooxy)propan-2-yl tetradecanoate, (3beta,5beta,14beta,17alpha)-cholestan-3-ol, Potassium channel KAT1 | Authors: | Clark, M.D, Contreras, G.F, Shen, R, Perozo, E. | Deposit date: | 2019-11-21 | Release date: | 2020-06-03 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Electromechanical coupling in the hyperpolarization-activated K + channel KAT1. Nature, 583, 2020
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6UUM
| Crystal structure of antibody 438-B11 DSS mutant (Cys98A-Cys100aA) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, B11 DSS Fab Heavy Chain, ... | Authors: | Kumar, S, Wilson, I.A. | Deposit date: | 2019-10-30 | Release date: | 2020-09-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A V H 1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite. Sci Adv, 6, 2020
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6UPH
| Structure of a Yeast Centromeric Nucleosome at 2.7 Angstrom resolution | Descriptor: | DNA (119-MER), Histone H2A, Histone H2B.1, ... | Authors: | Migl, D, Kschonsak, M, Arthur, C.P, Khin, Y, Harrison, S.C, Ciferri, C, Dimitrova, Y.N. | Deposit date: | 2019-10-17 | Release date: | 2019-11-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryoelectron Microscopy Structure of a Yeast Centromeric Nucleosome at 2.7 angstrom Resolution. Structure, 28, 2020
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4WLY
| High pressure protein crystallography of hen egg white lysozyme at 380 MPa | Descriptor: | CHLORIDE ION, Lysozyme C, SODIUM ION | Authors: | Yamada, H, Nagae, T, Watanabe, N. | Deposit date: | 2014-10-08 | Release date: | 2015-04-08 | Last modified: | 2020-02-05 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | High-pressure protein crystallography of hen egg-white lysozyme Acta Crystallogr.,Sect.D, 71, 2015
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4WM4
| High pressure protein crystallography of hen egg white lysozyme at 800 MPa | Descriptor: | CHLORIDE ION, Lysozyme C, SODIUM ION | Authors: | Yamada, H, Nagae, T, Watanabe, N. | Deposit date: | 2014-10-08 | Release date: | 2015-04-08 | Last modified: | 2020-02-05 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | High-pressure protein crystallography of hen egg-white lysozyme Acta Crystallogr.,Sect.D, 71, 2015
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4WPO
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G in the pre-translocational state | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Lin, J, Gagnon, M.G, Steitz, T.A. | Deposit date: | 2014-10-20 | Release date: | 2015-01-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation. Cell, 160, 2015
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4X4E
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4V7E
| Model of the small subunit RNA based on a 5.5 A cryo-EM map of Triticum aestivum translating 80S ribosome | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S10E, ... | Authors: | Barrio-Garcia, C, Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R. | Deposit date: | 2013-11-22 | Release date: | 2014-07-09 | Last modified: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion. Nature, 506, 2014
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4X1K
| Discovery of cytotoxic Dolastatin 10 analogs with N-terminal modifications | Descriptor: | 2-methyl-L-alanyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl}-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Parris, K.D. | Deposit date: | 2014-11-24 | Release date: | 2015-03-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Discovery of cytotoxic dolastatin 10 analogues with N-terminal modifications. J.Med.Chem., 57, 2014
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4X4I
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4X5U
| X-ray crystal structure of CagL at pH 4.2 | Descriptor: | Cag pathogenicity island protein (Cag18) | Authors: | Sundberg, E.J, Bonsor, D.A, Diederichs, K. | Deposit date: | 2014-12-05 | Release date: | 2015-04-08 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Integrin Engagement by the Helical RGD Motif of the Helicobacter pylori CagL Protein Is Regulated by pH-induced Displacement of a Neighboring Helix. J.Biol.Chem., 290, 2015
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4X5Y
| Menin in complex with MI-503 | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-methyl-1-(1H-pyrazol-4-ylmethyl)-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile, ... | Authors: | Pollock, J, Borkin, D, Cierpicki, T, Grembecka, J. | Deposit date: | 2014-12-06 | Release date: | 2015-04-15 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo. Cancer Cell, 27, 2015
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4WNK
| Crystal Structure of Bovine G Protein Coupled-Receptor Kinase 5 in Complex with CCG215022 | Descriptor: | (4S)-4-{4-fluoro-3-[(pyridin-2-ylmethyl)carbamoyl]phenyl}-N-(1H-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide, G protein-coupled receptor kinase 5, SULFATE ION | Authors: | Homan, K.T, Tesmer, J.J.G. | Deposit date: | 2014-10-13 | Release date: | 2015-06-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Crystal Structure of G Protein-coupled Receptor Kinase 5 in Complex with a Rationally Designed Inhibitor. J.Biol.Chem., 290, 2015
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