5W3U
| Crystal structure of SsoPox AsB5 mutant (V27A-I76T-Y97W-Y99F-L130P-L226V) | Descriptor: | 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ... | Authors: | Hiblot, J, Gotthard, G, Jacquet, P, Daude, D, Bergonzi, C, Chabriere, E, Elias, M. | Deposit date: | 2017-06-08 | Release date: | 2017-12-20 | Last modified: | 2021-08-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase. Sci Rep, 7, 2017
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3B8S
| Crystal structure of wild-type chitinase A from Vibrio harveyi | Descriptor: | Chitinase A | Authors: | Songsiriritthigul, C, Pantoom, S, Aguda, A.H, Robinson, R.C, Suginta, W. | Deposit date: | 2007-11-01 | Release date: | 2008-04-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of Vibrio harveyi chitinase A complexed with chitooligosaccharides: implications for the catalytic mechanism J.Struct.Biol., 162, 2008
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5W13
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5W58
| Crystal Complex of Cyclooxygenase-2: (S)-ARN-2508 (a dual COX and FAAH inhibitor) | Descriptor: | (2S)-2-{2-fluoro-3'-[(hexylcarbamoyl)oxy][1,1'-biphenyl]-4-yl}propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Xu, S, Goodman, M.C, Banerjee, S, Piomelli, D, Marnett, L.J. | Deposit date: | 2017-06-14 | Release date: | 2018-01-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.267 Å) | Cite: | Dual cyclooxygenase-fatty acid amide hydrolase inhibitor exploits novel binding interactions in the cyclooxygenase active site. J. Biol. Chem., 293, 2018
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3S8F
| 1.8 A structure of ba3 cytochrome c oxidase from Thermus thermophilus in lipid environment | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, COPPER (II) ION, Cytochrome c oxidase polypeptide 2A, ... | Authors: | Tiefenbrunn, T, Liu, W, Chen, Y, Katritch, V, Stout, C.D, Fee, J.A, Cherezov, V. | Deposit date: | 2011-05-27 | Release date: | 2011-08-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | High resolution structure of the ba3 cytochrome c oxidase from Thermus thermophilus in a lipidic environment. Plos One, 6, 2011
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5VR8
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1BC8
| STRUCTURES OF SAP-1 BOUND TO DNA SEQUENCES FROM THE E74 AND C-FOS PROMOTERS PROVIDE INSIGHTS INTO HOW ETS PROTEINS DISCRIMINATE BETWEEN RELATED DNA TARGETS | Descriptor: | DNA (5'-D(*AP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*CP*GP*GP*AP*AP*GP*T)-3'), PROTEIN (SAP-1 ETS DOMAIN), ... | Authors: | Mo, Y, Vaessen, B, Johnston, K, Marmorstein, R. | Deposit date: | 1998-05-05 | Release date: | 1998-12-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins. Mol.Cell, 2, 1998
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3CKH
| Crystal structure of Eph A4 receptor | Descriptor: | Ephrin type-A receptor 4 | Authors: | Shi, J.H, Song, J.X. | Deposit date: | 2008-03-15 | Release date: | 2008-09-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 Receptor. J.Biol.Chem., 283, 2008
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3SBU
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1W1S
| Plant Cytokinin Dehydrogenase in Complex with Benzylaminopurine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYTOKININ DEHYDROGENASE, ... | Authors: | Malito, E, Mattevi, A. | Deposit date: | 2004-06-23 | Release date: | 2004-08-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of Michaelis and Product Complexes of Plant Cytokinin Dehydrogenase: Implications for Flavoenzyme Catalysis J.Mol.Biol., 341, 2004
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3CFS
| Structural basis of the interaction of RbAp46/RbAp48 with histone H4 | Descriptor: | ARSENIC, Histone H4, Histone-binding protein RBBP7 | Authors: | Murzina, N.V, Pei, X.-Y, Pratap, J.V, Sparkes, M, Vicente-Garcia, J, Ben-Shahar, T.R, Verreault, A, Luisi, B.F, Laue, E.D. | Deposit date: | 2008-03-04 | Release date: | 2008-06-10 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis for the Recognition of Histone H4 by the Histone-Chaperone RbAp46. Structure, 16, 2008
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1BC0
| RECOMBINANT RAT ANNEXIN V, W185A MUTANT | Descriptor: | ANNEXIN V, CALCIUM ION, SULFATE ION | Authors: | Mo, Y.D, Swairjo, M.A, Li, C.W, Head, J.F, Seaton, B.A. | Deposit date: | 1998-05-04 | Release date: | 1998-11-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components. Biochemistry, 37, 1998
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1JZU
| Cell transformation by the myc oncogene activates expression of a lipocalin: analysis of the gene (Q83) and solution structure of its protein product | Descriptor: | lipocalin Q83 | Authors: | Hartl, M, Matt, T, Schueler, W, Siemeister, G, Kontaxis, G, Kloiber, K, Konrat, R, Bister, K. | Deposit date: | 2001-09-17 | Release date: | 2003-07-15 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Cell Transformation by the v-myc Oncogene Abrogates c-Myc/Max-mediated Suppression of a
C/EBPbeta-dependent Lipocalin Gene. J.Mol.Biol., 333, 2003
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3W79
| Crystal Structure of azoreductase AzrC in complex with sulfone-modified azo dye Orange I | Descriptor: | 4-[(E)-(4-hydroxynaphthalen-1-yl)diazenyl]benzenesulfonic acid, FLAVIN MONONUCLEOTIDE, FMN-dependent NADH-azoreductase | Authors: | Ogata, D, Yu, J, Ooi, T, Yao, M. | Deposit date: | 2013-02-27 | Release date: | 2014-02-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of AzrA and of AzrC complexed with substrate or inhibitor: insight into substrate specificity and catalytic mechanism. Acta Crystallogr.,Sect.D, 70, 2014
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5VRI
| Crystal structure of SsoPox AsA6 mutant (F46L-C258A-W263M-I280T) - closed form | Descriptor: | 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ... | Authors: | Hiblot, J, Gotthard, G, Jacquet, P, Daude, D, Bergonzi, C, Chabriere, E, Elias, M. | Deposit date: | 2017-05-10 | Release date: | 2017-12-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase. Sci Rep, 7, 2017
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1JMA
| CRYSTAL STRUCTURE OF THE HERPES SIMPLEX VIRUS GLYCOPROTEIN D BOUND TO THE CELLULAR RECEPTOR HVEA/HVEM | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCOPROTEIN D, HERPESVIRUS ENTRY MEDIATOR, ... | Authors: | Carfi, A, Willis, S.H, Whitbeck, J.C, Krummenacker, C, Cohen, G.H, Eisenberg, R.J, Wiley, D.C. | Deposit date: | 2001-07-17 | Release date: | 2001-09-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Herpes simplex virus glycoprotein D bound to the human receptor HveA. Mol.Cell, 8, 2001
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1VKA
| Southeast Collaboratory for Structural Genomics: Hypothetical Human Protein Q15691 N-Terminal Fragment | Descriptor: | Microtubule-associated protein RP/EB family member 1 | Authors: | Liu, Z.-J, Tempel, W, Schubot, F.D, Shah, A, Dailey, T.A, Mayer, M.R, Rose, J.P, Dailey, H.A, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2004-05-10 | Release date: | 2004-07-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Southeast Collaboratory for Structural Genomics: Hypothetical Human Protein Q15691 N-Terminal Fragment TO BE PUBLISHED
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3SJU
| Hedamycin Polyketide Ketoreductase bound to NADPH | Descriptor: | Keto reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Javidpour, P, Tsai, S.-C. | Deposit date: | 2011-06-21 | Release date: | 2011-09-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural and Biochemical Studies of the Hedamycin Type II Polyketide Ketoreductase (HedKR): Molecular Basis of Stereo- and Regiospecificities. Biochemistry, 50, 2011
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1AV3
| POTASSIUM CHANNEL BLOCKER KAPPA CONOTOXIN PVIIA FROM C. PURPURASCENS, NMR, 20 STRUCTURES | Descriptor: | Kappa-conotoxin PVIIA | Authors: | Scanlon, M.J, Naranjo, D, Thomas, L, Alewood, P.F, Lewis, R.J, Craik, D.J. | Deposit date: | 1997-09-24 | Release date: | 1998-10-14 | Last modified: | 2020-12-16 | Method: | SOLUTION NMR | Cite: | Solution structure and proposed binding mechanism of a novel potassium channel toxin kappa-conotoxin PVIIA. Structure, 5, 1997
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5W48
| Crystal Structure of Riboflavin Lyase (RcaE) | Descriptor: | Riboflavin Lyase, SULFATE ION | Authors: | Bhandari, D.M, Chakrabarty, Y, Zhao, B, Wood, J, Li, P, Begley, T.P. | Deposit date: | 2017-06-09 | Release date: | 2018-06-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Cannibalism Among the Flavins: a Novel C-N Bond Cleavage in Riboflavin Catabolism Mediated by Flavin-Generated Superoxide Radical To be Published
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5W4X
| Truncated hUGDH | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, UDP-glucose 6-dehydrogenase | Authors: | Sennett, N.C, Custer, G.S, Wood, Z.A. | Deposit date: | 2017-06-13 | Release date: | 2017-07-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | The entropic force generated by intrinsically disordered segments tunes protein function. Nature, 563, 2018
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5W4Z
| Crystal Structure of Riboflavin Lyase (RcaE) with modified FMN and substrate Riboflavin | Descriptor: | 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-3-O-phosphono-D-ribitol, RIBOFLAVIN, Riboflavin Lyase | Authors: | Bhandari, D.M, Chakrabarty, Y, Zhao, B, Wood, J, Li, P, Begley, T.P. | Deposit date: | 2017-06-13 | Release date: | 2018-06-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Cannibalism Among the Flavins: a Novel C-N Bond Cleavage in Riboflavin Catabolism Mediated by Flavin-Generated Superoxide Radical To be Published
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3U86
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5W6B
| Phosphotriesterase variant S1 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase, ... | Authors: | Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. | Deposit date: | 2017-06-16 | Release date: | 2018-12-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.739 Å) | Cite: | Phosphotriesterase variant S1 To Be Published
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1DX6
| STRUCTURE OF ACETYLCHOLINESTERASE COMPLEXED WITH (-)-GALANTHAMINE AT 2.3A RESOLUTION | Descriptor: | (-)-GALANTHAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Greenblatt, H.M, Kryger, G, Lewis, T.T, Silman, I, Sussman, J.L. | Deposit date: | 1999-12-21 | Release date: | 2000-01-02 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of Acetylcholinesterase Complexed with (-)-Galanthamine at 2.3A Resolution FEBS Lett., 463, 1999
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