5VR8

Human UDP-Glucose Dehydrogenase with UDP-Xylose Bound to the Co-enzyme Site

Summary for 5VR8

• Entry DOI: 10.2210/pdb5vr8/pdb
• Descriptor: UDP-glucose 6-dehydrogenase, URIDINE-5'-DIPHOSPHATE-XYLOPYRANOSE, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: hugdh, udp-xylose, udx, udp-glucose dehydrogenase, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 6
• Total formula weight: 337609.68

Authors

Kadirvelraj, R.,Beattie, N.R.,Wood, Z.A. (deposition date: 2017-05-10, release date: 2017-07-19, Last modification date: 2023-04-26)

• Primary citation: Keul, N.D.,Oruganty, K.,Schaper Bergman, E.T.,Beattie, N.R.,McDonald, W.E.,Kadirvelraj, R.,Gross, M.L.,Phillips, R.S.,Harvey, S.C.,Wood, Z.A.; The entropic force generated by intrinsically disordered segments tunes protein function.; Nature, 563:584-588, 2018; PubMed: 30420606; DOI: 10.1038/s41586-018-0699-5

Experimental method

X-RAY DIFFRACTION (1.999 Å)