1R42
 
 | | Native Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ZINC ION, ... | | Authors: | Towler, P, Staker, B, Prasad, S.G, Menon, S, Ryan, D, Tang, J, Parsons, T, Fisher, M, Williams, D, Dales, N.A, Patane, M.A, Pantoliano, M.W. | | Deposit date: | 2003-10-07 | | Release date: | 2004-02-03 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis.
J.Biol.Chem., 279, 2004
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1R43
 | | Crystal structure of beta-alanine synthase from Saccharomyces kluyveri (selenomethionine substituted protein) | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-AMINO ISOBUTYRATE, ... | | Authors: | Lundgren, S, Gojkovic, Z, Piskur, J, Dobritzsch, D. | | Deposit date: | 2003-10-03 | | Release date: | 2003-11-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Yeast beta-Alanine Synthase Shares a Structural Scaffold and Origin with Dizinc-dependent Exopeptidases
J.Biol.Chem., 278
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1R44
 | | Crystal Structure of VanX | | Descriptor: | D-alanyl-D-alanine dipeptidase, ZINC ION | | Authors: | Pratt, S.D, Katz, L, Severin, J.M, Holzman, T, Park, C.H. | | Deposit date: | 2003-10-03 | | Release date: | 2004-06-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | The Structure of VanX Reveals a Novel Amino-Dipeptidase Involved in Mediating Transposon-Based Vancomycin Resistance
Mol.Cell, 2, 1998
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1R45
 | | ADP-ribosyltransferase C3bot2 from Clostridium botulinum, triclinic form | | Descriptor: | GLYCEROL, Mono-ADP-ribosyltransferase C3, SULFATE ION | | Authors: | Teplyakov, A, Obmolova, G, Gilliland, G.L, Narumiya, S. | | Deposit date: | 2003-10-03 | | Release date: | 2004-11-16 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | Crystal structure of ADP-ribosyltransferase C3bot2 from Clostridium botulinum
To be Published
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1R46
 | | Structure of human alpha-galactosidase | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Garman, S.C, Garboczi, D.N. | | Deposit date: | 2003-10-03 | | Release date: | 2004-03-16 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | The molecular defect leading to Fabry disease: structure of human alpha-galactosidase
J.Mol.Biol., 337, 2004
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1R47
 | | Structure of human alpha-galactosidase | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... | | Authors: | Garman, S.C, Garboczi, D.N. | | Deposit date: | 2003-10-03 | | Release date: | 2004-03-16 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.45 Å) | | Cite: | The molecular defect leading to Fabry disease: structure of human alpha-galactosidase
J.Mol.Biol., 337, 2004
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1R48
 | | Solution structure of the C-terminal cytoplasmic domain residues 468-497 of Escherichia coli protein ProP | | Descriptor: | Proline/betaine transporter | | Authors: | Zoetewey, D.L, Tripet, B.P, Kutateladze, T.G, Overduin, M.J, Wood, J.M, Hodges, R.S. | | Deposit date: | 2003-10-03 | | Release date: | 2003-12-23 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the C-terminal Antiparallel Coiled-coil Domain from Escherichia coli Osmosensor ProP.
J.Mol.Biol., 334, 2003
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1R49
 | | Human topoisomerase I (Topo70) double mutant K532R/Y723F | | Descriptor: | 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(P*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3', DNA topoisomerase I | | Authors: | Interthal, H, Quigley, P.M, Hol, W.G, Champoux, J.J. | | Deposit date: | 2003-10-03 | | Release date: | 2003-12-16 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.13 Å) | | Cite: | The role of lysine 532 in the catalytic mechanism of human topoisomerase I.
J.Biol.Chem., 279, 2004
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1R4A
 | | Crystal Structure of GTP-bound ADP-ribosylation Factor Like Protein 1 (Arl1) and GRIP Domain of Golgin245 COMPLEX | | Descriptor: | ADP-ribosylation factor-like protein 1, Golgi autoantigen, golgin subfamily A member 4, ... | | Authors: | Wu, M, Lu, L, Hong, W, Song, H. | | Deposit date: | 2003-10-04 | | Release date: | 2004-01-13 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for recruitment of GRIP domain golgin-245 by small GTPase Arl1.
Nat.Struct.Mol.Biol., 11, 2004
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1R4B
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1R4C
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1R4D
 | | Solution structure of the chimeric L/D DNA oligonucleotide d(C8metGCGC(L)G(L)CGCG)2 | | Descriptor: | 5'-D(*CP*(8MG)P*CP*GP*(0DC)P*(0DG)P*CP*GP*CP*G)-3' | | Authors: | Cherrak, I, Mauffret, O, Santamaria, F, Rayner, B, Hocquet, A, Ghomi, M, Fermandjian, S. | | Deposit date: | 2003-10-06 | | Release date: | 2003-10-21 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | L-nucleotides and 8-methylguanine of d(C1m8G2C3G4C5LG6LC7G8C9G10)2 act cooperatively to promote a left-handed helix under physiological salt conditions.
Nucleic Acids Res., 31, 2003
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1R4E
 | | Solution structure of the Complex Formed between a Left-Handed Wedge-Shaped Spirocyclic Molecule and Bulged DNA | | Descriptor: | 5'-D(*CP*AP*CP*GP*CP*AP*GP*TP*TP*CP*GP*GP*AP*C)-3', 5'-D(*GP*TP*CP*CP*GP*AP*TP*GP*CP*GP*TP*G)-3', SPIRO[NAPHTHALENE-2(3H),3'(10'H)-PENTALENO[1,2-B]NAPHTHALENE]-3,10'-DIONE, ... | | Authors: | Hwang, G.S, Jones, G.B, Goldberg, I.H. | | Deposit date: | 2003-10-06 | | Release date: | 2004-04-27 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Stereochemical control of small molecule binding to bulged DNA: comparison of structures of spirocyclic enantiomer-bulged DNA complexes.
Biochemistry, 43, 2004
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1R4F
 | | Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma vivax: Trp260Ala Mutant In Complex With 3-Deaza-Adenosine | | Descriptor: | 3-DEAZA-ADENOSINE, CALCIUM ION, IAG-nucleoside hydrolase | | Authors: | Versees, W, Loverix, S, Vandemeulebroucke, A, Geerlings, P, Steyaert, J. | | Deposit date: | 2003-10-06 | | Release date: | 2004-04-13 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Leaving group activation by aromatic stacking: an alternative to general Acid catalysis.
J.Mol.Biol., 338, 2004
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1R4G
 | | Solution structure of the Sendai virus protein X C-subdomain | | Descriptor: | RNA polymerase alpha subunit | | Authors: | Blanchard, L, Tarbouriech, N, Blackledge, M, Timmins, P, Burmeister, W.P, Ruigrok, R.W, Marion, D. | | Deposit date: | 2003-10-06 | | Release date: | 2004-03-09 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure and dynamics of the nucleocapsid-binding domain of the Sendai virus phosphoprotein in solution
Virology, 319, 2004
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1R4H
 | | NMR Solution structure of the IIIc domain of GB Virus B IRES Element | | Descriptor: | 5'-R(*GP*GP*GP*CP*AP*AP*GP*CP*CP*C)-3' | | Authors: | Kaluarachchi, K, Thiviyanathan, V, Rijinbrand, R, Lemon, S.M, Gorenstein, D.G. | | Deposit date: | 2003-10-06 | | Release date: | 2004-10-19 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Mutational and structural analysis of stem-loop IIIC of the hepatitis C virus and GB virus B internal ribosome entry sites.
J.Mol.Biol., 343, 2004
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1R4I
 | | Crystal Structure of Androgen Receptor DNA-Binding Domain Bound to a Direct Repeat Response Element | | Descriptor: | 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*AP*AP*GP*AP*AP*CP*AP*G)-3', 5'-D(*CP*TP*GP*TP*TP*CP*TP*TP*GP*AP*TP*GP*TP*TP*CP*TP*GP*G)-3', Androgen receptor, ... | | Authors: | Shaffer, P.L, Jivan, A, Dollins, D.E, Claessens, F, Gewirth, D.T. | | Deposit date: | 2003-10-06 | | Release date: | 2004-06-29 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis of androgen receptor binding to selective androgen response elements.
Proc.Natl.Acad.Sci.USA, 101, 2004
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1R4K
 | | Solution Structure of the Drosophila Argonaute 1 PAZ Domain | | Descriptor: | Argonaute 1 | | Authors: | Yan, K.S, Yan, S, Farooq, A, Han, A, Zeng, L, Zhou, M.-M. | | Deposit date: | 2003-10-07 | | Release date: | 2003-12-09 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure and conserved RNA binding of the PAZ domain
Nature, 426, 2003
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1R4L
 | | Inhibitor Bound Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2) | | Descriptor: | (S,S)-2-{1-CARBOXY-2-[3-(3,5-DICHLORO-BENZYL)-3H-IMIDAZOL-4-YL]-ETHYLAMINO}-4-METHYL-PENTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | Authors: | Towler, P, Staker, B, Prasad, S.G, Menon, S, Ryan, D, Tang, J, Parsons, T, Fisher, M, Williams, D, Dales, N.A, Patane, M.A, Pantoliano, M.W. | | Deposit date: | 2003-10-07 | | Release date: | 2004-02-03 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis.
J.Biol.Chem., 279, 2004
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1R4M
 | | APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex | | Descriptor: | Ubiquitin-like protein NEDD8, ZINC ION, amyloid beta precursor protein-binding protein 1, ... | | Authors: | Walden, H, Podgorski, M.S, Holton, J.M, Schulman, B.A. | | Deposit date: | 2003-10-07 | | Release date: | 2003-12-23 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
Mol.Cell, 12, 2003
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1R4N
 | | APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Ubiquitin-like protein NEDD8, ZINC ION, ... | | Authors: | Walden, H, Podgorski, M.S, Holton, J.M, Schulman, B.A. | | Deposit date: | 2003-10-07 | | Release date: | 2003-12-23 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
Mol.Cell, 12, 2003
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1R4O
 | | Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA | | Descriptor: | 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*GP*AP*TP*GP*TP*TP*CP*TP*G)-3', Glucocorticoid receptor, ZINC ION | | Authors: | Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B. | | Deposit date: | 2003-10-07 | | Release date: | 2003-10-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystallographic Analysis of the Interaction of The Glucocorticoid Receptor with DNA
Nature, 352, 1991
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1R4P
 | | Shiga toxin type 2 | | Descriptor: | 1,2-ETHANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, FORMIC ACID, ... | | Authors: | Fraser, M.E, Fujinaga, M, Cherney, M.M, Melton-Celsa, A.R, Twiddy, E.M, O'Brien, A.D, James, M.N.G. | | Deposit date: | 2003-10-07 | | Release date: | 2004-05-11 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Structure of Shiga Toxin Type 2 (Stx2) from Escherichia coli O157:H7.
J.Biol.Chem., 279, 2004
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1R4Q
 | | Shiga toxin | | Descriptor: | SHT cytotoxin A subunit, Shigella toxin chain B | | Authors: | Fraser, M.E, Fujinaga, M, Cherney, M.M, Melton-Celsa, A.R, Twiddy, E.M, O'Brien, A.D, James, M.N.G. | | Deposit date: | 2003-10-07 | | Release date: | 2004-05-11 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of Shiga Toxin Type 2 (Stx2) from Escherichia coli O157:H7.
J.Biol.Chem., 279, 2004
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1R4R
 | | Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA | | Descriptor: | 5'-D(*CP*TP*GP*AP*GP*AP*AP*CP*AP*TP*CP*AP*TP*GP*TP*TP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*TP*GP*AP*TP*GP*TP*TP*CP*TP*CP*A)-3', Glucocorticoid receptor, ... | | Authors: | Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B. | | Deposit date: | 2003-10-07 | | Release date: | 2003-10-28 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystallographic Analysis of the Interaction of the Glucocorticoid Receptor with DNA
Nature, 352, 1991
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