5JOJ
| Calcium-loaded EF-hand domain of L-plastin | Descriptor: | CALCIUM ION, Plastin-2 | Authors: | Ishida, H, Jensen, K.V, Woodman, G.W, Hyndman, M.E, Vogel, H.J. | Deposit date: | 2016-05-02 | Release date: | 2017-04-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The Calcium-Dependent Switch Helix of L-Plastin Regulates Actin Bundling. Sci Rep, 7, 2017
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5G4P
| Crystal structure of human hippocalcin at 2.4 A resolution | Descriptor: | CALCIUM ION, Neuron-specific calcium-binding protein hippocalcin | Authors: | Antonyuk, S.V, Helassa, N, Lian, L.Y, Haynes, L.P, Burgoyne, R.D. | Deposit date: | 2016-05-15 | Release date: | 2017-05-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Biophysical and functional characterization of hippocalcin mutants responsible for human dystonia. Hum. Mol. Genet., 26, 2017
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5G58
| Crystal structure of A190T mutant of human hippocalcin AT 2.5 A resolution | Descriptor: | CALCIUM ION, Neuron-specific calcium-binding protein hippocalcin | Authors: | Antonyuk, S.V, Helassa, N, Lian, L.Y, Haynes, L.P, Burgoyne, R.D. | Deposit date: | 2016-05-22 | Release date: | 2017-05-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Biophysical and functional characterization of hippocalcin mutants responsible for human dystonia. Hum. Mol. Genet., 26, 2017
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5K89
| Crystal Structure of Human Calcium-Bound S100A1 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Protein S100-A1 | Authors: | Melville, Z, Aligholizadeh, E, McKnight, L.E, Weber, D, Pozharski, E, Weber, D.J. | Deposit date: | 2016-05-27 | Release date: | 2017-04-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.249 Å) | Cite: | X-ray crystal structure of human calcium-bound S100A1. Acta Crystallogr F Struct Biol Commun, 73, 2017
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5M6C
| CRYSTAL STRUCTURE OF T71N MUTANT OF HUMAN HIPPOCALCIN | Descriptor: | CALCIUM ION, Neuron-specific calcium-binding protein hippocalcin | Authors: | Helassa, N, Antonyuk, S.V, Lian, L.Y, Haynes, L.P, Burgoyne, R.D. | Deposit date: | 2016-10-24 | Release date: | 2017-04-12 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Biophysical and functional characterization of hippocalcin mutants responsible for human dystonia. Hum. Mol. Genet., 26, 2017
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6EPA
| Structure of dNCS-1 bound to the NCS-1/Ric8a protein/protein interaction regulator IGS-1.76 | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, CALCIUM ION, FI18190p1, ... | Authors: | Sanchez-Barrena, M.J, Daniel, M, Infantes, L. | Deposit date: | 2017-10-11 | Release date: | 2018-08-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators. J. Med. Chem., 61, 2018
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6FIE
| Crystallographic structure of calcium loaded Calbindin-D28K. | Descriptor: | CALCIUM ION, Calbindin, THIOCYANATE ION | Authors: | Noble, J.W, Almalki, R, Roe, S.M, Wagner, A, Dumanc, R, Atack, J.R. | Deposit date: | 2018-01-18 | Release date: | 2018-10-10 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | The X-ray structure of human calbindin-D28K: an improved model. Acta Crystallogr D Struct Biol, 74, 2018
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6QI4
| NCS-1 bound to a ligand | Descriptor: | 2-(1~{H}-indol-3-yl)-~{N}-[(~{E})-(4-nitro-3-oxidanyl-phenyl)methylideneamino]ethanamide, ACETATE ION, CALCIUM ION, ... | Authors: | Sanchez-Barrena, M.J, Blanco-Gabella, P. | Deposit date: | 2019-01-17 | Release date: | 2019-07-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Insights into real-time chemical processes in a calcium sensor protein-directed dynamic library. Nat Commun, 10, 2019
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6LKZ
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6XU4
| Crystal structure of the genetically-encoded FGCaMP calcium indicator in its calcium-bound state | Descriptor: | CALCIUM ION, FGCamp | Authors: | Boyko, K.M, Nikolaeva, A.Y, Korzhenevskiy, D.A, Barykina, N.V, Subach, O.M, Subach, F.V. | Deposit date: | 2020-01-17 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.18 Å) | Cite: | FGCaMP7, an Improved Version of Fungi-Based Ratiometric Calcium Indicator for In Vivo Visualization of Neuronal Activity. Int J Mol Sci, 21, 2020
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6WXR
| CryoEM structure of mouse DUOX1-DUOXA1 complex in the absence of NADPH | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Dual oxidase 1, Dual oxidase maturation factor 1, ... | Authors: | Sun, J. | Deposit date: | 2020-05-11 | Release date: | 2020-09-02 | Last modified: | 2021-03-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation. Nat.Struct.Mol.Biol., 27, 2020
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6WXU
| CryoEM structure of mouse DUOX1-DUOXA1 complex in the dimer-of-dimer state | Descriptor: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | Authors: | Sun, J. | Deposit date: | 2020-05-12 | Release date: | 2020-09-02 | Last modified: | 2021-03-17 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation. Nat.Struct.Mol.Biol., 27, 2020
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6WXV
| CryoEM structure of mouse DUOX1-DUOXA1 complex in the presence of NADPH | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | Authors: | Sun, J. | Deposit date: | 2020-05-12 | Release date: | 2020-09-02 | Last modified: | 2021-03-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation. Nat.Struct.Mol.Biol., 27, 2020
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7K5B
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7D3E
| Cryo-EM structure of human DUOX1-DUOXA1 in low-calcium state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Dual oxidase 1, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Chen, L, Wu, J.X. | Deposit date: | 2020-09-19 | Release date: | 2020-12-09 | Last modified: | 2021-06-23 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structures of human dual oxidase 1 complex in low-calcium and high-calcium states. Nat Commun, 12, 2021
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7D3F
| Cryo-EM structure of human DUOX1-DUOXA1 in high-calcium state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Dual oxidase 1, ... | Authors: | Chen, L, Wu, J.X. | Deposit date: | 2020-09-19 | Release date: | 2020-12-09 | Last modified: | 2021-06-23 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structures of human dual oxidase 1 complex in low-calcium and high-calcium states. Nat Commun, 12, 2021
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7DSV
| Structure of a human NHE1-CHP1 complex under pH 6.5 | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Calcineurin B homologous protein 1, Sodium/hydrogen exchanger 1 | Authors: | Dong, Y, Gao, Y, Li, B, Zhang, X.C, Zhao, Y. | Deposit date: | 2021-01-03 | Release date: | 2021-06-23 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure and mechanism of the human NHE1-CHP1 complex. Nat Commun, 12, 2021
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7DSX
| Structure of a human NHE1-CHP1 complex under pH 7.5, bound by cariporide | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Calcineurin B homologous protein 1, N-[bis(azanyl)methylidene]-3-methylsulfonyl-4-propan-2-yl-benzamide, ... | Authors: | Dong, Y, Gao, Y, Li, B, Zhang, X.C, Zhao, Y. | Deposit date: | 2021-01-03 | Release date: | 2021-06-23 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure and mechanism of the human NHE1-CHP1 complex. Nat Commun, 12, 2021
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7X2U
| Structure of a human NHE3-CHP1 complex in the autoinhibited state | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Calcineurin B homologous protein 1, Sodium/hydrogen exchanger 3, ... | Authors: | Dong, Y, Li, H, Gao, Y, Zhang, X.C, Zhao, Y. | Deposit date: | 2022-02-26 | Release date: | 2022-04-20 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of a human NHE3-CHP1 complex in the autoinhibited state Sci Adv, 2022
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8AHY
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8ALM
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8ALH
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8BAV
| Secretagogin (human) in complex with its target peptide from SNAP-25 | Descriptor: | ACETATE ION, CALCIUM ION, Green fluorescent protein,Synaptosomal-associated protein 25, ... | Authors: | Schnell, R, Szodorai, E. | Deposit date: | 2022-10-12 | Release date: | 2024-04-03 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A hydrophobic groove in secretagogin allows for alternate interactions with SNAP-25 and syntaxin-4 in endocrine tissues. Proc.Natl.Acad.Sci.USA, 121, 2024
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8BX8
| In situ outer dynein arm from Chlamydomonas reinhardtii in the post-power stroke state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ... | Authors: | Zimmermann, N.E.L, Noga, A, Obbineni, J.M, Ishikawa, T. | Deposit date: | 2022-12-08 | Release date: | 2023-05-10 | Last modified: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (30.299999 Å) | Cite: | ATP-induced conformational change of axonemal outer dynein arms revealed by cryo-electron tomography. Embo J., 42, 2023
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8FJ8
| Crystal structure of Mn(2+),Ca(2+)-S100B | Descriptor: | CALCIUM ION, MANGANESE (II) ION, Protein S100-B | Authors: | Hunter, D.A. | Deposit date: | 2022-12-19 | Release date: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Structural insights into ions binding to S100A1 versus S100B To Be Published
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