7DSX

Structure of a human NHE1-CHP1 complex under pH 7.5, bound by cariporide

Summary for 7DSX

• Entry DOI: 10.2210/pdb7dsx/pdb
• EMDB information: 30849
• Descriptor: Calcineurin B homologous protein 1, Sodium/hydrogen exchanger 1, (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ... (4 entities in total)
• Functional Keywords: transporter, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 162013.22

Authors

Dong, Y.,Gao, Y.,Li, B.,Zhang, X.C.,Zhao, Y. (deposition date: 2021-01-03, release date: 2021-06-23, Last modification date: 2024-03-27)

• Primary citation: Dong, Y.,Gao, Y.,Ilie, A.,Kim, D.,Boucher, A.,Li, B.,Zhang, X.C.,Orlowski, J.,Zhao, Y.; Structure and mechanism of the human NHE1-CHP1 complex.; Nat Commun, 12:3474-3474, 2021; PubMed: 34108458; DOI: 10.1038/s41467-021-23496-z

Experimental method

ELECTRON MICROSCOPY (3.5 Å)