7D3F

Cryo-EM structure of human DUOX1-DUOXA1 in high-calcium state

Summary for 7D3F

• Entry DOI: 10.2210/pdb7d3f/pdb
• EMDB information: 30556
• Descriptor: Dual oxidase 1, Isoform 2 of Dual oxidase maturation factor 1, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• Functional Keywords: duox, duoxa, nox, nadph, fad, haem, electron transport
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 473561.33

Authors

Chen, L.,Wu, J.X. (deposition date: 2020-09-19, release date: 2020-12-09, Last modification date: 2021-06-23)

• Primary citation: Wu, J.X.,Liu, R.,Song, K.,Chen, L.; Structures of human dual oxidase 1 complex in low-calcium and high-calcium states.; Nat Commun, 12:155-155, 2021; PubMed: 33420071; DOI: 10.1038/s41467-020-20466-9

Experimental method

ELECTRON MICROSCOPY (2.3 Å)