PDB: 72372 resultsInfo pagesStatus searchChemie searchBIRD

---

7QQX	SpCas9 bound to FANCF off-target5 DNA substrate Descriptor: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target5 non-target strand, FANCF off-target5 target strand, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-01-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QQT	SpCas9 bound to FANCF off-target1 DNA substrate Descriptor: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target1 non-target strand, FANCF off-target1 target strand, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-01-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QR0	SpCas9 bound to TRAC off-target1 DNA substrate Descriptor: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-01-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QR8	SpCas9 bound to PTPRC off-target1 DNA substrate Descriptor: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-01-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QQZ	SpCas9 bound to FANCF off-target7 DNA substrate Descriptor: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target7 non-target strand, FANCF off-target7 target strand, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-01-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QQW	SpCas9 bound to FANCF off-target4 DNA substrate Descriptor: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target4 non-target strand, FANCF off-target4 target strand, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-01-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QR1	SpCas9 bound to TRAC off-target2 DNA substrate Descriptor: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-01-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QR7	SpCas9 bound to AAVS1 off-target2 DNA substrate Descriptor: AAVS1 off-target2 non-target strand, AAVS1 off-target2 target strand, AAVS1 sgRNA, ... Authors: Pacesa, M, JInek, M. Deposit date: 2022-01-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis for Cas9 off-target activity. Cell, 185, 2022
5D9J	2009 H1N1 PA endonuclease mutant F105S in complex with L-742,001 Descriptor: (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, MANGANESE (II) ION, Polymerase acidic protein Authors: Kumar, G, White, S.W. Deposit date: 2015-08-18 Release date: 2016-03-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc.Natl.Acad.Sci.USA, 113, 2016
5D2O	2009 H1N1 PA endonuclease mutant F105S Descriptor: MANGANESE (II) ION, Polymerase acidic protein Authors: Kumar, G, White, S.W. Deposit date: 2015-08-05 Release date: 2016-03-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc.Natl.Acad.Sci.USA, 113, 2016
5NZZ	Crystal structure of phosphorylated p38aMAPK in complex with TAB1 Descriptor: MAGNESIUM ION, Mitogen-activated protein kinase 14, NICKEL (II) ION, ... Authors: Nichols, C.E, De Nicola, G.F. Deposit date: 2017-05-15 Release date: 2018-05-30 Last modified: 2018-09-19 Method: X-RAY DIFFRACTION (2.6 Å) Cite: The TAB1-p38 alpha complex aggravates myocardial injury and can be targeted by small molecules. JCI Insight, 3, 2018
5DBS	2009 H1N1 PA endonuclease mutant E119D in complex with dTMP Descriptor: MANGANESE (II) ION, Polymerase acidic protein, SULFATE ION, ... Authors: Kumar, G, White, S.W. Deposit date: 2015-08-21 Release date: 2016-03-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5CZN	2009 H1N1 PA endonuclease mutant E119D Descriptor: MANGANESE (II) ION, Polymerase acidic protein, SULFATE ION Authors: Kumar, G, White, S.W. Deposit date: 2015-07-31 Release date: 2016-03-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc.Natl.Acad.Sci.USA, 113, 2016
2B57	Guanine Riboswitch C74U mutant bound to 2,6-diaminopurine Descriptor: 65-MER, 9H-PURINE-2,6-DIAMINE, ACETATE ION, ... Authors: Gilbert, S.D, Stoddard, C.D, Wise, S.J, Batey, R.T. Deposit date: 2005-09-27 Release date: 2006-05-23 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain. J.Mol.Biol., 359, 2006
5DES	2009 H1N1 PA endonuclease domain Descriptor: MANGANESE (II) ION, Polymerase acidic protein Authors: Kumar, G, White, S.W. Deposit date: 2015-08-25 Release date: 2016-03-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc.Natl.Acad.Sci.USA, 113, 2016
8OPF	Virus-like Particle based on PVY coat protein with dC60 deletion with RNA-free helical architecture Descriptor: Genome polyprotein (Fragment) Authors: Kavcic, L, Kezar, A, Podobnik, M. Deposit date: 2023-04-07 Release date: 2024-01-24 Last modified: 2024-01-31 Method: ELECTRON MICROSCOPY (2.83 Å) Cite: From structural polymorphism to structural metamorphosis of the coat protein of flexuous filamentous potato virus Y. Commun Chem, 7, 2024
6KDM	HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:entecavir 5'-triphosphate ternary complex Descriptor: DNA/RNA (38-MER), GLYCEROL, HIV-1 RT p51 subunit, ... Authors: Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. Deposit date: 2019-07-02 Release date: 2020-03-04 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020
6KDN	HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:dGTP ternary complex Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... Authors: Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. Deposit date: 2019-07-02 Release date: 2020-03-04 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.303 Å) Cite: Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020
6KDJ	HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:lamivudine 5'-triphosphate ternary complex Descriptor: DNA/RNA (38-MER), GLYCEROL, HIV-1 RT p51 subunit, ... Authors: Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. Deposit date: 2019-07-02 Release date: 2020-03-04 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020
6KDK	HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:dCTP ternary complex Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... Authors: Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. Deposit date: 2019-07-02 Release date: 2020-03-04 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.56 Å) Cite: Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020
6KDO	HIV-1 reverse transcriptase with Q151M/Y115F/F116Y/M184V/F160M:DNA:lamivudine 5'-triphosphate ternary complex Descriptor: DNA/RNA (38-MER), GLYCEROL, HIV-1 RT p51 subunit, ... Authors: Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. Deposit date: 2019-07-02 Release date: 2020-03-04 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.573 Å) Cite: Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020
1QGV	HUMAN SPLICEOSOMAL PROTEIN U5-15KD Descriptor: SPLICEOSOMAL PROTEIN U5-15KD Authors: Reuter, K, Nottrott, S, Fabrizio, P, Luehrmann, R, Ficner, R. Deposit date: 1999-05-06 Release date: 1999-12-12 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Identification, characterization and crystal structure analysis of the human spliceosomal U5 snRNP-specific 15 kD protein. J.Mol.Biol., 294, 1999
6LBB	Crystal structure of barley exohydrolaseI W434A mutant in complex with 4I,4III,4V-S-trithiocellohexaose Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Beta-D-glucan exohydrolase isoenzyme ExoI, ... Authors: Luang, S, Streltsov, V.A, Hrmova, M. Deposit date: 2019-11-14 Release date: 2020-09-30 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases. Nat Commun, 13, 2022
6LBV	Crystal structure of barley exohydrolaseI W434F mutant in complex with methyl 6-thio-beta-gentiobioside Descriptor: ACETATE ION, Beta-D-glucan exohydrolase isoenzyme ExoI, GLYCEROL, ... Authors: Luang, S, Streltsov, V.A, Hrmova, M. Deposit date: 2019-11-15 Release date: 2020-09-30 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.89 Å) Cite: The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases. Nat Commun, 13, 2022
1EQP	EXO-B-(1,3)-GLUCANASE FROM CANDIDA ALBICANS Descriptor: EXO-B-(1,3)-GLUCANASE Authors: Cutfield, J.F, Sullivan, P.A, Cutfield, S.M. Deposit date: 2000-04-05 Release date: 2001-02-28 Last modified: 2017-10-04 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Minor structural consequences of alternative CUG codon usage (Ser for Leu) in Candida albicans exoglucanase. Protein Eng., 13, 2000

<771772773774775776777778779780781782783784785786>