5DBS

2009 H1N1 PA endonuclease mutant E119D in complex with dTMP

Summary for 5DBS

Entry DOI	10.2210/pdb5dbs/pdb
Related	5CCY 5CGV 5CL0 5CZN 5D2O 5D42 5D4G 5D8U 5D9J
Descriptor	Polymerase acidic protein, MANGANESE (II) ION, SULFATE ION, ... (5 entities in total)
Functional Keywords	influenza, resistance, endonuclease inhibitor, hydrolase, viral protein
Biological source	Influenza A virus
Total number of polymer chains	1
Total formula weight	23607.52
Authors	Kumar, G.,White, S.W. (deposition date: 2015-08-21, release date: 2016-03-23, Last modification date: 2023-09-27)
Primary citation	Song, M.S.,Kumar, G.,Shadrick, W.R.,Zhou, W.,Jeevan, T.,Li, Z.,Slavish, P.J.,Fabrizio, T.P.,Yoon, S.W.,Webb, T.R.,Webby, R.J.,White, S.W. Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc. Natl. Acad. Sci. U.S.A., 113:3669-3674, 2016 Cited by PubMed: 26976575 DOI: 10.1073/pnas.1519772113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.11 Å)

Structure validation