5CZN

2009 H1N1 PA endonuclease mutant E119D

Summary for 5CZN

Entry DOI	10.2210/pdb5czn/pdb
Related	5CCY 5CGV 5CL0 5D2O 5D42
Descriptor	Polymerase acidic protein, MANGANESE (II) ION, SULFATE ION, ... (4 entities in total)
Functional Keywords	influenza, resistance, endonuclease inhibitor, hydrolase, viral protein
Biological source	Influenza A virus More
Total number of polymer chains	1
Total formula weight	23381.38
Authors	Kumar, G.,White, S.W. (deposition date: 2015-07-31, release date: 2016-03-16, Last modification date: 2023-09-27)
Primary citation	Song, M.S.,Kumar, G.,Shadrick, W.R.,Zhou, W.,Jeevan, T.,Li, Z.,Slavish, P.J.,Fabrizio, T.P.,Yoon, S.W.,Webb, T.R.,Webby, R.J.,White, S.W. Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc.Natl.Acad.Sci.USA, 113:3669-3674, 2016 Cited by PubMed: 26976575 DOI: 10.1073/pnas.1519772113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.98 Å)

Structure validation