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7XI7	Human dihydrofolate reductase complexed with P39 Descriptor: 6-hexyl-5-phenyl-pyrimidine-2,4-diamine, Dihydrofolate reductase, SULFATE ION Authors: Vanichtanankul, J, Saeyang, T, Kamchonwongpaisan, S, Yuvaniyama, J, Yuthavong, Y. Deposit date: 2022-04-12 Release date: 2022-06-29 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structural Insight into Effective Inhibitors' Binding to Toxoplasma gondii Dihydrofolate Reductase Thymidylate Synthase. Acs Chem.Biol., 17, 2022
7XX6	Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment) Descriptor: CALCIUM ION, DNA (169-MER), Histone H1.0, ... Authors: Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A. Deposit date: 2022-05-28 Release date: 2023-05-31 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.39 Å) Cite: Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment) To Be Published
7XVL	Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169an DNA fragment) Descriptor: DNA (169-MER), Histone H1.0, Histone H2A type 1-B/E, ... Authors: Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A. Deposit date: 2022-05-24 Release date: 2023-05-24 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.506 Å) Cite: Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169an DNA fragment) To Be Published
8BPA	Cryo-EM structure of the human SIN3B histone deacetylase complex at 3.7 Angstrom Descriptor: CALCIUM ION, Histone deacetylase 2, Isoform 2 of Paired amphipathic helix protein Sin3b, ... Authors: Wan, M.S.M, Muhammad, R, Koliopolous, M.G, Alfieri, C. Deposit date: 2022-11-16 Release date: 2023-05-10 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex. Nat Commun, 14, 2023
7XUZ	Crystal structure of a HDAC4-MEF2A-DNA ternary complex Descriptor: DNA (5'-D(*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*T)-3'), DNA (5'-D(P*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*A)-3'), Histone deacetylase 4, ... Authors: Dai, S.Y, Guo, L, Dey, R, Guo, M, Bates, D, Cayford, J, Chen, X.J, Wei, X.D, Chen, L, Chen, Y.H. Deposit date: 2022-05-20 Release date: 2023-11-29 Last modified: 2024-06-12 Method: X-RAY DIFFRACTION (3.591 Å) Cite: Structural insights into the HDAC4-MEF2A-DNA complex and its implication in long-range transcriptional regulation. Nucleic Acids Res., 52, 2024
5X4Y	Mutant human thymidylate synthase M190K crystallized in a sulfate-containing condition Descriptor: SULFATE ION, Thymidylate synthase Authors: Chen, D, Jansson, A, Larsson, A, Nordlund, P. Deposit date: 2017-02-14 Release date: 2017-06-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states J. Biol. Chem., 292, 2017
5X5Q	Human thymidylate synthase complexed with dUMP and raltitrexed Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, TOMUDEX, Thymidylate synthase Authors: Chen, D, Jansson, A, Larsson, A, Nordlund, P. Deposit date: 2017-02-17 Release date: 2017-06-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.79 Å) Cite: Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states J. Biol. Chem., 292, 2017
7N40	Crystal structure of LIN9-RbAp48-LIN37, a MuvB subcomplex Descriptor: Histone-binding protein RBBP4, Isoform 2 of Protein lin-9 homolog, Protein lin-37 homolog Authors: Asthana, A, Ramanan, P, Tripathi, S.M, Rubin, S.M. Deposit date: 2021-06-02 Release date: 2022-02-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.55 Å) Cite: The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes. Nat Commun, 13, 2022
5X67	Human thymidylate synthase in complex with dUMP and nolatrexed Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-azanyl-6-methyl-5-pyridin-4-ylsulfanyl-3H-quinazolin-4-one, Thymidylate synthase Authors: Chen, D, Jansson, A, Larsson, A, Nordlund, P. Deposit date: 2017-02-21 Release date: 2017-06-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states. J. Biol. Chem., 292, 2017
5X4X	Mutant human thymidylate synthase A191K crystallized in a sulfate-containing condition Descriptor: SULFATE ION, Thymidylate synthase Authors: Chen, D, Jansson, A, Larsson, A, Nordlund, P. Deposit date: 2017-02-14 Release date: 2017-06-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states J. Biol. Chem., 292, 2017
5X69	Human thymidylate synthase with a fragment bound in the dimer interface Descriptor: 1-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-methanamine, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase Authors: Chen, D, Jansson, A, Larsson, A, Nordlund, P. Deposit date: 2017-02-21 Release date: 2017-06-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states J. Biol. Chem., 292, 2017
5X4W	Mutant human thymidylate synthase A191K crystallized in a sulfate-free condition Descriptor: PHOSPHATE ION, Thymidylate synthase Authors: Chen, D, Jansson, A, Larsson, A, Nordlund, P. Deposit date: 2017-02-14 Release date: 2017-06-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states J. Biol. Chem., 292, 2017
5X5D	Human thymidylate synthase bound with dUMP Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase Authors: Chen, D, Jansson, A, Larsson, A, Nordlund, P. Deposit date: 2017-02-15 Release date: 2017-06-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states J. Biol. Chem., 292, 2017
8EJV	The crystal structure of Pseudomonas putida PcaR in complex with succinate Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ... Authors: Pham, C, Skarina, T, Di Leo, R, Stogios, P.J, Mahadevan, R, Savchenko, A. Deposit date: 2022-09-19 Release date: 2024-03-20 Method: X-RAY DIFFRACTION (2.43 Å) Cite: The crystal structure of Pseudomonas putida PcaR in complex with succinate To Be Published
8EJU	The crystal structure of Pseudomonas putida PcaR Descriptor: CHLORIDE ION, PHOSPHATE ION, Transcription regulatory protein (Pca regulon), ... Authors: Pham, C, Skarina, T, Di Leo, R, Stogios, P.J, Mahadevan, R, Savchenko, A. Deposit date: 2022-09-19 Release date: 2024-03-20 Method: X-RAY DIFFRACTION (1.74 Å) Cite: The crystal structure of Pseudomonas putida PcaR To Be Published
8D7I	Bifunctional Inhibition of Neutrophil Elastase and Cathepsin G by Eap1 from S. aureus Descriptor: Cathepsin G, C-terminal truncated form, Extracellular Adherence Protein, ... Authors: Gido, C.D, Herdendorf, T.J, Geisbrecht, B.V. Deposit date: 2022-06-07 Release date: 2023-06-14 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.63 Å) Cite: Bifunctional Inhibition of Neutrophil Elastase and Cathepsin G by Eap1 from S. aureus To Be Published
8D7K	Bifunctional Inhibition of Neutrophil Elastase and Cathepsin G by Eap2 from S. aureus Descriptor: Cathepsin G, C-terminal truncated form, Extracellular Adherence Protein, ... Authors: Gido, C.D, Herdendorf, T.J, Geisbrecht, B.V. Deposit date: 2022-06-07 Release date: 2023-06-14 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Bifunctional Inhibition of Neutrophil Elastase and Cathepsin G by Eap2 from S. aureus To Be Published
2PSN	Crystal structure of enolase1 Descriptor: Alpha-enolase, MAGNESIUM ION, PHOSPHATE ION Authors: Hyo, J.K, Seung, J.K, Sang, J.C. Deposit date: 2007-05-07 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structure of Enolase1 alpha To be Published
3Q3S	EthR from Mycobacterium tuberculosis in complex with compound BDM5683 Descriptor: 2-(2-methylphenoxy)-N-[2-(4-methylphenyl)-2H-benzotriazol-5-yl]acetamide, HTH-type transcriptional regulator EthR Authors: Lens, Z, Willand, N, Villeret, V. Deposit date: 2010-12-22 Release date: 2012-01-18 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: EthR from Mycobacterium tuberculosis in complex with compound BDM5683 To be Published
5TN2	Solution Structure of the C-terminal multimerization domain of the master biofilm-regulator SinR from Bacillus subtilis Descriptor: HTH-type transcriptional regulator SinR Authors: Draughn, G.L, Bobay, B.G, Stowe, S.D, Thompson, R.J, Cavanagh, J. Deposit date: 2016-10-13 Release date: 2017-10-25 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis. J.Mol.Biol., 2019
6BY1	E. coli pH03H9 complex Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Amiri, H, Noller, H.F. Deposit date: 2017-12-19 Release date: 2019-02-27 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.94 Å) Cite: Structural evidence for product stabilization by the ribosomal mRNA helicase. Rna, 25, 2019
5TN0	Solution Structure of the N-terminal DNA-binding domain of the master biofilm-regulator SinR from Bacillus subtilis Descriptor: HTH-type transcriptional regulator SinR Authors: Draughn, G.L, Bobay, B.G, Stowe, S.D, Thompson, R.J, Cavanagh, J. Deposit date: 2016-10-13 Release date: 2017-10-25 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis. J.Mol.Biol., 2019
7ESE	The Crystal Structure of human DHFR from Biortus Descriptor: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Wang, F, Cheng, W, Xu, C, Qi, J, Bao, X, Miao, Q. Deposit date: 2021-05-10 Release date: 2021-05-26 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.85 Å) Cite: The Crystal Structure of human DHFR from Biortus To Be Published
6Y08	Mouse thymidylate synthase cocrystallized with dUMP and soaked in sulfamethoxazole Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Sulfamethoxazole, Thymidylate synthase Authors: Maj, P, Jarmula, A, Wilk, P, Weiss, M.S, Rode, W. Deposit date: 2020-02-06 Release date: 2021-02-17 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.297 Å) Cite: Mouse thymidylate synthase cocrystallized with dUMP and soaked in sulfamethoxazole To Be Published
7FEW	Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin gold analogues Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cAMP-activated global transcriptional regulator Vfr Authors: Chew, B.L.A, Luo, D. Deposit date: 2021-07-22 Release date: 2022-07-27 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr. Comput Struct Biotechnol J, 21, 2023

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