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2VXL
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Screening a Limited Structure-based Library Identifies UDP-GalNAc- Specific Mutants of alpha-1,3 Galactosyltransferase
Descriptor: MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE
Authors:Tumbale, P, Jamaluddin, H, Thiyagarajan, N, Acharya, K.R, Brew, K.
Deposit date:2008-07-07
Release date:2008-09-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Screening a Limited Structure-Based Library Identifies Udp-Galnac-Specific Mutants of {Alpha}-1,3-Galactosyltransferase.
Glycobiology, 18, 2008
6K7J
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Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ATP state class1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Cell cycle control protein 50A, ...
Authors:Hiraizumi, M, Yamashita, K, Nishizawa, T, Nureki, O.
Deposit date:2019-06-07
Release date:2019-08-28
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Cryo-EM structures capture the transport cycle of the P4-ATPase flippase.
Science, 365, 2019
2VZ1
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Premat-galactose oxidase
Descriptor: ACETATE ION, CALCIUM ION, GALACTOSE OXIDASE
Authors:Rogers, M.S, Hurtado-Guerrero, R, Firbank, S.J, Halcrow, M.A, Dooley, D.M, Phillips, S.E.V, Knowles, P.F, McPherson, M.J.
Deposit date:2008-07-29
Release date:2008-09-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Cross-Link Formation of the Cysteine 228-Tyrosine 272 Catalytic Cofactor of Galactose Oxidase Does not Require Dioxygen.
Biochemistry, 47, 2008
6K7Y
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Intact human mitochondrial calcium uniporter complex with MICU1/MICU2 subunits
Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, CALCIUM ION, CARDIOLIPIN, ...
Authors:Zhuo, W, Zhou, H, Yang, M.
Deposit date:2019-06-10
Release date:2020-09-09
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of intact human MCU supercomplex with the auxiliary MICU subunits.
Protein Cell, 12, 2021
2VY2
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BU of 2vy2 by Molmil
Structure of LEAFY transcription factor from Arabidopsis thaliana in complex with DNA from AG-I promoter
Descriptor: 5'-D(*AP*TP*TP*TP*AP*AP*TP*CP*CP*AP *AP*TP*GP*GP*TP*TP*AP*CP*AP*A)-3', PROTEIN LEAFY
Authors:Hames, C, Ptchelkine, D, Grimm, C, Thevenon, E, Moyroud, E, Gerard, F, Martiel, J.L, Benlloch, R, Parcy, F, Muller, C.W.
Deposit date:2008-07-16
Release date:2008-09-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for Leafy Floral Switch Function and Similarity with Helix-Turn-Helix Proteins.
Embo J., 27, 2008
1YQD
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BU of 1yqd by Molmil
Sinapyl Alcohol Dehydrogenase complexed with NADP+
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Bomati, E.K, Noel, J.P.
Deposit date:2005-02-01
Release date:2005-07-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural and Kinetic Basis for Substrate Selectivity in Populus tremuloides Sinapyl Alcohol Dehydrogenase.
Plant Cell, 17, 2005
1YQX
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Sinapyl Alcohol Dehydrogenase at 2.5 Angstrom Resolution
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ZINC ION, sinapyl alcohol dehydrogenase
Authors:Bomati, E.K, Noel, J.P.
Deposit date:2005-02-02
Release date:2005-07-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Kinetic Basis for Substrate Selectivity in Populus tremuloides Sinapyl Alcohol Dehydrogenase.
Plant Cell, 17, 2005
6KAM
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BU of 6kam by Molmil
Crystal structure of FKRP in complex with Ba ion, CDP-ribtol, and sugar acceptor
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, BARIUM ION, ...
Authors:Kuwabara, N.
Deposit date:2019-06-23
Release date:2020-01-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Crystal structures of fukutin-related protein (FKRP), a ribitol-phosphate transferase related to muscular dystrophy.
Nat Commun, 11, 2020
6KIG
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BU of 6kig by Molmil
Structure of cyanobacterial photosystem I-IsiA supercomplex
Descriptor: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
Authors:Cao, P, Cao, D.F, Si, L, Su, X.D, Chang, W.R, Liu, Z.F, Zhang, X.Z, Li, M.
Deposit date:2019-07-18
Release date:2020-02-12
Last modified:2020-03-04
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for energy and electron transfer of the photosystem I-IsiA-flavodoxin supercomplex.
Nat.Plants, 6, 2020
2Z3I
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BU of 2z3i by Molmil
Crystal structure of blasticidin S deaminase (BSD) mutant E56Q complexed with substrate
Descriptor: BLASTICIDIN S, Blasticidin-S deaminase, CACODYLATE ION, ...
Authors:Kumasaka, T, Yamamoto, M, Furuichi, M, Nakasako, M, Kimura, M, Yamaguchi, I, Ueki, T.
Deposit date:2007-06-04
Release date:2007-10-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of blasticidin S deaminase (BSD): implications for dynamic properties of catalytic zinc
J.Biol.Chem., 282, 2007
1YPC
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BU of 1ypc by Molmil
DIRECT OBSERVATION OF BETTER HYDRATION AT THE N-TERMINUS OF AN ALPHA-HELIX WITH GLYCINE RATHER THAN ALANINE AS N-CAP
Descriptor: CHYMOTRYPSIN INHIBITOR 2
Authors:Harpaz, Y, Elmasry, N, Fersht, A.R, Henrick, K.
Deposit date:1993-01-10
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Direct observation of better hydration at the N terminus of an alpha-helix with glycine rather than alanine as the N-cap residue.
Proc.Natl.Acad.Sci.USA, 91, 1994
6KDN
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BU of 6kdn by Molmil
HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:dGTP ternary complex
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ...
Authors:Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K.
Deposit date:2019-07-02
Release date:2020-03-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine.
Sci Rep, 10, 2020
2VUP
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BU of 2vup by Molmil
Crystal structure of a type II tryparedoxin-dependant peroxidase from Trypanosoma brucei
Descriptor: GLUTATHIONE PEROXIDASE-LIKE PROTEIN
Authors:Alphey, M.S, Konig, J, Fairlamb, A.H.
Deposit date:2008-05-28
Release date:2008-06-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Mechanistic Insights Into Type II Trypanosomatid Tryparedoxin-Dependent Peroxidases.
Biochem.J., 414, 2008
3KLI
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BU of 3kli by Molmil
Crystal structure of unliganded AZT-resistant HIV-1 Reverse Transcriptase
Descriptor: Reverse transcriptase/ribonuclease H, p51 RT
Authors:Tu, X, Sarafianos, S.G, Arnold, E.
Deposit date:2009-11-08
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis of HIV-1 resistance to AZT by excision.
Nat.Struct.Mol.Biol., 17, 2010
3KNF
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BU of 3knf by Molmil
Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum
Descriptor: D-tyrosyl-tRNA(Tyr) deacylase
Authors:Manickam, Y, Bhatt, T.K, Sharma, A.
Deposit date:2009-11-12
Release date:2009-12-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase
J.Biol.Chem., 285, 2010
2Z4E
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BU of 2z4e by Molmil
Crystal Structure of D-Dimer from Human Fibrin Complexed with Gly-His-Arg-Pro-Tyr-amide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Doolittle, R.F, Pandi, L.
Deposit date:2007-06-16
Release date:2007-10-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
Biochemistry, 46, 2007
2Z5J
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BU of 2z5j by Molmil
Free Transportin 1
Descriptor: Transportin-1
Authors:Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M.
Deposit date:2007-07-13
Release date:2007-10-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
1YO1
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BU of 1yo1 by Molmil
Proton Transfer from His200 in Human Carbonic Anhydrase II
Descriptor: Carbonic anhydrase II, SULFATE ION, ZINC ION
Authors:Bhatt, D, Tu, C, Fisher, S.Z, Hernandez Prada, J.A, McKenna, R, Silverman, D.N.
Deposit date:2005-01-26
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Proton transfer in a Thr200His mutant of human carbonic anhydrase II
Proteins, 61, 2005
1YPB
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BU of 1ypb by Molmil
DIRECT OBSERVATION OF BETTER HYDRATION AT THE N-TERMINUS OF AN ALPHA-HELIX WITH GLYCINE RATHER THAN ALANINE AS N-CAP
Descriptor: CHYMOTRYPSIN INHIBITOR 2
Authors:Harpaz, Y, Elmasry, N, Fersht, A.R, Henrick, K.
Deposit date:1993-01-10
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Direct observation of better hydration at the N terminus of an alpha-helix with glycine rather than alanine as the N-cap residue.
Proc.Natl.Acad.Sci.USA, 91, 1994
2WET
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BU of 2wet by Molmil
Crystal structure of tryptophan 5-halogenase (PyrH) complex with FAD (tryptophan)
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
Authors:De Laurentis, W, Zhu, X, Naismith, J.H.
Deposit date:2009-04-01
Release date:2009-04-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Insights in the Regioselectivity in the Enzymatic Chlorination of Tryptophan.
J.Mol.Biol., 391, 2009
2VUL
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BU of 2vul by Molmil
Thermostable mutant of ENVIRONMENTALLY ISOLATED GH11 XYLANASE
Descriptor: DODECAETHYLENE GLYCOL, GH11 XYLANASE, SULFATE ION
Authors:Dumon, C, Varvak, A, Wall, M.A, Flint, J.E, Lewis, R.J, Lakey, J.H, Luginbuhl, P, Healey, S, Todaro, T, Desantis, G, Sun, M, Parra-Gessert, L, Tan, X, Weiner, D.P, Gilbert, H.J.
Deposit date:2008-05-27
Release date:2008-06-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Engineering Hyperthermostability Into a Gh11 Xylanase is Mediated by Subtle Changes to Protein Structure.
J.Biol.Chem., 283, 2008
6K7O
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BU of 6k7o by Molmil
Complex structure of LILRB4 and h128-3 antibody
Descriptor: Leukocyte immunoglobulin-like receptor subfamily B member 4, h128-3 Fab heavy chain, h128-3 Fab light chain
Authors:Song, H, Chai, Y, Xu, X, Gao, F.G.
Deposit date:2019-06-08
Release date:2019-07-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.004 Å)
Cite:Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development.
Cancer Immunol Res, 7, 2019
1YSG
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BU of 1ysg by Molmil
Solution Structure of the Anti-apoptotic Protein Bcl-xL in Complex with "SAR by NMR" Ligands
Descriptor: 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID, 5,6,7,8-TETRAHYDRONAPHTHALEN-1-OL, Apoptosis regulator Bcl-X
Authors:Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H.
Deposit date:2005-02-08
Release date:2005-06-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
1YUK
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BU of 1yuk by Molmil
The crystal structure of the PSI/Hybrid domain/ I-EGF1 segment from the human integrin beta2 at 1.8 resolution
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, Integrin beta-2 A chain, Integrin beta-2 B chain
Authors:Shi, M, Sundramurthy, K, Liu, B, Tan, S.M, Law, S.K, Lescar, J.
Deposit date:2005-02-14
Release date:2005-07-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin {beta}2 Subunit at 1.8-A Resolution
J.Biol.Chem., 280, 2005
2YJF
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BU of 2yjf by Molmil
Oligomeric assembly of actin bound to MRTF-A
Descriptor: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Mouilleron, S, Langer, C.A, Guettler, S, McDonald, N.Q, Treisman, R.
Deposit date:2011-05-19
Release date:2011-07-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of a pentavalent G-actin*MRTF-A complex reveals how G-actin controls nucleocytoplasmic shuttling of a transcriptional coactivator.
Sci Signal, 4, 2011

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