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7FAG
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BU of 7fag by Molmil
Room temperature structure of elastase with high-strength agarose hydrogel
Descriptor: CALCIUM ION, Chymotrypsin-like elastase family member 1, SULFATE ION, ...
Authors:Sugiyama, S, Kakinouchi, K, Adachi, H, Murata, M, Mori, Y.
Deposit date:2021-07-06
Release date:2022-07-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Room temperature structure of elastase with high-strength agarose hydrogel
To Be Published
2LPR
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BU of 2lpr by Molmil
STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-VALINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Bone, R, Agard, D.A.
Deposit date:1991-08-05
Release date:1993-01-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
9LPR
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BU of 9lpr by Molmil
STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Bone, R, Agard, D.A.
Deposit date:1991-08-05
Release date:1993-01-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
5SGA
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BU of 5sga by Molmil
Structures of product and inhibitor complexes of Streptomyces griseus protease a at 1.8 Angstroms resolution. a model for serine protease catalysis
Descriptor: PROTEINASE A (SGPA), TETRAPEPTIDE ACE-PRO-ALA-PRO-TYR
Authors:Sielecki, A.R, James, M.N.G.
Deposit date:1990-05-29
Release date:1991-10-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 A resolution. A model for serine protease catalysis.
J.Mol.Biol., 144, 1980
6R7U
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BU of 6r7u by Molmil
Selenomethionine variant of Tannerella forsythia promirolysin mutant E225A
Descriptor: BORIC ACID, CALCIUM ION, GLYCEROL, ...
Authors:Rodriguez-Banqueri, A, Guevara, T, Ksiazek, M, Potempa, J, Gomis-Ruth, F.X.
Deposit date:2019-03-29
Release date:2020-02-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-based mechanism of cysteine-switch latency and of catalysis by pappalysin-family metallopeptidases.
Iucrj, 7, 2020
6R7V
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BU of 6r7v by Molmil
Tannerella forsythia promirolysin mutant E225A
Descriptor: CALCIUM ION, GLYCEROL, Mirolysin, ...
Authors:Rodriguez-Banqueri, A, Guevara, T, Ksiazek, M, Potempa, J, Gomis-Ruth, F.X.
Deposit date:2019-03-29
Release date:2019-11-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure-based mechanism of cysteine-switch latency and of catalysis by pappalysin-family metallopeptidases.
Iucrj, 7, 2020
6R8X
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BU of 6r8x by Molmil
COAGULATION FACTOR XI CATALYTIC DOMAIN IN COMPLEX WITH FAB-PORTION OF MAA868
Descriptor: Coagulation factor XI, anti-Factor-XI Fab fragment heavy chain MAA868, anti-Factor-XI Fab fragment light chain MAA868
Authors:Schiering, N, Koch, A.
Deposit date:2019-04-02
Release date:2019-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:MAA868, a novel FXI antibody with a unique binding mode, shows durable effects on markers of anticoagulation in humans.
Blood, 133, 2019
6TH7
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BU of 6th7 by Molmil
Structure of porcine pancreatic elastase in complex with tutuilamide
Descriptor: CALCIUM ION, Chymotrypsin-like elastase family member 1, Tutuilamide
Authors:Koehnke, J, Sikandar, A.
Deposit date:2019-11-18
Release date:2020-03-04
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Tutuilamides A-C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties.
Acs Chem.Biol., 15, 2020
8A7P
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BU of 8a7p by Molmil
beta-2-microglobulin DeltaN6 amyloid fibril form 2PFb
Descriptor: Beta-2-microglobulin form pI 5.3
Authors:Wilkinson, M, Gallardo, R, Radford, S.E, Ranson, N.A.
Deposit date:2022-06-21
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Disease-relevant beta 2 -microglobulin variants share a common amyloid fold.
Nat Commun, 14, 2023
6TNA
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BU of 6tna by Molmil
CRYSTAL STRUCTURE OF YEAST PHENYLALANINE T-RNA. I.CRYSTALLOGRAPHIC REFINEMENT
Descriptor: MAGNESIUM ION, TRNAPHE
Authors:Sussman, J.L, Holbrook, S.R, Warrant, R.W, Church, G.M, Kim, S.-H.
Deposit date:1978-11-16
Release date:1979-01-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of yeast phenylalanine transfer RNA. I. Crystallographic refinement.
J.Mol.Biol., 123, 1978
1HLT
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BU of 1hlt by Molmil
THE STRUCTURE OF A NONADECAPEPTIDE OF THE FIFTH EGF DOMAIN OF THROMBOMODULIN COMPLEXED WITH THROMBIN
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ...
Authors:Tulinsky, A, Mathews, I.I.
Deposit date:1994-08-28
Release date:1994-12-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of a nonadecapeptide of the fifth EGF domain of thrombomodulin complexed with thrombin.
Biochemistry, 33, 1994
8BT6
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BU of 8bt6 by Molmil
Crystal structure of Toxoplasma gondii glideosome-associated connector
Descriptor: ACETATE ION, POTASSIUM ION, Putative anonymous antigen-1
Authors:Hung, Y.F, Kursula, I.
Deposit date:2022-11-27
Release date:2023-04-05
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structure of Toxoplasma gondii glideosome-associated connector suggests a role as an elastic element to assist myosin A in generating force for gliding motility
To Be Published
3LUN
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BU of 3lun by Molmil
Structure of ulilysin mutant M290C
Descriptor: ARGININE, CALCIUM ION, GLYCEROL, ...
Authors:Tallant, C, Garcia-Castellanos, R, Baumann, U, Gomis-Ruth, F.X.
Deposit date:2010-02-18
Release date:2010-03-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:On the relevance of the Met-turn methionine in metzincins.
J.Biol.Chem., 285, 2010
3LPR
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BU of 3lpr by Molmil
STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-NORLEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Bone, R, Agard, D.A.
Deposit date:1991-08-05
Release date:1993-01-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
3SGB
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BU of 3sgb by Molmil
STRUCTURE OF THE COMPLEX OF STREPTOMYCES GRISEUS PROTEASE B AND THE THIRD DOMAIN OF THE TURKEY OVOMUCOID INHIBITOR AT 1.8 ANGSTROMS RESOLUTION
Descriptor: PROTEINASE B (SGPB), TURKEY OVOMUCOID INHIBITOR (OMTKY3)
Authors:Read, R.J, Fujinaga, M, Sielecki, A.R, James, M.N.G.
Deposit date:1983-01-21
Release date:1983-07-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the complex of Streptomyces griseus protease B and the third domain of the turkey ovomucoid inhibitor at 1.8-A resolution.
Biochemistry, 22, 1983
7Q64
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BU of 7q64 by Molmil
Cryo-em structure of the Nup98 fibril polymorph 1
Descriptor: Nuclear pore complex protein Nup98
Authors:Ibanez de Opakua, A, Geraets, J.A, Frieg, B, Dienemann, C, Savastano, A, Rankovic, M, Cima-Omori, M.-S, Schroeder, G.F, Zweckstetter, M.
Deposit date:2021-11-05
Release date:2022-10-12
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Molecular interactions of FG nucleoporin repeats at high resolution.
Nat.Chem., 14, 2022
7Q65
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BU of 7q65 by Molmil
Cryo-em structure of the Nup98 fibril polymorph 2
Descriptor: Nuclear pore complex protein Nup98
Authors:Ibanez de Opakua, A, Geraets, J.A, Frieg, B, Dienemann, C, Savastano, A, Rankovic, M, Cima-Omori, M.-S, Schroeder, G.F, Zweckstetter, M.
Deposit date:2021-11-05
Release date:2022-10-12
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Molecular interactions of FG nucleoporin repeats at high resolution.
Nat.Chem., 14, 2022
7Q67
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BU of 7q67 by Molmil
Cryo-em structure of the Nup98 fibril polymorph 4
Descriptor: Nuclear pore complex protein Nup98
Authors:Ibanez de Opakua, A, Geraets, J.A, Frieg, B, Dienemann, C, Savastano, A, Rankovic, M, Cima-Omori, M.-S, Schroeder, G.F, Zweckstetter, M.
Deposit date:2021-11-05
Release date:2022-10-12
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Molecular interactions of FG nucleoporin repeats at high resolution.
Nat.Chem., 14, 2022
6JDX
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BU of 6jdx by Molmil
Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9 preprocessed with protease alpha-Chymotrypsin
Descriptor: 1,2-ETHANEDIOL, AcrIIC2, CRISPR-associated endonuclease Cas9
Authors:Cheng, Z, Huang, X, Sun, W, Wang, Y.
Deposit date:2019-02-02
Release date:2019-05-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
4K1T
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BU of 4k1t by Molmil
Gly-Ser-SplB protease from Staphylococcus aureus at 1.60 A resolution
Descriptor: CHLORIDE ION, SULFATE ION, Serine protease SplB, ...
Authors:Zdzalik, M, Pustelny, K, Stec-Niemczyk, J, Cichon, P, Czarna, A, Popowicz, G, Drag, M, Wladyka, B, Potempa, J, Dubin, A, Dubin, G.
Deposit date:2013-04-05
Release date:2014-04-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Staphylococcal SplB Serine Protease Utilizes a Novel Molecular Mechanism of Activation.
J.Biol.Chem., 289, 2014
1TAL
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BU of 1tal by Molmil
ALPHA-LYTIC PROTEASE AT 120 K (SINGLE STRUCTURE MODEL)
Descriptor: ALPHA-LYTIC PROTEASE, SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE
Authors:Rader, S.D, Agard, D.A.
Deposit date:1996-10-30
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conformational substates in enzyme mechanism: the 120 K structure of alpha-lytic protease at 1.5 A resolution.
Protein Sci., 6, 1997
8FNJ
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BU of 8fnj by Molmil
Structure of E138K/G140A HIV-1 intasome with Dolutegravir bound
Descriptor: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ...
Authors:Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D.
Deposit date:2022-12-27
Release date:2023-08-09
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants.
Sci Adv, 9, 2023
8FNN
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BU of 8fnn by Molmil
Structure of E138K/G140A/Q148K HIV-1 intasome with Dolutegravir bound
Descriptor: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ...
Authors:Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D.
Deposit date:2022-12-27
Release date:2023-08-09
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants.
Sci Adv, 9, 2023
8FN7
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BU of 8fn7 by Molmil
Structure of WT HIV-1 intasome bound to Dolutegravir
Descriptor: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ...
Authors:Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D.
Deposit date:2022-12-27
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants.
Sci Adv, 9, 2023
8FNL
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BU of 8fnl by Molmil
Structure of E138K/Q148K HIV-1 intasome with Dolutegravir bound
Descriptor: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ...
Authors:Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D.
Deposit date:2022-12-27
Release date:2023-08-09
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants.
Sci Adv, 9, 2023

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