6R7V

Tannerella forsythia promirolysin mutant E225A

Summary for 6R7V

Related6R7U
DescriptorMirolysin, CALCIUM ION, ZINC ION, ... (5 entities in total)
Functional Keywordsmetallopeptidase zymogen, metzincin, pappalysin family, tannerella forsythia, periodontopathogen, periodontal disease, hydrolase
Biological sourceTannerella forsythia
Total number of polymer chains1
Total molecular weight35889.03
Authors
Rodriguez-Banqueri, A.,Guevara, T.,Ksiazek, M.,Potempa, J.,Gomis-Ruth, F.X. (deposition date: 2019-03-29, release date: 2019-11-13, Last modification date: 2020-01-29)
Primary citation
Guevara, T.,Rodriguez-Banqueri, A.,Ksiazek, M.,Potempa, J.,Gomis-Ruth, F.X.
Structure-based mechanism of cysteine-switch latency and of catalysis by pappalysin-family metallopeptidases.
Iucrj, 7:18-29, 2020
PubMed: 31949901 (PDB entries with the same primary citation)
DOI: 10.1107/S2052252519013848
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2022 1.0% 1.5% 2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload