6TH7

Structure of porcine pancreatic elastase in complex with tutuilamide

Summary for 6TH7

• Entry DOI: 10.2210/pdb6th7/pdb
• Descriptor: Chymotrypsin-like elastase family member 1, Tutuilamide, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: elastase, inhibitor, hydrolase
• Biological source: Sus scrofa (pig); More
• Total number of polymer chains: 4
• Total formula weight: 53897.47

Authors

Koehnke, J.,Sikandar, A. (deposition date: 2019-11-18, release date: 2020-03-04, Last modification date: 2024-01-31)

• Primary citation: Keller, L.,Canuto, K.M.,Liu, C.,Suzuki, B.M.,Almaliti, J.,Sikandar, A.,Naman, C.B.,Glukhov, E.,Luo, D.,Duggan, B.M.,Luesch, H.,Koehnke, J.,O'Donoghue, A.J.,Gerwick, W.H.; Tutuilamides A-C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties.; Acs Chem.Biol., 15:751-757, 2020; PubMed: 31935054; DOI: 10.1021/acschembio.9b00992

Experimental method

X-RAY DIFFRACTION (2.2 Å)