Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0006508 | biological_process | proteolysis |
| B | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 301 |
| Chain | Residue |
| A | GLU85 |
| A | ASN87 |
| A | GLN90 |
| A | ASP92 |
| A | GLU95 |
| A | HOH501 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 301 |
| Chain | Residue |
| B | ASP92 |
| B | GLU95 |
| B | GLU85 |
| B | ASN87 |
| B | GLN90 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide ABA A 301 and ILE A 306 |
| Chain | Residue |
| A | HIS71 |
| A | VAL114 |
| A | SER233 |
| A | PHE234 |
| A | VAL235 |
| A | SER236 |
| A | ARG237 |
| C | VAL302 |
| C | 5XU309 |
| C | N9K303 |
| C | AA4305 |
| C | ABA306 |
| C | HOH401 |
| C | HOH403 |
| C | HOH405 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for residues ABA A 301 and ABA A 310 |
| Chain | Residue |
| A | HIS71 |
| A | VAL114 |
| A | GLN211 |
| A | GLY212 |
| A | SER214 |
| A | SER233 |
| A | PHE234 |
| A | VAL235 |
| C | VAL302 |
| C | ILE308 |
| C | AA4305 |
| C | HOH401 |
| C | HOH403 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide ABA A 301 and VAL A 302 |
| Chain | Residue |
| A | HIS71 |
| A | VAL114 |
| A | SER233 |
| C | ILE308 |
| C | N9K303 |
| C | AA4305 |
| C | ABA306 |
| C | HOH401 |
| C | HOH403 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide VAL A 302 and N9K A 307 |
| Chain | Residue |
| A | HIS71 |
| A | PRO107 |
| A | TRP258 |
| C | ABA307 |
| C | ILE308 |
| C | PHE304 |
| C | AA4305 |
| C | HOH402 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residues O4Q A 304 and 5XU A 305 |
| Chain | Residue |
| A | PHE234 |
| A | VAL235 |
| A | SER236 |
| A | ARG237 |
| C | ILE308 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide 5XU A 305 and ILE A 306 |
| Chain | Residue |
| A | PHE234 |
| A | VAL235 |
| A | SER236 |
| A | ARG237 |
| C | ABA307 |
| C | O4Q310 |
| C | N9K303 |
| C | ABA306 |
| C | HOH405 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residues N9K A 307 and PHA A 308 |
| Chain | Residue |
| A | PRO107 |
| A | GLN211 |
| A | GLY212 |
| A | TRP258 |
| C | VAL302 |
| C | ILE308 |
| C | AA4305 |
| C | HOH402 |
| site_id | AD1 |
| Number of Residues | 12 |
| Details | binding site for residues PHA A 308 and AA4 A 309 |
| Chain | Residue |
| A | THR55 |
| A | HIS71 |
| A | PRO107 |
| A | GLN211 |
| A | GLY212 |
| A | SER214 |
| C | ABA307 |
| C | VAL302 |
| C | N9K303 |
| C | ABA306 |
| C | HOH401 |
| C | HOH404 |
| site_id | AD2 |
| Number of Residues | 12 |
| Details | binding site for residues PHA A 308 and AA4 A 309 |
| Chain | Residue |
| C | ABA306 |
| C | HOH401 |
| C | HOH404 |
| A | THR55 |
| A | HIS71 |
| A | PRO107 |
| A | GLN211 |
| A | GLY212 |
| A | SER214 |
| C | ABA307 |
| C | VAL302 |
| C | N9K303 |
| site_id | AD3 |
| Number of Residues | 15 |
| Details | binding site for residues AA4 A 309 and ABA A 310 |
| Chain | Residue |
| A | THR55 |
| A | HIS71 |
| A | GLN211 |
| A | GLY212 |
| A | SER214 |
| A | SER233 |
| A | PHE234 |
| A | VAL235 |
| C | ABA307 |
| C | VAL302 |
| C | ILE308 |
| C | N9K303 |
| C | PHE304 |
| C | HOH401 |
| C | HOH404 |
| site_id | AD4 |
| Number of Residues | 12 |
| Details | binding site for residues ABA B 301 and ABA B 310 |
| Chain | Residue |
| B | HIS71 |
| B | VAL114 |
| B | GLN211 |
| B | GLY212 |
| B | SER214 |
| B | SER233 |
| B | VAL235 |
| D | VAL314 |
| D | ILE316 |
| D | AA4311 |
| B | HOH420 |
| D | HOH401 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide ABA B 301 and VAL B 302 |
| Chain | Residue |
| B | HIS71 |
| B | VAL114 |
| B | SER233 |
| D | ILE316 |
| D | YNM313 |
| D | AA4311 |
| D | ABA310 |
| D | HOH401 |
| site_id | AD6 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide ABA B 301 and ILE B 306 |
| Chain | Residue |
| A | ALA126 |
| A | GLN127 |
| B | HIS71 |
| B | VAL114 |
| B | SER233 |
| B | PHE234 |
| B | VAL235 |
| D | VAL314 |
| D | 5XU317 |
| D | YNM313 |
| D | AA4311 |
| D | ABA310 |
| D | HOH401 |
| site_id | AD7 |
| Number of Residues | 10 |
| Details | binding site for Di-peptide VAL B 302 and YNM B 307 |
| Chain | Residue |
| A | PHE79 |
| A | GLY99 |
| A | VAL100 |
| B | HIS71 |
| D | ABA315 |
| D | ILE316 |
| D | PHE312 |
| D | AA4311 |
| D | ABA310 |
| D | HOH402 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residues O4Q B 304 and 5XU B 305 |
| Chain | Residue |
| B | TRP190 |
| B | PHE234 |
| B | VAL235 |
| B | SER236 |
| B | ARG237 |
| D | ILE316 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide 5XU B 305 and ILE B 306 |
| Chain | Residue |
| A | ALA126 |
| A | GLN127 |
| B | PHE234 |
| B | VAL235 |
| D | ABA315 |
| D | O4Q318 |
| D | YNM313 |
| D | ABA310 |
| site_id | AE1 |
| Number of Residues | 10 |
| Details | binding site for residues YNM B 307 and PHA B 308 |
| Chain | Residue |
| A | ARG47 |
| A | PHE79 |
| A | GLY99 |
| A | VAL100 |
| B | THR55 |
| B | GLY212 |
| D | VAL314 |
| D | ILE316 |
| D | AA4311 |
| D | HOH402 |
| site_id | AE2 |
| Number of Residues | 11 |
| Details | binding site for residues PHA B 308 and AA4 B 309 |
| Chain | Residue |
| A | ARG47 |
| B | THR55 |
| B | HIS71 |
| B | GLN211 |
| B | GLY212 |
| B | SER214 |
| D | ABA315 |
| D | VAL314 |
| D | YNM313 |
| D | ABA310 |
| D | HOH401 |
| site_id | AE3 |
| Number of Residues | 11 |
| Details | binding site for residues PHA B 308 and AA4 B 309 |
| Chain | Residue |
| A | ARG47 |
| B | THR55 |
| B | HIS71 |
| B | GLN211 |
| B | GLY212 |
| B | SER214 |
| D | ABA315 |
| D | VAL314 |
| D | YNM313 |
| D | ABA310 |
| D | HOH401 |
| site_id | AE4 |
| Number of Residues | 14 |
| Details | binding site for residues AA4 B 309 and ABA B 310 |
| Chain | Residue |
| B | THR55 |
| B | HIS71 |
| B | GLN211 |
| B | GLY212 |
| B | SER214 |
| B | SER233 |
| B | VAL235 |
| D | ABA315 |
| D | VAL314 |
| D | ILE316 |
| D | YNM313 |
| D | PHE312 |
| B | HOH420 |
| D | HOH401 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. MTAAHC |
| Chain | Residue | Details |
| A | MET67-CYS72 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. SGcqGDSGGPLH |
| Chain | Residue | Details |
| A | SER208-HIS219 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS71 | |
| B | HIS71 | |
| Chain | Residue | Details |
| A | ASP119 | |
| A | SER214 | |
| B | ASP119 | |
| B | SER214 | |
| Chain | Residue | Details |
| A | GLU85 | |
| A | ASN87 | |
| A | GLN90 | |
| A | GLU95 | |
| B | GLU85 | |
| B | ASN87 | |
| B | GLN90 | |
| B | GLU95 | |
