PDB: 1901 resultsInfo pagesStatus searchChemie searchBIRD

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4F8C	Structure of the Cif:Nedd8 complex - Yersinia pseudotuberculosis Cycle Inhibiting Factor in complex with human Nedd8 Descriptor: 1,2-ETHANEDIOL, Cycle Inhibiting Factor, NEDD8 Authors: Crow, A, Banfield, M. Deposit date: 2012-05-17 Release date: 2012-06-20 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.95 Å) Cite: The molecular basis of Nedd8 deamidation by the bacterial effector protein Cif Proc.Natl.Acad.Sci.USA, 2012
2R3I	Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor Descriptor: 5-(2-fluorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine, Cell division protein kinase 2 Authors: Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S. Deposit date: 2007-08-29 Release date: 2008-01-22 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.28 Å) Cite: Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers, 89, 2008
2R3M	Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor Descriptor: Cell division protein kinase 2, N-((2-aminopyrimidin-5-yl)methyl)-5-(2,6-difluorophenyl)-3-ethylpyrazolo[1,5-a]pyrimidin-7-amine Authors: Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S. Deposit date: 2007-08-29 Release date: 2008-01-22 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers, 89, 2008
2R3Q	Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor Descriptor: 3-((3-bromo-5-o-tolylpyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxide, Cell division protein kinase 2 Authors: Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S. Deposit date: 2007-08-29 Release date: 2008-01-22 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers, 89, 2008
2R3R	Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor Descriptor: 3-bromo-5-phenyl-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine, Cell division protein kinase 2 Authors: Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S. Deposit date: 2007-08-29 Release date: 2008-01-22 Last modified: 2021-07-28 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers, 89, 2008
2R3J	Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor Descriptor: 3-bromo-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine, Cell division protein kinase 2 Authors: Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S. Deposit date: 2007-08-29 Release date: 2008-01-22 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers, 89, 2008
2R3H	Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor Descriptor: 3-methyl-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine, Cell division protein kinase 2 Authors: Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S. Deposit date: 2007-08-29 Release date: 2008-01-22 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers, 89, 2008
2R3L	Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor Descriptor: 3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine, Cell division protein kinase 2 Authors: Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S. Deposit date: 2007-08-29 Release date: 2008-01-22 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers, 89, 2008
6HG4	Crystal Structure of the human IL-17RC ECD in complex with human IL-17F Descriptor: Interleukin-17 receptor C, Interleukin-17F Authors: Rondeau, J.M, Goepfert, A. Deposit date: 2018-08-22 Release date: 2020-03-18 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.32 Å) Cite: Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling. Immunity, 52, 2020
6HG9	Crystal Structure of the human IL-17RC ECD in complex with human IL-17F, Crystal form II Descriptor: Interleukin-17 receptor C, Interleukin-17F Authors: Rondeau, J.M, Goepfert, A. Deposit date: 2018-08-23 Release date: 2020-03-18 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.62 Å) Cite: Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling. Immunity, 52, 2020
6WNX	FBXW11-SKP1 in complex with a pSer33/pSer37 Beta-Catenin peptide Descriptor: Catenin beta-1, F-box/WD repeat-containing protein 11, GLYCEROL, ... Authors: Ivanochko, D, Edwards, A.M, Bountra, C, Arrowsmith, C.H, Boettcher, J, Structural Genomics Consortium (SGC) Deposit date: 2020-04-23 Release date: 2020-05-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.5 Å) Cite: FBXW11-SKP1 in complex with a pSer33/pSer37 Beta-Catenin peptide To Be Published
1PUE	PU.1 ETS DOMAIN-DNA COMPLEX Descriptor: DNA (5'-D(*AP*AP*AP*AP*AP*GP*GP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*CP*CP*TP*TP*TP*T)-3'), PROTEIN (TRANSCRIPTION FACTOR PU.1 (TF PU.1)) Authors: Kodandapani, R, Pio, F, Ni, C.Z, Piccialli, G, Klemsz, M, McKercher, S, Maki, R.A, Ely, K.R. Deposit date: 1996-07-08 Release date: 1997-02-12 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A new pattern for helix-turn-helix recognition revealed by the PU.1 ETS-domain-DNA complex. Nature, 380, 1996
6H5H	A computationally designed dRP lyase domain reconstructed from two heterologous fragments Descriptor: polb4 Authors: ElGamacy, M, Coles, M, Lupas, A.N. Deposit date: 2018-07-24 Release date: 2018-12-12 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Asymmetric protein design from conserved supersecondary structures. J. Struct. Biol., 204, 2018
8SV1	Caspase-1 complex with interleukin-18 Descriptor: Caspase-1, Interleukin-18 Authors: Dong, Y, Pascal, D, Jon, K, Wu, H. Deposit date: 2023-05-15 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Caspase-1 complex with interleukin-18 To Be Published
2L7F	Solution Structure of the Pitx2 Homeodomain Descriptor: Pituitary homeobox 2 Authors: Doerdelmann, T, Rance, M, Baird-Titus, J.M, Kojetin, D.J. Deposit date: 2010-12-08 Release date: 2011-12-14 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution Structure of the Pitx2 Homeodomain To be Published
2AST	Crystal structure of Skp1-Skp2-Cks1 in complex with a p27 peptide Descriptor: BENZAMIDINE, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ... Authors: Hao, B, Zhang, N, Schulman, B.A, Wu, G, Pagano, M, Pavletich, N.P. Deposit date: 2005-08-24 Release date: 2005-10-18 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural Basis of the Cks1-Dependent Recognition of p27(Kip1) by the SCF(Skp2) Ubiquitin Ligase. Mol.Cell, 20, 2005
5IBK	Skp1-F-box in complex with a ubiquitin variant Descriptor: F-box/WD repeat-containing protein 7, Polyubiquitin-B, S-phase kinase-associated protein 1,S-phase kinase-associated protein 1 Authors: Orlicky, S, Sicheri, F. Deposit date: 2016-02-22 Release date: 2016-03-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.503 Å) Cite: Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1-F-box interface. Proc.Natl.Acad.Sci.USA, 113, 2016
5K35	Structure of the Legionella effector, AnkB, in complex with human Skp1 Descriptor: Ankyrin-repeat protein B, S-phase kinase-associated protein 1 Authors: Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) Deposit date: 2016-05-19 Release date: 2017-01-25 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Structural Mimicry by a Bacterial F Box Effector Hijacks the Host Ubiquitin-Proteasome System. Structure, 25, 2017
2L7M	Solution Structure of the Pitx2 Homeodomain R24H mutant Descriptor: Pituitary homeobox 2 Authors: Doerdelmann, T, Rance, M, Kojetin, D.J, Baird-Titus, J.M. Deposit date: 2010-12-14 Release date: 2011-12-14 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution Structure of the Pitx2 Homeodomain R24H mutant To be Published
2LKX	NMR structure of the homeodomain of Pitx2 in complex with a TAATCC DNA binding site Descriptor: DNA (5'-D(*CP*GP*GP*GP*GP*AP*TP*TP*AP*GP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*CP*TP*AP*AP*TP*CP*CP*CP*CP*G)-3'), Pituitary homeobox 3 Authors: Baird-Titus, J.M, Doerdelmann, T, Chaney, B.A, Clark-Baldwin, K, Dave, V, Ma, J. Deposit date: 2011-10-21 Release date: 2012-05-02 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution structure of the K50 class homeodomain PITX2 bound to DNA and implications for mutations that cause Rieger syndrome Biochemistry, 44, 2005
2K40	NMR structure of HESX-1 homeodomain double mutant R31L/E42L Descriptor: Homeobox expressed in ES cells 1 Authors: Asensio, J, Torrado, M, Gonzalez, C, Bastida, A. Deposit date: 2008-05-26 Release date: 2009-05-05 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: The role of conserved salt-bridges on homeodomain stability To be Published
2ASS	Crystal structure of the Skp1-Skp2-Cks1 complex Descriptor: BENZAMIDINE, Cyclin-dependent kinases regulatory subunit 1, PHOSPHATE ION, ... Authors: Hao, B, Zhang, N, Schulman, B.A, Wu, G, Pagano, M, Pavletich, N.P. Deposit date: 2005-08-24 Release date: 2005-10-18 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural Basis of the Cks1-Dependent Recognition of p27(Kip1) by the SCF(Skp2) Ubiquitin Ligase. Mol.Cell, 20, 2005
2KG4	Three-dimensional structure of human Gadd45alpha in solution by NMR Descriptor: Growth arrest and DNA-damage-inducible protein GADD45 alpha Authors: Sanchez, R, Pantoja-Uceda, D, Prieto, J, Diercks, T, Campos-Olivas, R, Blanco, F.J. Deposit date: 2009-03-04 Release date: 2009-03-31 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase J.Biol.Chem., 285, 2010
2E31	Structural basis for selection of glycosylated substrate by SCFFbs1 ubiquitin ligase Descriptor: F-box only protein 2, S-phase kinase-associated protein 1A Authors: Mizushima, T, Yoshida, Y, Kumanomidou, T, Hasegawa, Y, Yamane, T, Tanaka, K. Deposit date: 2006-11-20 Release date: 2007-03-20 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase Proc.Natl.Acad.Sci.Usa, 104, 2007
2E32	Structural basis for selection of glycosylated substrate by SCFFbs1 ubiquitin ligase Descriptor: F-box only protein 2, S-phase kinase-associated protein 1A Authors: Mizushima, T, Yoshida, Y, Kumanomidou, T, Hasegawa, Y, Yamane, T, Tanaka, K. Deposit date: 2006-11-20 Release date: 2007-03-20 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.52 Å) Cite: Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase Proc.Natl.Acad.Sci.Usa, 104, 2007

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