6HG9
Crystal Structure of the human IL-17RC ECD in complex with human IL-17F, Crystal form II
Summary for 6HG9
Entry DOI | 10.2210/pdb6hg9/pdb |
Related | 6HG4 |
Descriptor | Interleukin-17F, Interleukin-17 receptor C (2 entities in total) |
Functional Keywords | cystine-knot, fniii domains, receptor-cytokine complex, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 66164.23 |
Authors | Rondeau, J.M.,Goepfert, A. (deposition date: 2018-08-23, release date: 2020-03-18, Last modification date: 2024-01-17) |
Primary citation | Goepfert, A.,Lehmann, S.,Blank, J.,Kolbinger, F.,Rondeau, J.M. Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling. Immunity, 52:499-512.e5, 2020 Cited by PubMed: 32187518DOI: 10.1016/j.immuni.2020.02.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.62 Å) |
Structure validation
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