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6HG9

Crystal Structure of the human IL-17RC ECD in complex with human IL-17F, Crystal form II

Functional Information from GO Data
ChainGOidnamespacecontents
A0001819biological_processpositive regulation of cytokine production
A0002225biological_processpositive regulation of antimicrobial peptide production
A0002250biological_processadaptive immune response
A0005125molecular_functioncytokine activity
A0005126molecular_functioncytokine receptor binding
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006954biological_processinflammatory response
A0016525biological_processnegative regulation of angiogenesis
A0017015biological_processregulation of transforming growth factor beta receptor signaling pathway
A0019955molecular_functioncytokine binding
A0032645biological_processregulation of granulocyte macrophage colony-stimulating factor production
A0032663biological_processregulation of interleukin-2 production
A0032675biological_processregulation of interleukin-6 production
A0032677biological_processregulation of interleukin-8 production
A0032755biological_processpositive regulation of interleukin-6 production
A0032761biological_processpositive regulation of lymphotoxin A production
A0042803molecular_functionprotein homodimerization activity
A0045087biological_processinnate immune response
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0046982molecular_functionprotein heterodimerization activity
A0050829biological_processdefense response to Gram-negative bacterium
A0050830biological_processdefense response to Gram-positive bacterium
A0051216biological_processcartilage development
A0097400biological_processinterleukin-17-mediated signaling pathway
A1900017biological_processpositive regulation of cytokine production involved in inflammatory response
A2000340biological_processpositive regulation of chemokine (C-X-C motif) ligand 1 production
B0030368molecular_functioninterleukin-17 receptor activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues9
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
BGLN118
BGLN186
BGLN213
BGLN226
BASN253
BGLN263
BGLN349
BGLN372
BGLN406

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PDB entries from 2024-07-24

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