4OZ7
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4OSK
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![BU of 4osk by Molmil](/molmil-images/mine/4osk) | Crystal structure of TAL effector reveals the recognition between asparagine and guanine | Descriptor: | DNA (5'-D(*AP*GP*TP*CP*TP*AP*GP*TP*AP*GP*TP*TP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*AP*AP*CP*TP*AP*CP*TP*AP*GP*AP*CP*T)-3'), Hax3 | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | Deposit date: | 2014-02-13 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.398 Å) | Cite: | Revisiting the TALE repeat Protein Cell, 5, 2014
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3UKR
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![BU of 3ukr by Molmil](/molmil-images/mine/3ukr) | Crystal structure of Bos taurus Arp2/3 complex with bound inhibitor CK-666 | Descriptor: | 2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ... | Authors: | Nolen, B.J, Han, M. | Deposit date: | 2011-11-09 | Release date: | 2013-02-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Structural characterization and computer-aided optimization of a small-molecule inhibitor of the Arp2/3 complex, a key regulator of the actin cytoskeleton. Chemmedchem, 7, 2012
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4OZB
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![BU of 4ozb by Molmil](/molmil-images/mine/4ozb) | Backbone Modifications in the Protein GB1 Helix: beta-ACPC24, beta-3-Lys28, beta-3-Lys31, beta-ACPC35 | Descriptor: | GLYCEROL, Streptococcal Protein GB1 Backbone Modified Variant: beta-ACPC24, beta-3-Lys28, ... | Authors: | Reinert, Z.E, Horne, W.S. | Deposit date: | 2014-02-14 | Release date: | 2014-07-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Folding Thermodynamics of Protein-Like Oligomers with Heterogeneous Backbones. Chem Sci, 5, 2014
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3UHC
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![BU of 3uhc by Molmil](/molmil-images/mine/3uhc) | HBI (N79A) CO bound | Descriptor: | CARBON MONOXIDE, Globin-1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Ren, Z, Srajer, V, Knapp, J.E, Royer Jr, W.E. | Deposit date: | 2011-11-03 | Release date: | 2011-12-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures. Proc.Natl.Acad.Sci.USA, 109, 2012
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3UHP
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![BU of 3uhp by Molmil](/molmil-images/mine/3uhp) | Crystal Structure of Glutamate Racemase from Campylobacter jejuni subsp. jejuni | Descriptor: | Glutamate racemase | Authors: | Maltseva, N, Mulligan, R, Kwon, K, Kim, Y, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-11-03 | Release date: | 2012-05-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.794 Å) | Cite: | Crystal Structure of Glutamate Racemase
from Campylobacter jejuni subsp. jejuni To be Published, 2011
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4OT0
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![BU of 4ot0 by Molmil](/molmil-images/mine/4ot0) | Crystal structure of the S505T mutant of TAL effector dHax3 | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | Deposit date: | 2014-02-13 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.491 Å) | Cite: | Revisiting the TALE repeat Protein Cell, 5, 2014
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4OZK
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3UL8
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![BU of 3ul8 by Molmil](/molmil-images/mine/3ul8) | Crystal structure of the TV3 mutant V134L | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Toll-like receptor 4, ... | Authors: | Kim, H.J, Cheong, H.K, Jeon, Y.H. | Deposit date: | 2011-11-10 | Release date: | 2012-04-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein. Plos One, 7, 2012
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2QW7
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![BU of 2qw7 by Molmil](/molmil-images/mine/2qw7) | Carboxysome Subunit, CcmL | Descriptor: | Carbon dioxide concentrating mechanism protein ccmL, GLYCEROL | Authors: | Tanaka, S, Sawaya, M.R, Kerfeld, C.A, Yeates, T.O. | Deposit date: | 2007-08-09 | Release date: | 2008-03-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Atomic-level models of the bacterial carboxysome shell. Science, 319, 2008
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3UI7
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![BU of 3ui7 by Molmil](/molmil-images/mine/3ui7) | Discovery of orally active pyrazoloquinoline as a potent PDE10 inhibitor for the management of schizophrenia | Descriptor: | 6-methoxy-3,8-dimethyl-4-(morpholin-4-ylmethyl)-1H-pyrazolo[3,4-b]quinoline, MAGNESIUM ION, ZINC ION, ... | Authors: | Yang, S, Smotryski, J, Mcelroy, W, Ho, G, Tulshian, D, Greenlee, W.J, Hodgson, R, Xiao, L, Hruza, A. | Deposit date: | 2011-11-04 | Release date: | 2011-12-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia. Bioorg.Med.Chem.Lett., 22, 2012
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4OUF
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![BU of 4ouf by Molmil](/molmil-images/mine/4ouf) | Crystal Structure of CBP bromodomain | Descriptor: | 1,2-ETHANEDIOL, CREB-binding protein, DI(HYDROXYETHYL)ETHER | Authors: | Roy, S, Das, C, Tyler, J.K, Kutateladze, T.G. | Deposit date: | 2014-02-17 | Release date: | 2014-03-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation. Proc.Natl.Acad.Sci.USA, 111, 2014
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4OUK
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![BU of 4ouk by Molmil](/molmil-images/mine/4ouk) | Crystal structure of a C6-C4 SN3 inhibited ESTERASE B from LACTOBACILLUS RHAMNOSIS | Descriptor: | (2R)-2,3-bis(hexyloxy)propyl hydrogen (S)-pentylphosphonate, Esterase B | Authors: | Colbert, D.A, Bennett, M.D, Lun, D.J, Holland, R, Delabre, M.-L, Loo, T.S, Anderson, B.F, Norris, G.E. | Deposit date: | 2014-02-17 | Release date: | 2014-08-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a C6-C4 SN3 inhibited ESTERASE B from LACTOBACILLUS RHAMNOSIS TO BE PUBLISHED
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3UIZ
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4OZX
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![BU of 4ozx by Molmil](/molmil-images/mine/4ozx) | |
3ULL
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![BU of 3ull by Molmil](/molmil-images/mine/3ull) | |
4P09
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![BU of 4p09 by Molmil](/molmil-images/mine/4p09) | Crystal structure of HOIP PUB domain | Descriptor: | E3 ubiquitin-protein ligase RNF31 | Authors: | Akutsu, M, Schaeffer, V, Olma, M.H, Gomes, L.C, Kawasaki, M, Dikic, I. | Deposit date: | 2014-02-20 | Release date: | 2014-05-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Binding of OTULIN to the PUB domain of HOIP controls NF-kappa B signaling. Mol.Cell, 54, 2014
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4OV0
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![BU of 4ov0 by Molmil](/molmil-images/mine/4ov0) | Structure of Bacteriorhdopsin Transferred from Amphipol A8-35 to a Lipidic Mesophase | Descriptor: | Bacteriorhodopsin, RETINAL | Authors: | Polovinkin, V, Gushchin, I, Sintsov, M, Round, E, Balandin, T, Chervakov, P, Schevchenko, V, Utrobin, P, Popov, A, Borshchevskiy, V, Mishin, A, Kuklin, A, Willbold, D, Popot, J.L, Gordeliy, V. | Deposit date: | 2014-02-19 | Release date: | 2014-10-01 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | High-resolution structure of a membrane protein transferred from amphipol to a lipidic mesophase. J.Membr.Biol., 247, 2014
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3UKC
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![BU of 3ukc by Molmil](/molmil-images/mine/3ukc) | (S)-cEt-BNA decamer structure | Descriptor: | DNA (5'-D(*GP*CP*GP*TP*AP*(1TL)P*AP*CP*GP*C)-3') | Authors: | Pallan, P.S, Egli, M. | Deposit date: | 2011-11-09 | Release date: | 2012-06-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Structure and nuclease resistance of 2',4'-constrained 2'-O-methoxyethyl (cMOE) and 2'-O-ethyl (cEt) modified DNAs. Chem.Commun.(Camb.), 48, 2012
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4O6K
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![BU of 4o6k by Molmil](/molmil-images/mine/4o6k) | The crystal structure of zebrafish IL-22 | Descriptor: | Interleukin 22 | Authors: | Siupka, P, Hamming, O.J, Fretaud, M, Luftalla, G, Levraud, J.P, Hartmann, R. | Deposit date: | 2013-12-21 | Release date: | 2014-09-10 | Last modified: | 2018-05-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of zebrafish IL-22 reveals an evolutionary, conserved structure highly similar to that of human IL-22. Genes Immun., 15, 2014
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3UM5
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![BU of 3um5 by Molmil](/molmil-images/mine/3um5) | Double mutant (A16V+S108T) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS-T9/94) complexed with pyrimethamine, NADPH, and dUMP | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | Authors: | Vanichtanankul, J, Kamchonwongpaisan, S, Chitnumsub, P, Yuthavong, Y. | Deposit date: | 2011-11-12 | Release date: | 2012-07-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Combined Spatial Limitation around Residues 16 and 108 of Plasmodium falciparum Dihydrofolate Reductase Explains Resistance to Cycloguanil. Antimicrob.Agents Chemother., 56, 2012
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4OVD
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![BU of 4ovd by Molmil](/molmil-images/mine/4ovd) | Crystal structure of a putative peptidoglycan glycosyltransferase from Atopobium parvulum DSM 20469 | Descriptor: | CALCIUM ION, Peptidoglycan glycosyltransferase | Authors: | Filippova, E.V, Wawrzak, Z, Kiryukhina, O, Babnigg, G, Clancy, S, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-02-21 | Release date: | 2014-03-12 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a putative peptidoglycan glycosyltransferase from Atopobium parvulum DSM 20469 To be Published
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3UKI
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![BU of 3uki by Molmil](/molmil-images/mine/3uki) | Crystal structure of reduced OxyR from Porphyromonas gingivalis | Descriptor: | OxyR | Authors: | Svintradze, D.V, Wright, H.T, Collazo-Santiago, E.A, Lewis, J.P. | Deposit date: | 2011-11-09 | Release date: | 2013-07-31 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (4.15 Å) | Cite: | Structures of the Porphyromonas gingivalis OxyR regulatory domain explain differences in expression of the OxyR regulon in Escherichia coli and P. gingivalis. Acta Crystallogr.,Sect.D, 69, 2013
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2QSC
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![BU of 2qsc by Molmil](/molmil-images/mine/2qsc) | Crystal structure analysis of anti-HIV-1 V3-Fab F425-B4e8 in complex with a V3-peptide | Descriptor: | CHLORIDE ION, Envelope glycoprotein gp120, Fab F425-B4e8, ... | Authors: | Bell, C.H, Schiefner, A, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2007-07-30 | Release date: | 2008-01-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization. J.Mol.Biol., 375, 2008
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3UKX
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![BU of 3ukx by Molmil](/molmil-images/mine/3ukx) | Mouse importin alpha: Bimax2 peptide complex | Descriptor: | Bimax2 peptide, Importin subunit alpha-2 | Authors: | Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. | Deposit date: | 2011-11-10 | Release date: | 2012-10-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
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