3UKC

(S)-cEt-BNA decamer structure

Summary for 3UKC

Related3UKB 3UKE
DescriptorDNA (5'-D(*GP*CP*GP*TP*AP*(1TL)P*AP*CP*GP*C)-3') (2 entities in total)
Functional Keywordsa-form dna, bicyclic nucleic acid, bna, dna, cet-bna, antisense oligonucleotides
Total number of polymer chains2
Total molecular weight6146.03
Authors
Pallan, P.S.,Egli, M. (deposition date: 2011-11-09, release date: 2012-06-20, Last modification date: 2012-08-08)
Primary citation
Pallan, P.S.,Allerson, C.R.,Berdeja, A.,Seth, P.P.,Swayze, E.E.,Prakash, T.P.,Egli, M.
Structure and nuclease resistance of 2',4'-constrained 2'-O-methoxyethyl (cMOE) and 2'-O-ethyl (cEt) modified DNAs.
Chem.Commun.(Camb.), 48:8195-8197, 2012
PubMed: 22614180 (PDB entries with the same primary citation)
DOI: 10.1039/c2cc32286b
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.54 Å)
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Structure validation

RfreeClashscoreRSRZ outliers0.21300MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3ukc
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Molmil generated image of 3ukc
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Molmil generated image of 3ukc
rotated about y axis by 90°