PDB: 591 件ウェブページステータス検索Chemie searchBIRD

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2LNX	Solution structure of Vav2 SH2 domain 分子名称: Guanine nucleotide exchange factor VAV2 著者 Wu, B, Zhang, J, Wu, J, Shi, Y. 登録日 2012-01-05 公開日 2012-11-21 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Identification and structural basis for a novel interaction between Vav2 and Arap3. J.Struct.Biol., 180, 2012
2LCT	Solution structure of the Vav1 SH2 domain complexed with a Syk-derived doubly phosphorylated peptide 分子名称: Proto-oncogene vav, Tyrosine-protein kinase SYK 著者 Chen, C, Gorenstein, N, Post, C. 登録日 2011-05-09 公開日 2011-06-01 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav. Mol.Cell.Biol., 31, 2011
2MC1	Solution structure of the Vav1 SH2 domain complexed with a Syk-derived singly phosphorylated peptide 分子名称: Proto-oncogene vav, Tyrosine-protein kinase SYK 著者 Chen, C, Piraner, D, Gorenstein, N.M, Geahlen, R.L, Post, C.B. 登録日 2013-08-13 公開日 2013-08-28 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Differential recognition of syk-binding sites by each of the two phosphotyrosine-binding pockets of the Vav SH2 domain. Biopolymers, 99, 2013
2MK2	Solution NMR structure of N-terminal domain (SH2 domain) of human Inositol polyphosphate phosphatase-like protein 1 (INPPL1) (fragment 20-117), Northeast Structural Genomics Consortium Target HR9134A 分子名称: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 著者 Yang, Y, Ramelot, T.A, Janjua, H, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) 登録日 2014-01-23 公開日 2014-03-05 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution NMR structure of N-terminal domain (SH2 domain) of human Inositol polyphosphate phosphatase-like protein 1 (INPPL1) (fragment 20-117), Northeast Structural Genomics Consortium Target HR9134A. To be Published
2MQI	human Fyn SH2 free state 分子名称: Tyrosine-protein kinase Fyn 著者 Huculeci, R, Buts, L, Lenaerts, T, VanNuland, N. 登録日 2014-06-20 公開日 2015-07-29 最終更新日 2016-12-14 実験手法 SOLUTION NMR 主引用文献 Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity. Structure, 24, 2016
2MRJ	Structure of Fyn protein SH2 bound 分子名称: Tyrosine-protein kinase Fyn 著者 Huculeci, R, Buts, L, Lenaerts, T, Van Nuland, N. 登録日 2014-07-09 公開日 2015-07-15 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity. Structure, 24, 2016
2MRK	Fyn SH2 domain in complex with the natural inhibitory phosphotyrosine peptide 分子名称: C-terminal Tyrosine-protein kinase Fyn, Tyrosine-protein kinase Fyn 著者 Huculeci, R, Buts, L, Lenaerts, A.J, van Nuland, N. 登録日 2014-07-09 公開日 2015-07-15 最終更新日 2016-12-14 実験手法 SOLUTION NMR 主引用文献 Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity. Structure, 24, 2016
2PNB	STRUCTURE OF AN SH2 DOMAIN OF THE P85 ALPHA SUBUNIT OF PHOSPHATIDYLINOSITOL-3-OH KINASE 分子名称: PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT N-TERMINAL SH2 DOMAIN 著者 Booker, G.W, Breeze, A.L, Downing, A.K, Panayotou, G, Gout, I, Waterfield, M.D, Campbell, I.D. 登録日 1992-06-30 公開日 1994-01-31 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Structure of an SH2 domain of the p85 alpha subunit of phosphatidylinositol-3-OH kinase. Nature, 358, 1992
2PLE	NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE 分子名称: PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF 著者 Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D. 登録日 1994-08-19 公開日 1995-01-26 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide. Cell(Cambridge,Mass.), 77, 1994
2PLD	NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE 分子名称: PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF 著者 Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D. 登録日 1994-08-19 公開日 1995-01-26 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide. Cell(Cambridge,Mass.), 77, 1994
2PNA	STRUCTURE OF AN SH2 DOMAIN OF THE P85 ALPHA SUBUNIT OF PHOSPHATIDYLINOSITOL-3-OH KINASE 分子名称: PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT N-TERMINAL SH2 DOMAIN 著者 Booker, G.W, Breeze, A.L, Downing, A.K, Panayotou, G, Gout, I, Waterfield, M.D, Campbell, I.D. 登録日 1992-06-30 公開日 1994-01-31 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Structure of an SH2 domain of the p85 alpha subunit of phosphatidylinositol-3-OH kinase. Nature, 358, 1992
2QMS	Crystal structure of a signaling molecule 分子名称: Growth factor receptor-bound protein 7, SULFATE ION 著者 Porter, C.J, Wilce, M.C, Wilce, J.A. 登録日 2007-07-16 公開日 2008-07-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation. Bmc Struct.Biol., 7, 2007
2RMX	Solution structure of the SHP-1 C-terminal SH2 domain complexed with a tyrosine-phosphorylated peptide from NKG2A 分子名称: NKG2-A/NKG2-B type II integral membrane protein, Tyrosine-protein phosphatase non-receptor type 6 著者 Kasai, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-11-30 公開日 2008-12-02 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Structural basis for the recognition of the two NKG2A immunoreceptor tyrosine-based inhibitory motifs (ITIMs) by the C-terminal SH2 domain of protein tyrosine phosphatase SHP-1 To be Published
2RSY	Solution structure of the SH2 domain of Csk in complex with a phosphopeptide from Cbp 分子名称: Phosphoprotein associated with glycosphingolipid-enriched microdomains 1, Tyrosine-protein kinase CSK 著者 Tanaka, H, Akagi, K, Oneyama, C, Tanaka, M, Sasaki, Y, Kanou, T, Lee, Y, Yokogawa, D, Debenecker, M, Nakagawa, A, Okada, M, Ikegami, T. 登録日 2012-09-10 公開日 2013-04-10 最終更新日 2019-12-25 実験手法 SOLUTION NMR 主引用文献 Identification of a new interaction mode between the Src homology 2 domain of C-terminal Src kinase (Csk) and Csk-binding protein/phosphoprotein associated with glycosphingolipid microdomains. J.Biol.Chem., 288, 2013
2ROR	Solution structure of the VAV1 SH2 domain complexed with a tyrosine-phosphorylated peptide from SLP76 分子名称: 15-meric peptide from Lymphocyte cytosolic protein 2, Proto-oncogene vav 著者 Tanaka, M, Kasai, T, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2008-04-08 公開日 2009-04-21 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of the VAV1 SH2 domain complexed with a tyrosine-phosphorylated peptide from SLP76 To be Published
2RVF	Solution NMR structure of Monosiga brevicollis CRK/CRKL homolog (crka1) SH2 domain 分子名称: Predicted protein 著者 Kasai, T, Pawlak, J, Imamoto, A, Kigawa, T. 登録日 2015-09-24 公開日 2016-09-21 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 A pre-metazoan origin of the CRK gene family and co-opted signaling network Sci Rep, 6, 2016
2EYV	SH2 domain of CT10-Regulated Kinase 分子名称: v-crk sarcoma virus CT10 oncogene homolog isoform a 著者 Kobashigawa, Y, Tanaka, S, Inagaki, F. 登録日 2005-11-10 公開日 2006-11-10 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Nat.Struct.Mol.Biol., 14, 2007
2ETZ	The NMR minimized average structure of the Itk SH2 domain bound to a phosphopeptide 分子名称: Lymphocyte cytosolic protein 2 phosphopeptide fragment, Tyrosine-protein kinase ITK/TSK 著者 Sundd, M, Pletneva, E.V, Fulton, D.B, Andreotti, A.H. 登録日 2005-10-27 公開日 2006-02-07 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Molecular Details of Itk Activation by Prolyl Isomerization and Phospholigand Binding: The NMR Structure of the Itk SH2 Domain Bound to a Phosphopeptide. J.Mol.Biol., 357, 2006
1HCT	NMR STRUCTURE OF THE HUMAN SRC SH2 DOMAIN COMPLEX 分子名称: ACETYL-PYEEIE-OH, HUMAN SRC 著者 Gampe Junior, R.T, Xu, R.X. 登録日 1994-09-02 公開日 1995-09-15 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Solution structure of the human pp60c-src SH2 domain complexed with a phosphorylated tyrosine pentapeptide. Biochemistry, 34, 1995
1HCS	NMR STRUCTURE OF THE HUMAN SRC SH2 DOMAIN COMPLEX 分子名称: ACETYL-PYEEIE-OH, HUMAN SRC 著者 Gampe Junior, R.T, Xu, R.X. 登録日 1994-09-02 公開日 1995-09-15 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Solution structure of the human pp60c-src SH2 domain complexed with a phosphorylated tyrosine pentapeptide. Biochemistry, 34, 1995
1H9O	PHOSPHATIDYLINOSITOL 3-KINASE, P85-ALPHA SUBUNIT: C-TERMINAL SH2 DOMAIN COMPLEXED WITH A TYR751 PHOSPHOPEPTIDE FROM THE PDGF RECEPTOR, CRYSTAL STRUCTURE AT 1.79 A 分子名称: BETA-PLATELET-DERIVED GROWTH FACTOR RECEPTOR, PHOSPHATIDYLINOSITOL 3-KINASE 著者 Pauptit, R.A, Rowsell, S, Breeze, A.L, Murshudov, G.N, Dennis, C.A, Derbyshire, D.J, Weston, S.A. 登録日 2001-03-14 公開日 2001-03-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 NMR Trial Models: Experiences with the Colicin Immunity Protein Im7 and the P85Alpha C-Terminal Sh2-Peptide Complex Acta Crystallogr.,Sect.D, 57, 2001
2EU0	The NMR ensemble structure of the Itk SH2 domain bound to a phosphopeptide 分子名称: Lymphocyte cytosolic protein 2 phosphopeptide fragment, Tyrosine-protein kinase ITK/TSK 著者 Sundd, M, Pletneva, E.V, Fulton, D.B, Andreotti, A.H. 登録日 2005-10-27 公開日 2006-02-07 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Molecular Details of Itk Activation by Prolyl Isomerization and Phospholigand Binding: The NMR Structure of the Itk SH2 Domain Bound to a Phosphopeptide. J.Mol.Biol., 357, 2006
2FCI	Structural basis for the requirement of two phosphotyrosines in signaling mediated by Syk tyrosine kinase 分子名称: C-termainl SH2 domain from phospholipase C-gamma-1 comprising residues 663-759, Doubly phosphorylated peptide derived from Syk kinase comprising residues 338-350 著者 Groesch, T.D, Zhou, F, Mattila, S, Geahlen, R.L, Post, C.B. 登録日 2005-12-12 公開日 2006-01-31 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Structural basis for the requirement of two phosphotyrosine residues in signaling mediated by syk tyrosine kinase J.Mol.Biol., 356, 2006
1I3Z	MURINE EAT2 SH2 DOMAIN IN COMPLEX WITH SLAM PHOSPHOPEPTIDE 分子名称: EWS/FLI1 ACTIVATED TRANSCRIPT 2, SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE 著者 Lu, J, Poy, F, Morra, M, Terhorst, C, Eck, M.J. 登録日 2001-02-19 公開日 2003-04-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells. Eur.J.Biochem., 20, 2001
2GE9	Solution Structures of the SH2 domain of Bruton's Tyrosine Kinase 分子名称: Tyrosine-protein kinase BTK 著者 Cheng, J.-W, Huang, K.-C. 登録日 2006-03-18 公開日 2006-10-24 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure and phosphopeptide binding of the SH2 domain from the human Bruton's tyrosine kinase J.Biomol.Nmr, 36, 2006

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