1H9O

PHOSPHATIDYLINOSITOL 3-KINASE, P85-ALPHA SUBUNIT: C-TERMINAL SH2 DOMAIN COMPLEXED WITH A TYR751 PHOSPHOPEPTIDE FROM THE PDGF RECEPTOR, CRYSTAL STRUCTURE AT 1.79 A

Summary for 1H9O

Related1A0N 1AZG 1PBW 1PHT 1PIC 1PKS 1PKT
DescriptorPHOSPHATIDYLINOSITOL 3-KINASE, BETA-PLATELET-DERIVED GROWTH FACTOR RECEPTOR (3 entities in total)
Functional Keywordstransferase/receptor, complex (phosphotransferase-receptor), phosphotransferase, sh2 domain, signal transduction, phosphoinositide 3-kinase, transferase-receptor complex
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCell membrane; Single-pass type I membrane protein P09619
Total number of polymer chains2
Total molecular weight13313.86
Authors
Pauptit, R.A.,Rowsell, S.,Breeze, A.L.,Murshudov, G.N.,Dennis, C.A.,Derbyshire, D.J.,Weston, S.A. (deposition date: 2001-03-14, release date: 2001-03-19, Last modification date: 2017-06-28)
Primary citation
Pauptit, R.A.,Dennis, C.A.,Derbyshire, D.J.,Breeze, A.L.,Weston, S.A.,Rowsell, S.,Murshudov, G.N.
NMR Trial Models: Experiences with the Colicin Immunity Protein Im7 and the P85Alpha C-Terminal Sh2-Peptide Complex
Acta Crystallogr.,Sect.D, 57:1397-, 2001
PubMed: 11567151 (PDB entries with the same primary citation)
DOI: 10.1107/S0907444901012434
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.79 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2281004.1%7.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1h9o
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Molmil generated image of 1h9o
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Molmil generated image of 1h9o
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