1H9O

PHOSPHATIDYLINOSITOL 3-KINASE, P85-ALPHA SUBUNIT: C-TERMINAL SH2 DOMAIN COMPLEXED WITH A TYR751 PHOSPHOPEPTIDE FROM THE PDGF RECEPTOR, CRYSTAL STRUCTURE AT 1.79 A

Summary for 1H9O

Entry DOI	10.2210/pdb1h9o/pdb
Related	1A0N 1AZG 1PBW 1PHT 1PIC 1PKS 1PKT
Descriptor	PHOSPHATIDYLINOSITOL 3-KINASE, BETA-PLATELET-DERIVED GROWTH FACTOR RECEPTOR (3 entities in total)
Functional Keywords	transferase/receptor, complex (phosphotransferase-receptor), phosphotransferase, sh2 domain, signal transduction, phosphoinositide 3-kinase, transferase-receptor complex
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Cell membrane; Single-pass type I membrane protein: P09619
Total number of polymer chains	2
Total formula weight	13313.86
Authors	Pauptit, R.A.,Rowsell, S.,Breeze, A.L.,Murshudov, G.N.,Dennis, C.A.,Derbyshire, D.J.,Weston, S.A. (deposition date: 2001-03-14, release date: 2001-03-19, Last modification date: 2023-12-13)
Primary citation	Pauptit, R.A.,Dennis, C.A.,Derbyshire, D.J.,Breeze, A.L.,Weston, S.A.,Rowsell, S.,Murshudov, G.N. NMR Trial Models: Experiences with the Colicin Immunity Protein Im7 and the P85Alpha C-Terminal Sh2-Peptide Complex Acta Crystallogr.,Sect.D, 57:1397-, 2001 Cited by PubMed: 11567151 DOI: 10.1107/S0907444901012434 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.79 Å)

Structure validation