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1PIC

PHOSPHATIDYLINOSITOL 3-KINASE, P85-ALPHA SUBUNIT: C-TERMINAL SH2 DOMAIN COMPLEXED WITH A TYR751 PHOSPHOPEPTIDE FROM THE PDGF RECEPTOR, NMR, MINIMIZED MEAN STRUCTURE

Summary for 1PIC
Entry DOI10.2210/pdb1pic/pdb
DescriptorPHOSPHATIDYLINOSITOL 3-KINASE, BETA-PLATELET-DERIVED GROWTH FACTOR RECEPTOR (2 entities in total)
Functional Keywordsphosphotransferase, sh2 domain, signal transduction, phosphoinositide 3-kinase, complex (phosphotransferase-receptor), complex (phosphotransferase-receptor) complex, complex (phosphotransferase/receptor)
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight13339.90
Authors
Breeze, A.L.,Kara, B.V.,Barratt, D.G.,Anderson, M.,Smith, J.C.,Luke, R.W.,Best, J.R.,Cartlidge, S.A. (deposition date: 1997-06-23, release date: 1997-09-17, Last modification date: 2022-02-23)
Primary citationBreeze, A.L.,Kara, B.V.,Barratt, D.G.,Anderson, M.,Smith, J.C.,Luke, R.W.,Best, J.R.,Cartlidge, S.A.
Structure of a specific peptide complex of the carboxy-terminal SH2 domain from the p85 alpha subunit of phosphatidylinositol 3-kinase.
EMBO J., 15:3579-3589, 1996
Cited by
PubMed: 8670861
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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