PDB: 92212 resultsInfo pagesStatus searchChemie searchBIRD

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4URZ	The crystal structure of H-Ras and SOS in complex with ligands Descriptor: 1-[(4-aminophenyl)sulfonyl]piperidin-2-one, GTPASE HRAS, SON OF SEVENLESS HOMOLOG 1 Authors: Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G. Deposit date: 2014-07-02 Release date: 2015-03-04 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation. J.Med.Chem., 58, 2015
4URX	The crystal structure of H-Ras and SOS in complex with ligands Descriptor: 1-(4-bromobenzyl)pyrrolidine, 6-bromo-1H-indole, FORMIC ACID, ... Authors: Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G. Deposit date: 2014-07-02 Release date: 2015-03-04 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation. J.Med.Chem., 58, 2015
4URV	The crystal structure of H-Ras and SOS in complex with ligands Descriptor: 4-(4-BROMOPHENYL)PIPERIDIN-4-OL, FORMIC ACID, GTPASE HRAS, ... Authors: Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G. Deposit date: 2014-07-02 Release date: 2015-03-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.58 Å) Cite: Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation. J.Med.Chem., 58, 2015
7OSN	IRED361 from Micromonospora sp. in complex with NADP+ Descriptor: 6-phosphogluconate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Gilio, A.K, Harawa, V, Turner, N, Grogan, G.J. Deposit date: 2021-06-09 Release date: 2022-06-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Synthesis of Stereoenriched Piperidines via Chemo-Enzymatic Dearomatization of Activated Pyridines. J.Am.Chem.Soc., 144, 2022
5X33	Leukotriene B4 receptor BLT1 in complex with BIIL260 Descriptor: 4-[[3-[[4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy]methyl]phenyl]methoxy]benzenecarboximidamide, LTB4 receptor,Lysozyme,LTB4 receptor Authors: Hori, T, Hirata, K, Yamashita, K, Kawano, Y, Yamamoto, M, Yokoyama, S. Deposit date: 2017-02-03 Release date: 2018-01-03 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Na+-mimicking ligands stabilize the inactive state of leukotriene B4receptor BLT1. Nat. Chem. Biol., 14, 2018
4XLS	Crystal structure of T. aquaticus transcription initiation complex with CarD containing upstream fork promoter. Descriptor: CarD-like transcriptional regulator, DNA (30-MER), DNA (5'-D(P*GP*CP*AP*CP*AP*AP*TP*TP*TP*AP*AP*CP*AP*CP*TP*TP*TP*TP*GP*TP*CP*AP*AP*G)-3'), ... Authors: Bae, B, Darst, S.A. Deposit date: 2015-01-13 Release date: 2015-09-23 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (4.01 Å) Cite: CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex. Elife, 4, 2015
4XLR	Crystal structure of T.aquaticus transcription initiation complex with CarD containing bubble promoter and RNA Descriptor: CarD-like transcriptional regulator, DNA (48-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Bae, B, Darst, S.A. Deposit date: 2015-01-13 Release date: 2015-09-23 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (4.3 Å) Cite: CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex. Elife, 4, 2015
5LT5	Carboxysome shell protein CcmP from Synechococcus elongatus PCC 7942 Descriptor: CHLORIDE ION, CcmP, GLYCEROL Authors: Larsson, A.M, Hasse, D, Valegard, K, Andersson, I. Deposit date: 2016-09-06 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Crystal structures of beta-carboxysome shell protein CcmP: ligand binding correlates with the closed or open central pore. J. Exp. Bot., 68, 2017
4XLN	Crystal structure of T. aquaticus transcription initiation complex containing bubble promoter and RNA Descriptor: DNA (48-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Bae, B, Darst, S.A. Deposit date: 2015-01-13 Release date: 2015-09-23 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (4 Å) Cite: Structure of a bacterial RNA polymerase holoenzyme open promoter complex. Elife, 4, 2015
5LEV	Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant) Descriptor: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, UNKNOWN LIGAND Authors: Pike, A.C.W, Dong, Y.Y, Chu, A, Tessitore, A, Goubin, S, Dong, L, Mukhopadhyay, S, Mahajan, P, Chalk, R, Berridge, G, Wang, D, Kupinska, K, Belaya, K, Beeson, D, Burgess-Brown, N, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) Deposit date: 2016-06-30 Release date: 2016-12-28 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design. Cell, 175, 2018
6AOW	Crystal structure of lectin domain of F9 pilus adhesin FmlH from E. coli UTI89 Descriptor: F9 pilus adhesin FmlH, SULFATE ION Authors: Kalas, V, Hultgren, S.J. Deposit date: 2017-08-16 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection. Proc.Natl.Acad.Sci.USA, 115, 2018
6OY7	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 7 min Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-14 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.04 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
4XGK	Crystal structure of UDP-galactopyranose mutase from Corynebacterium diphtheriae in complex with 2-[4-(4-chlorophenyl)-7-(2-thienyl)-2-thia-5,6,8,9-tetrazabicyclo[4.3.0]nona-4,7,9-trien-3-yl]acetic Descriptor: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, UDP-galactopyranose mutase, ... Authors: Wangkanont, K, Heroux, A, Forest, K.T, Kiessling, L.L. Deposit date: 2014-12-31 Release date: 2015-08-12 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.652 Å) Cite: Virtual Screening for UDP-Galactopyranose Mutase Ligands Identifies a New Class of Antimycobacterial Agents. Acs Chem.Biol., 10, 2015
4XLQ	Crystal structure of T.aquaticus transcription initiation complex containing upstream fork (-11 base-paired) promoter Descriptor: DNA (26-MER), DNA (30-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Bae, B, Darst, S.A. Deposit date: 2015-01-13 Release date: 2015-09-23 Last modified: 2019-12-25 Method: X-RAY DIFFRACTION (4.6 Å) Cite: Structure of a bacterial RNA polymerase holoenzyme open promoter complex. Elife, 4, 2015
6M2Z	Crystal structure of a formolase, BFD variant M3 from Pseudomonas putida Descriptor: Benzoylformate decarboxylase, MAGNESIUM ION, THIAMINE DIPHOSPHATE Authors: Wei, H.L, Liu, W.D, Li, T.Z, Zhu, L.L. Deposit date: 2020-03-02 Release date: 2021-03-03 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Totally atom-economical synthesis of lactic acid from formaldehyde: combined bio-carboligation and chemo-rearrangement without the isolation of intermediate. Green Chem, 22, 2020
6M2Y	Crystal structure of a formolase, BFD variant M6 from Pseudomonas putida Descriptor: Benzoylformate decarboxylase, MAGNESIUM ION, THIAMINE DIPHOSPHATE Authors: Wei, H.L, Liu, W.D, Li, T.Z, Zhu, L.L. Deposit date: 2020-03-02 Release date: 2021-03-03 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Totally atom-economical synthesis of lactic acid from formaldehyde: combined bio-carboligation and chemo-rearrangement without the isolation of intermediate. Green Chem, 22, 2020
6OVY	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1C Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*CP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-08 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.999 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
5LSR	Carboxysome shell protein CcmP from Synechococcus elongatus PCC 7942 Descriptor: CcmP, THIOCYANATE ION Authors: Larsson, A.M, Hasse, D, Valegard, K, Andersson, I. Deposit date: 2016-09-05 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structures of beta-carboxysome shell protein CcmP: ligand binding correlates with the closed or open central pore. J. Exp. Bot., 68, 2017
1CYB	NMR STUDIES OF (U-13C)CYCLOSPORIN A BOUND TO CYCLOPHILIN: BOUND CONFORMATION AND PORTIONS OF CYCLOSPORIN INVOLVED IN BINDING Descriptor: CYCLOSPORIN A Authors: Fesik, S.W. Deposit date: 1992-02-24 Release date: 1994-01-31 Last modified: 2024-06-05 Method: SOLUTION NMR Cite: NMR Studies of [U-13C]Cyclosporin a Bound to Cyclophilin: Bound Conformation and Portions of Cyclosporin Involved in Binding. Biochemistry, 30, 1991
1WJX	Crystal sturucture of TT0801 from Thermus thermophilus Descriptor: POTASSIUM ION, SsrA-binding protein Authors: Bessho, Y, Shibata, R, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2004-05-29 Release date: 2004-11-29 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural basis for functional mimicry of long-variable-arm tRNA by transfer-messenger RNA. Proc.Natl.Acad.Sci.Usa, 104, 2007
2XF2	PVC-AT Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-AMINO-1,2,4-TRIAZOLE, CALCIUM ION, ... Authors: Borovik, A, Melik-Adamyan, W.R. Deposit date: 2010-05-20 Release date: 2010-06-16 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: X-Ray Investigation of Penicillium Vitale Catalase Inhibited by Aminotriazole Crystallography Reports, 56, 2011
6OW3	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1T Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*GP*AP*TP*CP*TP*GP*AP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*TP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-09 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.766 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6OY6	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 5 min Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*GP*AP*TP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-14 Release date: 2019-06-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.096 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6OY5	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 3 min Descriptor: DNA (5'-D(*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*CP*TP*CP*TP*GP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*CP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*AP*T)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-14 Release date: 2019-06-05 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
7Q39	Ribonucleotide Reductase R2_genomic protein from Aquifex aeolicus Descriptor: FE (III) ION, Ribonucleoside-diphosphate reductase subunit beta Authors: Scaletti, E, Rehling, D, Stenmark, P. Deposit date: 2021-10-27 Release date: 2022-04-20 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus. Biochemistry, 61, 2022

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