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4XLR

Crystal structure of T.aquaticus transcription initiation complex with CarD containing bubble promoter and RNA

Summary for 4XLR
Entry DOI10.2210/pdb4xlr/pdb
Related4XAX 4XLN 4XLP 4XLQ 4XLS
DescriptorDNA-directed RNA polymerase subunit alpha, ZINC ION, MAGNESIUM ION, ... (11 entities in total)
Functional Keywordsprotein-dna complex, bacterial transcription initiation complex, transcription-dna complex, transcription/dna
Biological sourceThermus aquaticus
More
Cellular locationCytoplasm : Q9EZJ8
Total number of polymer chains20
Total formula weight933417.03
Authors
Bae, B.,Darst, S.A. (deposition date: 2015-01-13, release date: 2015-09-23, Last modification date: 2017-11-22)
Primary citationBae, B.,Chen, J.,Davis, E.,Leon, K.,Darst, S.A.,Campbell, E.A.
CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex.
Elife, 4:-, 2015
Cited by
PubMed: 26349034
DOI: 10.7554/eLife.08505
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (4.3 Å)
Structure validation

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