4XLR

Crystal structure of T.aquaticus transcription initiation complex with CarD containing bubble promoter and RNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, G, H (A, B, G, H)	DNA-directed RNA polymerase subunit alpha	polymer	314	34830.9	4	UniProt (Q9KWU8)	Thermus aquaticus	RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha
2	C, I (C, I)	DNA-directed RNA polymerase subunit beta	polymer	1119	124930.0	2	UniProt (Q9KWU7)	Thermus aquaticus	RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
3	D, J (D, J)	DNA-directed RNA polymerase subunit beta'	polymer	1524	171187.5	2	UniProt (Q9KWU6)	Thermus aquaticus	RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta'
4	E, K (E, K)	DNA-directed RNA polymerase subunit omega	polymer	99	11642.4	2	UniProt (Q9EVV4)	Thermus aquaticus	RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega
5	F, L (F, L)	RNA polymerase sigma factor SigA	polymer	347	39864.7	2	UniProt (Q9EZJ8)	Thermus aquaticus
6	M, N (M, N)	CarD-like transcriptional regulator	polymer	164	18316.0	2	UniProt (H9ZP94)	Thermus thermophilus JL-18
7	O, R (O, R)	DNA (48-MER)	polymer	48	14878.6	2		synthetic construct
8	P, S (P, S)	DNA (48-MER)	polymer	48	14831.5	2		synthetic construct
9	Q, T (Q, T)	RNA (5'-R(P*UP*CP*GP*A)-3')	polymer	4	1240.8	2		synthetic construct
10	U, V, X, Y (D, J)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
11	W, Z (D, J)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)

Contents of the asymmetric unit

Polymers	Number of chains	20
	Total formula weight	933106.8
Non-Polymers*	Number of molecules	6
	Total formula weight	310.2
All*	Total formula weight	933417.0

*Water molecules are not included.