4XLR
Crystal structure of T.aquaticus transcription initiation complex with CarD containing bubble promoter and RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, G, H | DNA-directed RNA polymerase subunit alpha | polymer | 314 | 34830.9 | 4 | UniProt (Q9KWU8) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) In PDB | Thermus aquaticus | RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha |
| 2 | C, I | DNA-directed RNA polymerase subunit beta | polymer | 1119 | 124930.0 | 2 | UniProt (Q9KWU7) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) In PDB | Thermus aquaticus | RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta |
| 3 | D, J | DNA-directed RNA polymerase subunit beta' | polymer | 1524 | 171187.5 | 2 | UniProt (Q9KWU6) Pfam (PF04997) Pfam (PF21668) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB | Thermus aquaticus | RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta' |
| 4 | E, K | DNA-directed RNA polymerase subunit omega | polymer | 99 | 11642.4 | 2 | UniProt (Q9EVV4) Pfam (PF01192) In PDB | Thermus aquaticus | RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega |
| 5 | F, L | RNA polymerase sigma factor SigA | polymer | 347 | 39864.7 | 2 | UniProt (Q9EZJ8) Pfam (PF00140) Pfam (PF04542) Pfam (PF04539) Pfam (PF04545) In PDB | Thermus aquaticus | |
| 6 | M, N | CarD-like transcriptional regulator | polymer | 164 | 18316.0 | 2 | UniProt (H9ZP94) Pfam (PF02559) Pfam (PF21095) In PDB | Thermus thermophilus JL-18 | |
| 7 | O, R | DNA (48-MER) | polymer | 48 | 14878.6 | 2 | synthetic construct | ||
| 8 | P, S | DNA (48-MER) | polymer | 48 | 14831.5 | 2 | synthetic construct | ||
| 9 | Q, T | RNA (5'-R(P*UP*CP*GP*A)-3') | polymer | 4 | 1240.8 | 2 | synthetic construct | ||
| 10 | D, J | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 11 | D, J | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 933106.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 310.2 | |
| All* | Total formula weight | 933417.0 |
