Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

4XLR

Crystal structure of T.aquaticus transcription initiation complex with CarD containing bubble promoter and RNA

Functional Information from GO Data
ChainGOidnamespacecontents
A0000428cellular_componentDNA-directed RNA polymerase complex
A0003677molecular_functionDNA binding
A0003899molecular_functionDNA-directed RNA polymerase activity
A0005737cellular_componentcytoplasm
A0006351biological_processDNA-templated transcription
A0016740molecular_functiontransferase activity
A0016779molecular_functionnucleotidyltransferase activity
A0034062molecular_function5'-3' RNA polymerase activity
A0046983molecular_functionprotein dimerization activity
B0000428cellular_componentDNA-directed RNA polymerase complex
B0003677molecular_functionDNA binding
B0003899molecular_functionDNA-directed RNA polymerase activity
B0005737cellular_componentcytoplasm
B0006351biological_processDNA-templated transcription
B0016740molecular_functiontransferase activity
B0016779molecular_functionnucleotidyltransferase activity
B0034062molecular_function5'-3' RNA polymerase activity
B0046983molecular_functionprotein dimerization activity
C0000428cellular_componentDNA-directed RNA polymerase complex
C0003677molecular_functionDNA binding
C0003899molecular_functionDNA-directed RNA polymerase activity
C0006351biological_processDNA-templated transcription
C0016740molecular_functiontransferase activity
C0016779molecular_functionnucleotidyltransferase activity
C0032549molecular_functionribonucleoside binding
C0034062molecular_function5'-3' RNA polymerase activity
D0000287molecular_functionmagnesium ion binding
D0000428cellular_componentDNA-directed RNA polymerase complex
D0003677molecular_functionDNA binding
D0003899molecular_functionDNA-directed RNA polymerase activity
D0006351biological_processDNA-templated transcription
D0008270molecular_functionzinc ion binding
D0016740molecular_functiontransferase activity
D0016779molecular_functionnucleotidyltransferase activity
D0034062molecular_function5'-3' RNA polymerase activity
D0046872molecular_functionmetal ion binding
E0000428cellular_componentDNA-directed RNA polymerase complex
E0003677molecular_functionDNA binding
E0003899molecular_functionDNA-directed RNA polymerase activity
E0006351biological_processDNA-templated transcription
E0016740molecular_functiontransferase activity
E0016779molecular_functionnucleotidyltransferase activity
E0034062molecular_function5'-3' RNA polymerase activity
F0003677molecular_functionDNA binding
F0003700molecular_functionDNA-binding transcription factor activity
F0006352biological_processDNA-templated transcription initiation
F0006355biological_processregulation of DNA-templated transcription
F0016987molecular_functionsigma factor activity
G0000428cellular_componentDNA-directed RNA polymerase complex
G0003677molecular_functionDNA binding
G0003899molecular_functionDNA-directed RNA polymerase activity
G0005737cellular_componentcytoplasm
G0006351biological_processDNA-templated transcription
G0016740molecular_functiontransferase activity
G0016779molecular_functionnucleotidyltransferase activity
G0034062molecular_function5'-3' RNA polymerase activity
G0046983molecular_functionprotein dimerization activity
H0000428cellular_componentDNA-directed RNA polymerase complex
H0003677molecular_functionDNA binding
H0003899molecular_functionDNA-directed RNA polymerase activity
H0005737cellular_componentcytoplasm
H0006351biological_processDNA-templated transcription
H0016740molecular_functiontransferase activity
H0016779molecular_functionnucleotidyltransferase activity
H0034062molecular_function5'-3' RNA polymerase activity
H0046983molecular_functionprotein dimerization activity
I0000428cellular_componentDNA-directed RNA polymerase complex
I0003677molecular_functionDNA binding
I0003899molecular_functionDNA-directed RNA polymerase activity
I0006351biological_processDNA-templated transcription
I0016740molecular_functiontransferase activity
I0016779molecular_functionnucleotidyltransferase activity
I0032549molecular_functionribonucleoside binding
I0034062molecular_function5'-3' RNA polymerase activity
J0000287molecular_functionmagnesium ion binding
J0000428cellular_componentDNA-directed RNA polymerase complex
J0003677molecular_functionDNA binding
J0003899molecular_functionDNA-directed RNA polymerase activity
J0006351biological_processDNA-templated transcription
J0008270molecular_functionzinc ion binding
J0016740molecular_functiontransferase activity
J0016779molecular_functionnucleotidyltransferase activity
J0034062molecular_function5'-3' RNA polymerase activity
J0046872molecular_functionmetal ion binding
K0000428cellular_componentDNA-directed RNA polymerase complex
K0003677molecular_functionDNA binding
K0003899molecular_functionDNA-directed RNA polymerase activity
K0006351biological_processDNA-templated transcription
K0016740molecular_functiontransferase activity
K0016779molecular_functionnucleotidyltransferase activity
K0034062molecular_function5'-3' RNA polymerase activity
L0003677molecular_functionDNA binding
L0003700molecular_functionDNA-binding transcription factor activity
L0006352biological_processDNA-templated transcription initiation
L0006355biological_processregulation of DNA-templated transcription
L0016987molecular_functionsigma factor activity
M0009303biological_processrRNA transcription
N0009303biological_processrRNA transcription
Functional Information from PDB Data
site_idAC1
Number of Residues6
Detailsbinding site for residue ZN D 2001
ChainResidue
DCYS1112
DARG1189
DCYS1194
DTHR1196
DCYS1201
DCYS1204
site_idAC2
Number of Residues4
Detailsbinding site for residue ZN D 2002
ChainResidue
DCYS76
DCYS58
DCYS60
DCYS73
site_idAC3
Number of Residues4
Detailsbinding site for residue MG D 2003
ChainResidue
DASP739
DASP741
DASP743
QA4
site_idAC4
Number of Residues6
Detailsbinding site for residue ZN J 2001
ChainResidue
JCYS1112
JARG1189
JCYS1194
JTHR1196
JCYS1201
JCYS1204
site_idAC5
Number of Residues4
Detailsbinding site for residue ZN J 2002
ChainResidue
JCYS58
JCYS60
JCYS73
JCYS76
site_idAC6
Number of Residues4
Detailsbinding site for residue MG J 2003
ChainResidue
JASP739
JASP741
JASP743
TA4
Functional Information from PROSITE/UniProt
site_idPS00716
Number of Residues27
DetailsSIGMA70_2 Sigma-70 factors family signature 2. TleEVGayfgVTrerIrQIEnkaLrkL
ChainResidueDetails
FTHR397-LEU423
site_idPS00867
Number of Residues8
DetailsCPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. LIEANLRL
ChainResidueDetails
FLEU202-LEU209
site_idPS01166
Number of Residues13
DetailsRNA_POL_BETA RNA polymerases beta chain signature. GdKLANrHGNKGV
ChainResidueDetails
CGLY836-VAL848
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues22
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01322","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues38
DetailsDNA binding: {"description":"H-T-H motif","evidences":[{"source":"HAMAP-Rule","id":"MF_00963","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues140
DetailsRegion: {"description":"Sigma-70 factor domain-2"}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues156
DetailsRegion: {"description":"Sigma-70 factor domain-3"}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues104
DetailsRegion: {"description":"Sigma-70 factor domain-4"}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues6
DetailsMotif: {"description":"Interaction with polymerase core subunit RpoC"}
ChainResidueDetails

239803

PDB entries from 2025-08-06

PDB statisticsPDBj update infoContact PDBjnumon