6AOW

Crystal structure of lectin domain of F9 pilus adhesin FmlH from E. coli UTI89

Summary for 6AOW

Entry DOI	10.2210/pdb6aow/pdb
Descriptor	F9 pilus adhesin FmlH, SULFATE ION (3 entities in total)
Functional Keywords	fimbrial adhesin, lectin, bacterial adhesion, sugar binding protein
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	36128.36
Authors	Kalas, V.,Hultgren, S.J. (deposition date: 2017-08-16, release date: 2018-02-28, Last modification date: 2023-10-04)
Primary citation	Kalas, V.,Hibbing, M.E.,Maddirala, A.R.,Chugani, R.,Pinkner, J.S.,Mydock-McGrane, L.K.,Conover, M.S.,Janetka, J.W.,Hultgren, S.J. Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection. Proc.Natl.Acad.Sci.USA, 115:E2819-E2828, 2018 Cited by PubMed: 29507247 DOI: 10.1073/pnas.1720140115 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation