5YA8
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![BU of 5ya8 by Molmil](/molmil-images/mine/5ya8) | Crystal structure of scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity complexed with myo-inositol | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity | Authors: | Fukano, K, Shimizu, T, Sasaki, Y, Nakamura, A, Yajima, S. | Deposit date: | 2017-08-31 | Release date: | 2018-05-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of L-glucose oxidation by scyllo-inositol dehydrogenase: Implications for a novel enzyme subfamily classification PLoS ONE, 13, 2018
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5YKD
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6C7N
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![BU of 6c7n by Molmil](/molmil-images/mine/6c7n) | Monoclinic form of malic enzyme from sorghum at 2 angstroms resolution | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Malic enzyme, ... | Authors: | Trajtenberg, F, Alvarez, C, Buschiazzo, A. | Deposit date: | 2018-01-23 | Release date: | 2019-01-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular adaptations of NADP-malic enzyme for its function in C4photosynthesis in grasses. Nat.Plants, 5, 2019
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1TZ8
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![BU of 1tz8 by Molmil](/molmil-images/mine/1tz8) | The monoclinic crystal structure of transthyretin in complex with diethylstilbestrol | Descriptor: | ACETATE ION, CARBONATE ION, DIETHYLSTILBESTROL, ... | Authors: | Morais-de-Sa, E.M, Pereira, P.J.B, Saraiva, M.J, Damas, A.M. | Deposit date: | 2004-07-09 | Release date: | 2004-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors J.Biol.Chem., 279, 2004
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4WNC
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![BU of 4wnc by Molmil](/molmil-images/mine/4wnc) | Crystal structure of human wild-type GAPDH at 1.99 angstroms resolution | Descriptor: | ACETATE ION, Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Garcin, E.D. | Deposit date: | 2014-10-11 | Release date: | 2014-12-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | A Dimer Interface Mutation in Glyceraldehyde-3-Phosphate Dehydrogenase Regulates Its Binding to AU-rich RNA. J.Biol.Chem., 290, 2015
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4WNI
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1Q19
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![BU of 1q19 by Molmil](/molmil-images/mine/1q19) | Carbapenam Synthetase | Descriptor: | (2S,5S)-5-CARBOXYMETHYLPROLINE, CarA, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... | Authors: | Miller, M.T, Gerratana, B, Stapon, A, Townsend, C.A, Rosenzweig, A.C. | Deposit date: | 2003-07-18 | Release date: | 2003-11-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of Carbapenam Synthetase (CarA) J.Biol.Chem., 278, 2003
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8T65
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![BU of 8t65 by Molmil](/molmil-images/mine/8t65) | cA4 bound Cam1 | Descriptor: | Cam1, RNA (5'-R(P*AP*AP*AP*A)-3') | Authors: | Yu, Y, Patel, D.J. | Deposit date: | 2023-06-15 | Release date: | 2024-01-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | The CRISPR effector Cam1 mediates membrane depolarization for phage defence. Nature, 625, 2024
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7JPU
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5M66
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7RHZ
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8H75
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![BU of 8h75 by Molmil](/molmil-images/mine/8h75) | FGFR2 in complex with YJ001 | Descriptor: | CHLORIDE ION, Fibroblast growth factor receptor 2, Tinengotinib | Authors: | Yan, X.E, Yun, C.H. | Deposit date: | 2022-10-19 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.75 Å) | Cite: | FGFR2 in complex with YJ001 To Be Published
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7CE3
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![BU of 7ce3 by Molmil](/molmil-images/mine/7ce3) | Crystal structure of human IDH3 holoenzyme in APO form. | Descriptor: | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit beta, ... | Authors: | Sun, P.K, Ding, J.P. | Deposit date: | 2020-06-21 | Release date: | 2021-01-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.472 Å) | Cite: | Structure and allosteric regulation of human NAD-dependent isocitrate dehydrogenase. Cell Discov, 6, 2020
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6BNJ
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![BU of 6bnj by Molmil](/molmil-images/mine/6bnj) | Human hypoxanthine guanine phosphoribosyltransferase in complex with [3R,4R]-4-guanin-9-yl-3-((R)-2-hydroxy-2-phosphonoethyl)oxy-1-N-(phosphonopropionyl)pyrrolidine | Descriptor: | (3-{(3R,4R)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-[(2R)-2-hydroxy-2-phosphonoethoxy]pyrrolidin-1-yl}-3-oxopropy l)phosphonic acid, Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION | Authors: | Keough, D.T, Rejman, D, Guddat, L.W. | Deposit date: | 2017-11-16 | Release date: | 2017-12-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.909 Å) | Cite: | Design of Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitors as Potential Antimalarial Therapeutics. ACS Chem. Biol., 13, 2018
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1UJ2
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![BU of 1uj2 by Molmil](/molmil-images/mine/1uj2) | Crystal structure of human uridine-cytidine kinase 2 complexed with products, CMP and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... | Authors: | Suzuki, N.N, Koizumi, K, Fukushima, M, Matsuda, A, Inagaki, F. | Deposit date: | 2003-07-25 | Release date: | 2004-05-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase STRUCTURE, 12, 2004
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5D4Z
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1CH4
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![BU of 1ch4 by Molmil](/molmil-images/mine/1ch4) | MODULE-SUBSTITUTED CHIMERA HEMOGLOBIN BETA-ALPHA (F133V) | Descriptor: | CARBON MONOXIDE, MODULE-SUBSTITUTED CHIMERA HEMOGLOBIN BETA-ALPHA, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Shirai, T, Fujikake, M, Yamane, T, Inaba, K, Ishimori, K, Morishima, I. | Deposit date: | 1998-06-11 | Release date: | 1999-04-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of a protein with an artificial exon-shuffling, module M4-substituted chimera hemoglobin beta alpha, at 2.5 A resolution. J.Mol.Biol., 287, 1999
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5IS0
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![BU of 5is0 by Molmil](/molmil-images/mine/5is0) | Structure of TRPV1 in complex with capsazepine, determined in lipid nanodisc | Descriptor: | Transient receptor potential cation channel subfamily V member 1, capsazepine | Authors: | Gao, Y, Cao, E, Julius, D, Cheng, Y. | Deposit date: | 2016-03-15 | Release date: | 2016-05-25 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action. Nature, 534, 2016
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4WNL
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![BU of 4wnl by Molmil](/molmil-images/mine/4wnl) | The X-ray structure of a RNA-binding protein complex | Descriptor: | GLYCEROL, ISOPROPYL ALCOHOL, SULFATE ION, ... | Authors: | Singh, N, Blobel, G, Shi, H. | Deposit date: | 2014-10-13 | Release date: | 2014-12-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Hooking She3p onto She2p for myosin-mediated cytoplasmic mRNA transport. Proc.Natl.Acad.Sci.USA, 112, 2015
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5JA5
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![BU of 5ja5 by Molmil](/molmil-images/mine/5ja5) | Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) L111A and L130A mutant in complex with rice D53 repressor EAR peptide motif | Descriptor: | Protein TPR1, The rice D53 peptide (a.a. 794-808), ZINC ION | Authors: | Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K. | Deposit date: | 2016-04-12 | Release date: | 2017-07-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex. Sci Adv, 3, 2017
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8QVC
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![BU of 8qvc by Molmil](/molmil-images/mine/8qvc) | Deinococcus aerius TR0125 C-glucosyl deglycosidase (CGD), wild type crystal cryoprotected with glycerol | Descriptor: | CADMIUM ION, DUF6379 domain-containing protein, Xylose isomerase-like TIM barrel domain-containing protein | Authors: | Furlanetto, V, Kalyani, D.C, Kostelac, A, Haltrich, D, Hallberg, B.M, Divne, C. | Deposit date: | 2023-10-17 | Release date: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and Functional Characterization of a Gene Cluster Responsible for Deglycosylation of C-glucosyl Flavonoids and Xanthonoids by Deinococcus aerius. J.Mol.Biol., 436, 2024
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8BW9
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6DA6
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![BU of 6da6 by Molmil](/molmil-images/mine/6da6) | Crystal structure of the TtnD decarboxylase from the tautomycetin biosynthesis pathway of Streptomyces griseochromogenes, apo form at 2.6 A resolution (P212121) | Descriptor: | GLYCEROL, MAGNESIUM ION, UNKNOWN LIGAND, ... | Authors: | Han, L, Rudolf, J.D, Chang, C.-Y, Miller, M.D, Soman, J, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2018-05-01 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic Pathway. ACS Chem. Biol., 13, 2018
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5E4A
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![BU of 5e4a by Molmil](/molmil-images/mine/5e4a) | Human transthyretin (TTR) complexed with (2,7-Dichloro-fluoren-9-ylideneaminooxy)-acetic acid. | Descriptor: | Transthyretin, {[(2,7-dichloro-9H-fluoren-9-ylidene)amino]oxy}acetic acid | Authors: | Ciccone, L, Nencetti, S, Rossello, A, Orlandini, E, Stura, E.A. | Deposit date: | 2015-10-05 | Release date: | 2016-03-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR). J Enzyme Inhib Med Chem, 31, 2016
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4B91
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![BU of 4b91 by Molmil](/molmil-images/mine/4b91) | Crystal structure of truncated human CRMP-5 | Descriptor: | DIHYDROPYRIMIDINASE-RELATED PROTEIN 5 | Authors: | Ponnusamy, R, Lohkamp, B. | Deposit date: | 2012-08-31 | Release date: | 2013-02-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Insights Into the Oligomerization of Crmps: Crystal Structure of Human Collapsin Response Mediator Protein 5. J.Neurochem., 125, 2013
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