4UHY
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![BU of 4uhy by Molmil](/molmil-images/mine/4uhy) | Crystal structure of the human RGMA-BMP2 complex | Descriptor: | BONE MORPHOGENETIC PROTEIN 2, REPULSIVE GUIDANCE MOLECULE A | Authors: | Healey, E.G, Bishop, B, Elegheert, J, Bell, C.H, Padilla-Parra, S, Siebold, C. | Deposit date: | 2015-03-27 | Release date: | 2015-05-06 | Last modified: | 2015-06-17 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Repulsive Guidance Molecule is a Structural Bridge between Neogenin and Bone Morphogenetic Protein. Nat.Struct.Mol.Biol., 22, 2015
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7Z36
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![BU of 7z36 by Molmil](/molmil-images/mine/7z36) | Crystal structure of the KAP1 tripartite motif in complex with the ZNF93 KRAB domain | Descriptor: | Endolysin,Transcription intermediary factor 1-beta,Isoform 2 of Transcription intermediary factor 1-beta, SMARCAD1 CUE1 domain, ZINC ION, ... | Authors: | Stoll, G.A, Modis, Y. | Deposit date: | 2022-03-01 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure and functional mapping of the KRAB-KAP1 repressor complex. Embo J., 41, 2022
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8SLR
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![BU of 8slr by Molmil](/molmil-images/mine/8slr) | Crystal Structure of mouse TRAIL | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Pedersen, L.C, Xu, D. | Deposit date: | 2023-04-24 | Release date: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Heparan sulfate promotes TRAIL-induced tumor cell apoptosis. Elife, 12, 2024
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2IFO
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![BU of 2ifo by Molmil](/molmil-images/mine/2ifo) | |
7N6E
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![BU of 7n6e by Molmil](/molmil-images/mine/7n6e) | TCR peptide HLA-A2 complex | Descriptor: | Beta-2-microglobulin, MHC class I antigen, Spike protein S1, ... | Authors: | Chaurasia, P, Rossjohn, J, Petersen, J. | Deposit date: | 2021-06-08 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein. J.Biol.Chem., 297, 2021
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7N6D
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![BU of 7n6d by Molmil](/molmil-images/mine/7n6d) | HLA peptide complex | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, MHC class I antigen, ... | Authors: | Chaurasia, P, Petersen, J, Rossjohn, J. | Deposit date: | 2021-06-08 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein. J.Biol.Chem., 297, 2021
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7A00
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![BU of 7a00 by Molmil](/molmil-images/mine/7a00) | Crystal structure of Shank1 PDZ in complex with L6F mutant of the C-terminal hexapeptide from GKAP | Descriptor: | L6F mutant of C-terminal hexapeptide from Guanylate kinase-associated protein, SH3 and multiple ankyrin repeat domains protein 1 | Authors: | Zsofia, H, Hetherington, K, Fruzsina, H, Edwards, T.A, Wilson, A.J. | Deposit date: | 2020-08-05 | Release date: | 2021-07-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Query-guided protein-protein interaction inhibitor discovery. Chem Sci, 12, 2021
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8SJ2
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8SJ8
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![BU of 8sj8 by Molmil](/molmil-images/mine/8sj8) | Structure of binary complex of human cGAS and bound ppp(2'-5')GpG | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION, [[(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | Authors: | Wu, S, Sohn, J. | Deposit date: | 2023-04-17 | Release date: | 2024-04-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
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8SJ0
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8SI0
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![BU of 8si0 by Molmil](/molmil-images/mine/8si0) | |
6U50
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![BU of 6u50 by Molmil](/molmil-images/mine/6u50) | Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB) | Authors: | Taylor, A.B, Sherwood, L.J, Hart, P.J, Hayhurst, A. | Deposit date: | 2019-08-26 | Release date: | 2019-11-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Paratope Duality and Gullying are Among the Atypical Recognition Mechanisms Used by a Trio of Nanobodies to Differentiate Ebolavirus Nucleoproteins. J.Mol.Biol., 431, 2019
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6U53
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8SHY
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![BU of 8shy by Molmil](/molmil-images/mine/8shy) | |
8SHK
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4UQ3
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![BU of 4uq3 by Molmil](/molmil-images/mine/4uq3) | Crystal structure of HLA-A0201 in complex with an azobenzene- containing peptide | Descriptor: | AZOBENZENE-CONTAINING PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | Authors: | Thong, S.Y, Yap, J.W, Lim, P.Y, Verhelst, S.H, Lescar, J, Meijers, R, Grotenbreg, G.M. | Deposit date: | 2014-06-19 | Release date: | 2014-09-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptides. Angew. Chem. Int. Ed. Engl., 53, 2014
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8SJ1
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6U7A
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![BU of 6u7a by Molmil](/molmil-images/mine/6u7a) | Rv3722c in complex with kynurenine | Descriptor: | (2S)-4-(2-aminophenyl)-2-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-4-oxobutanoic acid, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-hydroxyquinoline-2-carboxylic acid, ... | Authors: | Mandyoli, L, Sacchettini, J. | Deposit date: | 2019-09-01 | Release date: | 2020-05-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis. Nat Commun, 11, 2020
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4UQ2
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![BU of 4uq2 by Molmil](/molmil-images/mine/4uq2) | Crystal structure of HLA-A1101 in complex with an azobenzene- containing peptide | Descriptor: | AZOBENZENE-CONTAINING PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | Authors: | Thong, S.Y, Yap, J.W, Lim, P.Y, Verhelst, S.H, Lescar, J, Meijers, R, Grotenbreg, G.M. | Deposit date: | 2014-06-19 | Release date: | 2014-09-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Bioorthogonal Cleavage and Exchange of Major Histocompatibility Complex Ligands by Employing Azobenzene-Containing Peptides. Angew.Chem.Int.Ed.Engl., 53, 2014
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4UC6
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![BU of 4uc6 by Molmil](/molmil-images/mine/4uc6) | N-terminal globular domain of the RSV Nucleoprotein | Descriptor: | NUCLEOPROTEIN, SULFATE ION | Authors: | Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S. | Deposit date: | 2014-12-03 | Release date: | 2015-08-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus. J.Virol., 89, 2015
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4UC8
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![BU of 4uc8 by Molmil](/molmil-images/mine/4uc8) | N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal phenylalanine of the Phosphoprotein | Descriptor: | GLYCEROL, NUCLEOPROTEIN, PHENYLALANINE, ... | Authors: | Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S. | Deposit date: | 2014-12-03 | Release date: | 2015-08-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus. J.Virol., 89, 2015
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8S0N
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4UKD
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![BU of 4ukd by Molmil](/molmil-images/mine/4ukd) | UMP/CMP KINASE FROM SLIME MOLD COMPLEXED WITH ADP, UDP, BERYLLIUM FLUORIDE | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM DIFLUORIDE, MAGNESIUM ION, ... | Authors: | Schlichting, I, Reinstein, J. | Deposit date: | 1997-05-20 | Release date: | 1998-05-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of active conformations of UMP kinase from Dictyostelium discoideum suggest phosphoryl transfer is associative. Biochemistry, 36, 1997
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6U9A
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![BU of 6u9a by Molmil](/molmil-images/mine/6u9a) | Hsp90a NTD K58R bound reversibly to sulfonyl fluoride 5 | Descriptor: | 3-{[(3S)-3-({6-amino-8-[(6-iodo-2H-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-9-yl}methyl)piperidin-1-yl]methyl}benzene-1-sulfonyl fluoride, Heat shock protein HSP 90-alpha | Authors: | Cuesta, A, Wan, X, Taunton, J. | Deposit date: | 2019-09-07 | Release date: | 2020-02-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Ligand Conformational Bias Drives Enantioselective Modification of a Surface-Exposed Lysine on Hsp90. J.Am.Chem.Soc., 142, 2020
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8EL5
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![BU of 8el5 by Molmil](/molmil-images/mine/8el5) | Light harvesting phycobiliprotein HaPE555 from the cryptophyte Hemiselmis andersenii CCMP644 in an alternating tight to loose interface filament | Descriptor: | DiCys-(15,16)-Dihydrobiliverdin, GLYCEROL, PHYCOERYTHROBILIN, ... | Authors: | Rathbone, H.W, Michie, K.A, Laos, A.L, Curmi, P.M.G. | Deposit date: | 2022-09-23 | Release date: | 2023-10-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Molecular dissection of the soluble photosynthetic antenna from the cryptophyte alga Hemiselmis andersenii. Commun Biol, 6, 2023
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