7A00
Crystal structure of Shank1 PDZ in complex with L6F mutant of the C-terminal hexapeptide from GKAP
Summary for 7A00
Entry DOI | 10.2210/pdb7a00/pdb |
Descriptor | SH3 and multiple ankyrin repeat domains protein 1, L6F mutant of C-terminal hexapeptide from Guanylate kinase-associated protein (3 entities in total) |
Functional Keywords | shank1 pdz, gkap, peptide binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 26238.26 |
Authors | Zsofia, H.,Hetherington, K.,Fruzsina, H.,Edwards, T.A.,Wilson, A.J. (deposition date: 2020-08-05, release date: 2021-07-07, Last modification date: 2024-01-31) |
Primary citation | Celis, S.,Hobor, F.,James, T.,Bartlett, G.J.,Ibarra, A.A.,Shoemark, D.K.,Hegedus, Z.,Hetherington, K.,Woolfson, D.N.,Sessions, R.B.,Edwards, T.A.,Andrews, D.M.,Nelson, A.,Wilson, A.J. Query-guided protein-protein interaction inhibitor discovery. Chem Sci, 12:4753-4762, 2021 Cited by PubMed: 34163731DOI: 10.1039/d1sc00023c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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